Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathryn J, Quigley"'
Autor:
Lies Boelen, Patrick K O'Neill, Kathryn J Quigley, Catherine J Reynolds, Bernard Maillere, John H Robinson, Ganjana Lertmemongkolchai, Daniel M Altmann, Rosemary J Boyton, Becca Asquith
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 3, p e1004796 (2016)
Activation of CD4+ T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual's HLA class II genotype, identifying which clas
Externí odkaz:
https://doaj.org/article/bf41c06d42fd4022a66f3f8a1f57a94c
Autor:
Malcolm J. W. Sim, Janet Stowell, Jiten Manji, Catherine J. Reynolds, Rosemary J. Boyton, Xiaoming Cheng, Kathryn J. Quigley, Katherine Choy, Sundas Tahir, Tracey Pollard, Sara A. Mathie, Simone A. Walker, Fiyyaz Ahmed-Jushuf, Daniel M. Altmann, Apurva Suresh, Khizr Nawab
IL-8-dependent inflammation is a hallmark of host lung innate immunity to bacterial pathogens, yet in many human lung diseases, including chronic obstructive pulmonary disease, bronchiectasis, and pulmonary fibrosis, there are progressive, irreversib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74400730cd459279dce3b6d255e40b9
http://hdl.handle.net/10044/1/60795
http://hdl.handle.net/10044/1/60795
Autor:
Daniel M. Altmann, Diana Bilton, Michael R. Loebinger, Rosemary J. Boyton, Kathryn J. Quigley, Bernard Maillere, Catherine J. Reynolds, Amelie Goudet, Robert Wilson, Eleanor J. Raynsford, Ruhena Sergeant, Stefan Worgall, A. Quigley
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 191:1250-1264
Rationale: Pseudomonas aeruginosa (PA) is an environmental pathogen that commonly infects individuals with cystic fibrosis (CF) and non-CF bronchiectasis, impacting morbidity and mortality. To understand the pathobiology of interactions between the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05627c42a08308dd1ce3fb300581ed9e
https://doi.org/10.1164/rccm.201411-1995oc
https://doi.org/10.1164/rccm.201411-1995oc
Autor:
Patricia Lassaux, Manutsanun Sumonwiriya, Louise J. Gourlay, Kemajittra Jenjaroen, Daniel M. Altmann, Direk Limmathurotsakul, Susanna Dunachie, Catherine J. Reynolds, Pitchayanant Ariyaprasert, Nicholas P. J. Day, Charuporn Promwong, Ruhena Sergeant, Panjaporn Chaichana, Prapit Teparrukkul, Rosemary J. Boyton, Kathryn J. Quigley, Suchintana Chumseng
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Melioidosis, caused by Burkholderia pseudomallei, is a potentially lethal infection with no licensed vaccine. There is little understanding of why some exposed individuals have no symptoms, while others rapidly progress to sepsis and death, or why di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581907d66612757c0b84f54c2a052e07
http://hdl.handle.net/10044/1/53421
http://hdl.handle.net/10044/1/53421
Autor:
Stephen J. Till, Rosemary J. Boyton, Agnieszka Grzybowska-Kowalczyk, Catherine J. Reynolds, Bernard Maillere, William W. Kwok, Eleanor J. Raynsford, Stephen R. Durham, Andrea Goldstone, Kathryn J. Quigley, Lavina R Saggar, Daniel M. Altmann
Publikováno v:
Thorax. 69:335-345
Background T-cell targeted peptide epitope tolerogens from grass pollen allergens may be useful in treating seasonal allergic rhinitis, but there is urgent need for optimisation of approaches from improved understanding of mechanism. Objective We sou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e593abce4ea96653b44ccc533983400
https://doi.org/10.1136/thoraxjnl-2013-204324
https://doi.org/10.1136/thoraxjnl-2013-204324
Publikováno v:
Clinical and Experimental Immunology. 171:117-123
Summary Recent studies analysing immunogenetics and immune mechanisms controlling susceptibility to chronic bacterial infection in bronchiectasis implicate dysregulated immunity in conjunction with chronic bacterial infection. Bronchiectasis is a str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0448db614d6fd294dcd55474585d8ed1
https://doi.org/10.1111/cei.12003
https://doi.org/10.1111/cei.12003
Autor:
Michael Poidinger, Kathryn J. Quigley, Rosemary J. Boyton, Catherine B. Reynolds, Daniel M. Altmann
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
BACKGROUND: Interleukin-8 ( IL-8)-dependent neutrophilia is a feature of innate immunity to lung microbial pathogens, yet many lung diseases themselves encompass pathologic consequences of chronic, excessive, IL-8 release. These diseases include cyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ce9544361c1e932e2adebbaa4490a0
https://doi.org/10.1183/13993003.congress-2016.pa3972
https://doi.org/10.1183/13993003.congress-2016.pa3972
Autor:
Catherine B. Reynolds, Rosemary J. Boyton, Francesco Dazzi, Kathryn J. Quigley, Janet Stowell, Daniel M. Altmann
Publikováno v:
10.1 Respiratory Infections.
BACKGROUND: Mesenchymal stem cells (MSCs) regulate lung inflammation, and enhance bacterial clearance and survival in preclinical models of pneumonia and sepsis 1-3 ,making them a possible treatment for bacterial lung infection resistant to antibioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b637ff449bbbab34c1905b981c237ae
https://doi.org/10.1183/13993003.congress-2016.pa2624
https://doi.org/10.1183/13993003.congress-2016.pa2624
Autor:
Lies, Boelen, Patrick K, O'Neill, Kathryn J, Quigley, Catherine J, Reynolds, Bernard, Maillere, John H, Robinson, Ganjana, Lertmemongkolchai, Daniel M, Altmann, Rosemary J, Boyton, Becca, Asquith
Publikováno v:
PLoS Computational Biology
Activation of CD4+ T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual’s HLA class II genotype, identifying which cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a977f170adc00f1306b1ed892a611110
https://pubmed.ncbi.nlm.nih.gov/26953935
https://pubmed.ncbi.nlm.nih.gov/26953935
Autor:
Rosemary J. Boyton, Daniel M. Altmann, Kathryn J. Quigley, Malcolm J. W. Sim, Catherine J. Reynolds
Publikováno v:
Journal of Neuroinflammation
Background Multiple sclerosis is generally considered an autoimmune disease resulting from interaction between predisposing genes and environmental factors, together allowing immunological self-tolerance to be compromised. The precise nature of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0c93b1d4e791db9e247e4d5ec2d6fc
https://doi.org/10.1186/s12974-015-0313-9
https://doi.org/10.1186/s12974-015-0313-9