Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathryn H, Milne"'
Autor:
Susanne Helena Hodgson, David Llewellyn, Sarah Silk, Kathryn H Milne, Sean C Elias, Kazutoyo Miura, Gathoni Kamuyu, Elizabeth Juma, Charles Magiri, Alfred Musau Muia, Jing Jin, Alexandra J Spencer, Rhea Jessica Longley, Thomas Mercier, Laurent Decosterd, Carole A Long, Faith HA Osier, Stephen Hoffman, Bernhards Ragama Ogutu, Adrian V.S. Hill, Kevin Marsh, Simon J Draper
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Background: The timing of infection is closely determined in controlled human malaria infection (CHMI) studies, and as such they provide a unique opportunity to dissect changes in immunological responses before and after a single infection. The first
Externí odkaz:
https://doaj.org/article/550880d79dd64b4f9ce906d28573e21b
Autor:
Kathryn H. Milne, J. A. Rowe, M. Regato, Washington B. Cárdenas, João R. C. Andrade, Simon Rogers, Philip J Spence, Laura Botana, A.-M. Nastase, F. Bertuccez Cordeiro, J. Chang, Eugenia Carrillo, Javier Moreno, M. Zambrano, Michael P. Barrett
Acute febrile illnesses are still a major cause of mortality and morbidity globally, particularly in low to middle income countries. The aim of this study was to determine any possible metabolic commonalities of patients infected with disparate patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a0aea093f3edf64cf5c5a39fd1c815b
https://doi.org/10.1101/2021.09.02.458540
https://doi.org/10.1101/2021.09.02.458540
Autor:
Sumi Biswas, Prateek Choudhary, Sean C Elias, Kazutoyo Miura, Kathryn H Milne, Simone C de Cassan, Katharine A Collins, Fenella D Halstead, Carly M Bliss, Katie J Ewer, Faith H Osier, Susanne H Hodgson, Christopher J A Duncan, Geraldine A O'Hara, Carole A Long, Adrian V S Hill, Simon J Draper
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107903 (2014)
The development of protective vaccines against many difficult infectious pathogens will necessitate the induction of effective antibody responses. Here we assess humoral immune responses against two antigens from the blood-stage merozoite of the Plas
Externí odkaz:
https://doaj.org/article/4340a1d9465243e3a0e7d6be40297708
Autor:
Matthew Berriman, J. Alexandra Rowe, Simon J. Draper, Michael P. Barrett, Sarah E. Silk, Geetha Sankaranarayanan, Wiebke Nahrendorf, Philip J Spence, Diana Munoz Sandoval, Mandy Sanders, Angela M. Minassian, Clément Regnault, Alasdair Ivens, Ruth O. Payne, N Venkatraman, Adam J. Reid, Magda E. Lotkowska, Áine O'Toole, Kathryn H. Milne, Nick J. Edwards, Adrian V. S. Hill
Publikováno v:
eLife, Vol 10 (2021)
Milne, K, Ivens, A, Reid, A J, Lotkowska, M E, O'Toole, Á, Sankaranarayanan, G, Munoz Sandoval, D, Nahrendorf, W, Regnault, C, Edwards, N J, Silk, S E, Payne, R O, Minassian, A M, Venkatraman, N, Sanders, M, Hill, A V S, Barrett, M P, Berriman, M, Draper, S J, Rowe, A J & Spence, P J 2021, ' Mapping immune variation and var gene switching in naïve hosts infected with Plasmodium falciparum ', eLIFE, vol. 10, e62800 . https://doi.org/10.7554/eLife.62800
Milne, K, Ivens, A, Reid, A J, Lotkowska, M E, O'Toole, Á, Sankaranarayanan, G, Munoz Sandoval, D, Nahrendorf, W, Regnault, C, Edwards, N J, Silk, S E, Payne, R O, Minassian, A M, Venkatraman, N, Sanders, M, Hill, A V S, Barrett, M P, Berriman, M, Draper, S J, Rowe, A J & Spence, P J 2021, ' Mapping immune variation and var gene switching in naïve hosts infected with Plasmodium falciparum ', eLIFE, vol. 10, e62800 . https://doi.org/10.7554/eLife.62800
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, ask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dabfbdeab670e7303331411e94d6707
https://elifesciences.org/articles/62800
https://elifesciences.org/articles/62800
Autor:
Adrian V. S. Hill, Simon J. Draper, Matthew Berriman, Ruth O. Payne, N Venkatraman, J. Alexandra Rowe, Clément Regnault, Michael P. Barrett, Nick J. Edwards, Philip J Spence, Geetha Sankaranarayanan, Sarah E. Silk, Mandy Sanders, Angela M. Minassian, Diana Munoz Sandoval, Kathryn H. Milne, Magda E. Lotkowska, Áine O'Toole, Alasdair Ivens, Wiebke Nahrendorf, Adam J. Reid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03827e696dd9dfb2b3297deaa5b825d3
https://doi.org/10.7554/elife.62800.sa2
https://doi.org/10.7554/elife.62800.sa2
Autor:
Kathryn H. Milne
Publikováno v:
The Historian. 83:83-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::211b1f71c0b396f818f2e9877085bade
https://doi.org/10.1080/00182370.2021.1933814
https://doi.org/10.1080/00182370.2021.1933814
Autor:
Kathryn A, Hjerrild, Jing, Jin, Katherine E, Wright, Rebecca E, Brown, Jennifer M, Marshall, Geneviève M, Labbé, Sarah E, Silk, Catherine J, Cherry, Stine B, Clemmensen, Thomas, Jørgensen, Joseph J, Illingworth, Daniel G W, Alanine, Kathryn H, Milne, Rebecca, Ashfield, Willem A, de Jongh, Alexander D, Douglas, Matthew K, Higgins, Simon J, Draper
Publikováno v:
Scientific Reports
The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) has recently emerged as a leading candidate antigen against the blood-stage human malaria parasite. However it has proved challenging to identify a heterologous expression platf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c27f6ca2bfb0bd328787829a667c71f
https://pubmed.ncbi.nlm.nih.gov/27457156
https://pubmed.ncbi.nlm.nih.gov/27457156
Autor:
Cécile Crosnier, Alexandra J. Spencer, Luis A. Lugo-Roman, Kimberly A. Edgel, Kathryn A. Hjerrild, Lynn Lambert, Alexander D. Douglas, Kathryn H. Milne, Julio A. Ventocilla, Carmen Lucas, Joseph J. Illingworth, Jeromy T. Moorhead, Yimin Wu, Andres G. Lescano, G. Christian Baldeviano, A Turner, Gavin J. Wright, Simon J. Draper, Daniel G. W. Alanine, Carole A. Long, Kazutoyo Miura, Karina P. Leiva, S. Josefin Bartholdson, Ababacar Diouf
Publikováno v:
Cell Host & Microbe
Summary Antigenic diversity has posed a critical barrier to vaccine development against the pathogenic blood-stage infection of the human malaria parasite Plasmodium falciparum. To date, only strain-specific protection has been reported by trials of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34e984e3483c22007a31bb00b630247
http://ora.ox.ac.uk/objects/uuid:32f2ffc6-887f-40ac-a07d-2b08a4de7de4
http://ora.ox.ac.uk/objects/uuid:32f2ffc6-887f-40ac-a07d-2b08a4de7de4
Autor:
Kathryn H. Milne, Sean C. Elias, Susanne H. Hodgson, Simon J. Draper, Cecilia Chui, Persephone Borrow
Publikováno v:
Malaria Journal
Background Here we report on a Phase Ia clinical vaccine trial using the AMA1 antigen from the blood-stage Plasmodium falciparum malaria parasite. A variety of promising ‘mixed-modality’ regimens were tested, with all volunteers primed with chimp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81372e6d7f6efefcfa41d543b4fb276b
https://doi.org/10.1186/1475-2875-13-s1-p28
https://doi.org/10.1186/1475-2875-13-s1-p28