Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kathryn G. Scheld"'
Autor:
S.Edward Lee, Graham Rickett, Dennis E. Danley, Mark Ammirati, Kathryn G. Scheld, Peter M. Hobart, James R. Merson, Kieran F. Geoghegan, Steven J. Hawrylik
Publikováno v:
Biochemical and Biophysical Research Communications. 165:1043-1050
A plasmid vector was used to express the HIV-1 pol open reading frame under the regulation of the bacterial trp promoter in Escherichia coli. This expression system has been used as a source of recombinant viral protease. The self-processed active en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cb6e13bf0dbafd5b462b83fa0572c3
https://doi.org/10.1016/0006-291x(89)92707-1
https://doi.org/10.1016/0006-291x(89)92707-1
Autor:
Shih-Jen Edward Lee, Steven J. Hawrylik, Stephen A. Wood, John P. Overington, Kathryn G. Scheld, Andrew M. Hemmings, Andrew F. Wilderspin, Dennis E. Danley, Peter John Whittle, R. Lapatto, Tom L. Blundell, James Merson, Peter M. Hobart, Kieran F. Geoghegan
Publikováno v:
Nature. 342:299-302
Knowledge of the tertiary structure of the proteinase from human immunodeficiency virus HIV-1 is important to the design of inhibitors that might possess antiviral activity and thus be useful in the treatment of AIDS. The conserved Asp-Thr/Ser-Gly se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8b9bc36bc5b414a3a2ed397a8096b9
https://doi.org/10.1038/342299a0
https://doi.org/10.1038/342299a0