Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kathryn Furr"'
Autor:
Fahmida Rasha, Geetha Priya Boligala, Mingxiao V. Yang, Dalia Martinez-Marin, Isabel Castro-Piedras, Kathryn Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Maribel Castro, Hafiz Khan, Nusrat Jahan, Sharilyn Almodovar, Michael W. Melkus, Kevin Pruitt, Rakhshanda Layeequr Rahman
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Dishevelled paralogs (DVL1, 2, 3) are key mediators of Wnt pathway playing a role in constitutive oncogenic signaling influencing the tumor microenvironment. While previous studies showed correlation of β-catenin with T cell gene
Externí odkaz:
https://doaj.org/article/8ea1b3462046437d99d48335c2b3d3bc
Autor:
Leila Eslamizar, Constantinos Petrovas, David J. Leggat, Kathryn Furr, Michelle L. Lifton, Gail Levine, Steven Ma, Christopher Fletez-Brant, Wesley Hoyland, Madhu Prabhakaran, Sandeep Narpala, Kristin Boswell, Takuya Yamamoto, Hua-Xin Liao, David Pickup, Elizabeth Ramsburg, Laura Sutherland, Adrian McDermott, Mario Roederer, David Montefiori, Richard A. Koup, Barton F. Haynes, Norman L. Letvin, Sampa Santra
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract The RV144 HIV-1 vaccine trial has been the only clinical trial to date that has shown any degree of efficacy and associated with the presence of vaccine-elicited HIV-1 envelope-specific binding antibody and CD4+ T-cell responses. This trial
Externí odkaz:
https://doaj.org/article/63b38173c836479fba679161167f0413
Autor:
Robert Parks, Kelly E. Seaton, Barton F. Haynes, Jim Tartaglia, Jeffrey Tomalka, Muhammad Bilal Latif, Georgia D. Tomaras, Slim Fourati, Ana María González, Adam Pelletier, Nelson L. Michael, Richard A. Koup, Rafick Pierre Sekaly, Peter Wilkinson, Genoveffa Franchini, Merlin L. Robb, Norman L. Letvin, Kathryn Furr, Sampa Santra, Michelle A. Lifton, Nicole L. Yates, Ashish Sharma, Kevin R. Carlson
Publikováno v:
Nature Immunology. 22:1294-1305
Development of effective human immunodeficiency virus 1 (HIV-1) vaccines requires synergy between innate and adaptive immune cells. Here we show that induction of the transcription factor CREB1 and its target genes by the recombinant canarypox vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5894e65d5dda882b45064379bbab429a
https://doi.org/10.1038/s41590-021-01026-9
https://doi.org/10.1038/s41590-021-01026-9
Autor:
Laura L. Sutherland, Takuya Yamamoto, Barton F. Haynes, Norman L. Letvin, Madhu Prabhakaran, Wesley Hoyland, Sandeep Narpala, David J. Pickup, Steven Ma, Christopher Fletez-Brant, Mario Roederer, Sampa Santra, Adrian B. McDermott, Hua-Xin Liao, Richard A. Koup, Michelle L. Lifton, Elizabeth Ramsburg, Kristin L. Boswell, Gail Levine, Constantinos Petrovas, Leila Eslamizar, David J. Leggat, Kathryn Furr, David C. Montefiori
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
The RV144 HIV-1 vaccine trial has been the only clinical trial to date that has shown any degree of efficacy and associated with the presence of vaccine-elicited HIV-1 envelope-specific binding antibody and CD4+ T-cell responses. This trial also show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b4872fd248bac882951b8abd1964cd
https://pubmed.ncbi.nlm.nih.gov/33495459
https://pubmed.ncbi.nlm.nih.gov/33495459
Autor:
Jeffrey Alan, Tomalka, Adam Nicolas, Pelletier, Slim, Fourati, Muhammad Bilal, Latif, Ashish, Sharma, Kathryn, Furr, Kevin, Carlson, Michelle, Lifton, Ana, Gonzalez, Peter, Wilkinson, Genoveffa, Franchini, Robert, Parks, Norman, Letvin, Nicole, Yates, Kelly, Seaton, Georgia, Tomaras, Jim, Tartaglia, Merlin L, Robb, Nelson L, Michael, Richard, Koup, Barton, Haynes, Sampa, Santra, Rafick Pierre, Sekaly
Publikováno v:
Nature immunology. 22(10)
Development of effective human immunodeficiency virus 1 (HIV-1) vaccines requires synergy between innate and adaptive immune cells. Here we show that induction of the transcription factor CREB1 and its target genes by the recombinant canarypox vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2a0ec623ab466767ebae7e903987710
https://pubmed.ncbi.nlm.nih.gov/34556875
https://pubmed.ncbi.nlm.nih.gov/34556875
Publikováno v:
The Journal of Immunology. 204:87.32-87.32
Acute graft vs. host disease (aGVHD) is a major complication following hematopoietic stem cell transplantation. Preclinical and clinical studies suggest aGVHD may be potentiated by gut damage and translocation of intestinal microbiota following toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df122d824d2b66b2923d7e367c0b9cf3
https://doi.org/10.4049/jimmunol.204.supp.87.32
https://doi.org/10.4049/jimmunol.204.supp.87.32
Publikováno v:
The Journal of Immunology. 204:87.31-87.31
Mice are the primary animal of choice for modeling aGVHD. One aspect of these mouse models that may limit translation of promising therapeutic strategies to patient treatment is the use inbred mice as surrogates for genetically diverse human populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81d83fcab43daa5875b45c292d813d9d
https://doi.org/10.4049/jimmunol.204.supp.87.31
https://doi.org/10.4049/jimmunol.204.supp.87.31
Publikováno v:
The Journal of Immunology. 202:69.3-69.3
Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially life-saving treatment for refractory/relapsing hematological malignancies, blood disorders or autoimmune diseases. However, approximately 40–50% of patients undergoing allog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f53c06f4ddd183e4d40ee54b90d7f8a
https://doi.org/10.4049/jimmunol.202.supp.69.3
https://doi.org/10.4049/jimmunol.202.supp.69.3
Publikováno v:
The Journal of Immunology. 202:69.22-69.22
A major limitation with use of hematopoietic stem cell transplantation to treat relapsing hematological malignancies is the development of a potentially lethal, multi-organ inflammatory disorder called acute graft versus host disease (aGVHD). Acute G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dd1d7cda8ce1ec57b65a52ca025f2f1
https://doi.org/10.4049/jimmunol.202.supp.69.22
https://doi.org/10.4049/jimmunol.202.supp.69.22
Publikováno v:
Mucosal Immunology. 6:93-103
An HIV-1 vaccine must elicit a clonally diverse virus-specific CD8+ T-cell response to contain mutant virus forms, and these responses must be present in mucosal tissues, which are the site of early HIV-1 replication. We show that systemic delivery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7105a722c2cc008f74905225f4552a
https://doi.org/10.1038/mi.2012.52
https://doi.org/10.1038/mi.2012.52