Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Kathryn E. Saatman"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Traumatic brain injury (TBI) increases gastrointestinal morbidity and associated mortality. Clinical and preclinical studies implicate gut dysbiosis as a consequence of TBI and an amplifier of brain damage. However, little is known about the
Externí odkaz:
https://doaj.org/article/961f185d97ab437cba8613e2aa448413
Publikováno v:
Viruses, Vol 16, Iss 1, p 55 (2023)
Platelets express several surface receptors that could interact with different viruses. To understand the mechanisms of HIV-1′s interaction with platelets, we chose the EcoHIV model. While EcoHIV is an established model for neuroAIDS, its effects o
Externí odkaz:
https://doaj.org/article/e6376bb734d84d9c9f9a052e6bc2edaa
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 4, Pp n/a-n/a (2022)
Abstract Background Traumatic brain injury (TBI) results in neurovascular damage that initiates intrinsic mechanisms of hypercoagulation, which can contribute to the development of life‐threatening complications, such as coagulopathy and delayed th
Externí odkaz:
https://doaj.org/article/d545223b28be42b1a85f87eb36479cd0
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Cellular damage associated with traumatic brain injury (TBI) manifests in motor and cognitive dysfunction following injury. Experimental models of TBI reveal cell death in the granule cell layer (GCL) of the hippocampal dentate gyrus acutely
Externí odkaz:
https://doaj.org/article/78bea642f5284131a65ad30664930da0
Autor:
Erica L. Littlejohn, Anthony J. DeSana, Hannah C. Williams, Rudy T. Chapman, Binoy Joseph, Jelena A. Juras, Kathryn E. Saatman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Adult hippocampal neurogenesis is stimulated acutely following traumatic brain injury (TBI). However, many hippocampal neurons born after injury develop abnormally and the number that survive long-term is debated. In experimental TBI, insulin-like gr
Externí odkaz:
https://doaj.org/article/d4769e469e284423939225bf4b53768b
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Insulin-like growth factor 1 (IGF-1) is known to have diverse effects on brain structure and function, including the promotion of stem cell proliferation and neurogenesis in the adult dentate gyrus. However, the intracellular pathways downst
Externí odkaz:
https://doaj.org/article/e2ae59a77df6443398e78c028a1d3e03
Autor:
William Brad Hubbard, Meenakshi Banerjee, Hemendra Vekaria, Kanakanagavalli Shravani Prakhya, Smita Joshi, Qing Jun Wang, Kathryn E. Saatman, Sidney W. Whiteheart, Patrick G. Sullivan
Publikováno v:
Cells, Vol 10, Iss 3, p 500 (2021)
Traumatic brain injury (TBI) affects over 3 million individuals every year in the U.S. There is growing appreciation that TBI can produce systemic modifications, which are in part propagated through blood–brain barrier (BBB) dysfunction and blood
Externí odkaz:
https://doaj.org/article/f85b8a1981654faab392df9890157331
Autor:
Marek Ma, Toby A. Ferguson, Kathleen M. Schoch, Jian Li, Yaping Qian, Frances S. Shofer, Kathryn E. Saatman, Robert W. Neumar
Publikováno v:
Neurobiology of Disease, Vol 56, Iss , Pp 34-46 (2013)
In both the central nervous system (CNS) and peripheral nervous system (PNS), transected axons undergo Wallerian degeneration. Even though Augustus Waller first described this process after transection of axons in 1850, the molecular mechanisms may b
Externí odkaz:
https://doaj.org/article/bf91bd1d413b4af4bfd31e4befe8b270
Autor:
Rhona McGonigal, Madeleine E. Cunningham, Duncan Smyth, Michael Chou, Jennifer A. Barrie, Andrew Wilkie, Clare Campbell, Kathryn E. Saatman, Michael Lunn, Hugh J. Willison
Publikováno v:
Journal of the Peripheral Nervous System. 28:4-16
Autor:
Mehrana Mohtasebi, Daniel Irwin, Dara Singh, Siavash Mazdeyasna, Xuhui Liu, Samaneh Rabienia Haratbar, Faraneh Fathi, Chong Huang, Kathryn E. Saatman, Lei Chen, Guoqiang Yu
Publikováno v:
Journal of Biomedical Optics. 28