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pro vyhledávání: '"Kathryn E. Sánchez"'
Autor:
Kathryn E. Sánchez, Shanya Jiang, Sharina Palencia Desai, Jeffery Thompson, Sasha Hobson, Gary A. Rosenberg, Kiran Bhaskar
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102916- (2024)
Summary: Apoptosis-associated speck-like protein containing a c-terminal caspase activation and recruitment domain (ASC) specks are elevated in the cerebrospinal fluid (CSF) of Alzheimer’s disease and related dementias (AD/ADRDs) patients. Here, we
Externí odkaz:
https://doaj.org/article/cdb71a31e5af421cb405829c89c0a119
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Inflammation contributes to amyloid-β and tau pathology in Alzheimer’s disease (AD). Microglia facilitate an altered immune response that includes microgliosis, upregulation of inflammasome proteins, and elevation of matrix-metalloproteinases (MMP
Externí odkaz:
https://doaj.org/article/46de3c30db5347a4b84c8cd043e8ba03
Autor:
Kathryn E. Sánchez, Gary A. Rosenberg
Publikováno v:
International journal of molecular sciences. 23(9)
Though COVID-19 is primarily characterized by symptoms in the periphery, it can also affect the central nervous system (CNS). This has been established by the association between stroke and COVID-19. However, the molecular mechanisms that cause strok