Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kathryn E. Nichol"'
Publikováno v:
Alzheimer's & Dementia. 5:287-294
Background Human studies on exercise, cognition, and apolipoprotein E ( APOE ) genotype show that e4 carriers may benefit from regular physical activity. Methods We examined voluntary wheel-running, memory, and hippocampal plasticity in APOE e3 and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e924d4d623c8dbc771cf8dd6fb9229f
https://doi.org/10.1016/j.jalz.2009.02.006
https://doi.org/10.1016/j.jalz.2009.02.006
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 1, Pp 121-129 (2008)
Exercise is a treatment paradigm that can ameliorate cognitive dysfunction in Alzheimer disease (AD) and AD mouse models. Since exercise is also known to alter the peripheral immune response, one potential mechanism for the cognitive improvement foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b543ee593244e4aea61389fc0799b29
http://www.sciencedirect.com/science/article/pii/S0969996107002859
http://www.sciencedirect.com/science/article/pii/S0969996107002859
Autor:
Tatiana Hernandez-Estrada, Kathryn E. Nichol, Lori-Ann Christie, Troy T. Rohn, Elizabeth Head, Veera Vyas
Publikováno v:
The Journal of Neuroscience. 28:3051-3059
Alzheimer's disease (AD) is characterized by the accumulation of plaques containing β-amyloid (Aβ) and neurofibrillary tangles (NFTs) consisting of modified tau. Although Aβ deposition is thought to precede the formation of NFTs in AD, the molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cf62568f1c94803b4f38852034bbc3
https://doi.org/10.1523/jneurosci.5620-07.2008
https://doi.org/10.1523/jneurosci.5620-07.2008
Autor:
Kathryn E. Nichol, M. Harold Laughlin, Elmer M. Price, Judy M. Muller-Delp, Brian J. Philips, Edward M. Curran, Dennis B. Lubahn
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 285:H2150-H2157
Estrogen has been shown to increase endothelium-dependent vasodilation and expression of endothelial nitric oxide (NO) synthase (eNOS); however, the role of estrogen receptors in mediating estrogen effects on endothelial function remains to be elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631a8f7214f43a0a2a92fd54fdf60d5f
https://doi.org/10.1152/ajpheart.00966.2002
https://doi.org/10.1152/ajpheart.00966.2002
Publikováno v:
PLoS ONE
Clobazam (CLB), a 1,5-benzodiazepine (BZD), was FDA-approved in October 2011 for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients 2 years and older. BZDs exert various CNS effects through allosteric modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21553c5019b880a72d1e1f44ba4d439d
http://europepmc.org/articles/PMC3922815
http://europepmc.org/articles/PMC3922815
Publikováno v:
Neurology. 56:S35-S40
Frontotemporal dementia (FTD) is a neurodegenerative disease associated with aging for which the etiology is unclear. Relatively little is known about the pathology of this disease, which has only recently been a topic of investigation for dementia r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04376e572c2c54ab7770d92fdfdee62a
https://doi.org/10.1212/wnl.56.suppl_4.s35
https://doi.org/10.1212/wnl.56.suppl_4.s35
Autor:
Jeanna Winchester, Malcolm B. Dick, Stephen M. Roth, Carl W. Cotman, Joseph C. Wu, Sean P. Deeny, Kathryn E. Nichol
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's Association. 8(4)
Background The possibility that ɛ4 may modulate the effects of fitness in the brain remains controversial. The present exploratory FDG-PET study aimed to better understand the relationship among ɛ4, fitness, and cerebral metabolism in 18 healthy ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebe178831d2e6f9962f8480fea0c6a6
https://pubmed.ncbi.nlm.nih.gov/22226798
https://pubmed.ncbi.nlm.nih.gov/22226798
Autor:
Wayne W. Poon, Anna Parachikova, David H. Cribbs, Kathryn E. Nichol, Carl W. Cotman, Charles G. Glabe
Publikováno v:
Journal of Neuroinflammation, Vol 5, Iss 1, p 13 (2008)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Inflammation is associated with Aβ pathology in Alzheimer's disease (AD) and transgenic AD models. Previously, it has been demonstrated that chronic stimulation of the immune response induces pro-inflammatory cytokines IL-1β and TNF-α w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afa8e52f9c6c17993aee4dc435431d3
http://www.jneuroinflammation.com/content/5/1/13
http://www.jneuroinflammation.com/content/5/1/13
Publikováno v:
Behavioural brain research. 184(2)
If begun early in life, exercise effectively reduces the development of cognitive deficits in transgenic mouse models of Alzheimer's disease (AD). However, the effectiveness of exercise, once the cognitive impairments are established, is not as clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f136329f36df2eee306bab82418dbaf1
https://pubmed.ncbi.nlm.nih.gov/17698211
https://pubmed.ncbi.nlm.nih.gov/17698211
Autor:
Christopher R. Woodman, Robert D. Shipley, Amanda J. LeBlanc, Judy M. Muller-Delp, Rhonda D. Prisby, Kathryn E. Nichol
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2627e252bbf0a5c85fb8ca8bb78b0913
https://doi.org/10.1096/fasebj.20.4.a812-b
https://doi.org/10.1096/fasebj.20.4.a812-b