Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kathryn E. Hudak"'
Autor:
Su I. Chung, Darmood Wei, Luca F. Valle, Grace McKay-Corkum, Ayla O. White, Eun Joo Chung, Kathryn E. Hudak, W. Marston Linehan, Jeffrey Burkeen, Shilpa S. Patil, Bradley T. Scroggins, Deborah Citrin
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 100:344-352
Purpose Specificity protein 1 (SP1) is involved in the transcription of several genes implicated in tumor maintenance. We investigated the effects of mithramycin A (MTA), an inhibitor of SP1 DNA binding, on radiation response. Methods and Materials C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e24f7c2b1c9e5aeb8599b4c628e7d7e
https://doi.org/10.1016/j.ijrobp.2017.09.049
https://doi.org/10.1016/j.ijrobp.2017.09.049
Autor:
Herman F. Staats, Soman N. Abraham, Matthew D. Koci, Elizabeth Ramsburg, Brice E. Barefoot, Moses S. Wanyonyi, Kathryn E. Hudak, Christopher J. Sample
Publikováno v:
Peptides. 48:96-105
Broad-spectrum antiviral drugs are urgently needed to treat individuals infected with new and re-emerging viruses, or with viruses that have developed resistance to antiviral therapies. Mammalian natural host defense peptides (mNHP) are short, usuall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa57a0eec1f709325d59e0d06ac8c04
https://doi.org/10.1016/j.peptides.2013.07.014
https://doi.org/10.1016/j.peptides.2013.07.014
Autor:
Ayla O. White, Jason A. Horton, Jeffrey Burkeen, Bradley T. Scroggins, Deborah Citrin, Eun Joo Chung, Kathryn E. Hudak
Publikováno v:
Stem Cells
Exposure to ionizing radiation (IR) can result in the development of cutaneous fibrosis, for which few therapeutic options exist. We tested the hypothesis that bone marrow-derived mesenchymal stem cells (BMSC) would favorably alter the progression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6227f7b84118cfdbd0b375829767ea
https://doi.org/10.1002/stem.1483
https://doi.org/10.1002/stem.1483
Autor:
Eun Joo Chung, Deborah Citrin, Ayla O. White, Jason A. Horton, Thirumalai R. Ramalingam, Su I. Chung, Bradley T. Scroggins, Joseph R. Arron, Thomas A. Wynn, Kathryn E. Hudak
Publikováno v:
Scientific Reports
Pulmonary fibrosis is a potentially lethal late adverse event of thoracic irradiation. Prior research indicates that unrestrained TGF-β1 and/or type 2 cytokine-driven immune responses promote fibrosis following radiation injury, but the full spectru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8691ca2b3785c7ae0b1e05ce59e6c0c6
https://pubmed.ncbi.nlm.nih.gov/28004808
https://pubmed.ncbi.nlm.nih.gov/28004808
Publikováno v:
Biomarkers in Medicine. 7:827-829
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1bd0195081cacaa93b35b80237f898
https://doi.org/10.2217/bmm.13.123
https://doi.org/10.2217/bmm.13.123
Autor:
Jason A. Horton, Bradley T. Scroggins, Ayla O. White, Deborah Citrin, Eun Joo Chung, Kathryn E. Hudak, Shiva Vaswani
Radiation fibrosis of the lung is a late toxicity of thoracic irradiation. Epidermal growth factor (EGF) signaling has previously been implicated in radiation lung injury. We hypothesized that TGF-α, an EGF receptor ligand, plays a key role in radia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38289bd008fcde5d1b7b54fa30e0149
https://europepmc.org/articles/PMC4169125/
https://europepmc.org/articles/PMC4169125/
Radiation injury is a continuum of complex biological responses. At the time of emergency, multiple methods of technologies are used to monitor radiation exposure levels and measure cellular damage. Identifying markers of exposure and finding unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4be915f0ee6efa72a90c3f912a9ed2d
https://doi.org/10.1016/b978-0-12-404630-6.00039-7
https://doi.org/10.1016/b978-0-12-404630-6.00039-7
Autor:
Angela Thetford, Ayla O. White, Jason A. Horton, Kathryn E. Hudak, James B. Mitchell, Anastasia L. Sowers, Eun Joo Chung, Deborah Citrin
Publikováno v:
Int J Radiat Biol
PURPOSE: Dermal fibrosis is a disabling late toxicity of radiotherapy. Several lines of evidence suggest that overactive signaling via the Platelet-derived growth factor receptor-beta (PDGFR-β) and V-abl Abelson murine leukemia viral oncogene homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a25fc06fa04a6a93d173b4c8da09a2d
https://pubmed.ncbi.nlm.nih.gov/23083077
https://pubmed.ncbi.nlm.nih.gov/23083077
Autor:
Ayla O. White, Jason A. Horton, Eun Joo Chung, Deborah Citrin, Kathryn E. Hudak, Bradley T. Scroggins
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 90:S149-S150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b1f894b6284faee03fcbcea1c65f6c1
https://doi.org/10.1016/j.ijrobp.2014.05.624
https://doi.org/10.1016/j.ijrobp.2014.05.624
Autor:
Albert Haines, Elizabeth Ramsburg, Kathryn E. Hudak, Christopher J. Sample, Thomas B. Kepler, Jeffrey Roach, Allyson L. Walsh
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 444 (2010)
BMC Genomics
BMC Genomics
Background The rate of emergence of human pathogens is steadily increasing; most of these novel agents originate in wildlife. Bats, remarkably, are the natural reservoirs of many of the most pathogenic viruses in humans. There are two bat genome proj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c48f5d71de54740049a3aea21dc125b
http://www.biomedcentral.com/1471-2164/11/444
http://www.biomedcentral.com/1471-2164/11/444