Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children

Autor: Nidhi P, Goyal, Sara B, Rosenthal, Chanod, Nasamran, Cynthia A, Behling, Jorge E, Angeles, Mark H, Fishbein, Kathryn E, Harlow, Ajay K, Jain, Jean P, Molleston, Kimberly P, Newton, Patricia, Ugalde-Nicalo, Stavra A, Xanthankos, Katherine, Yates, Nicholas J, Schork, Kathleen M, Fisch, Jeffrey B, Schwimmer, Donna, Garner

Publikováno v: Hepatology (Baltimore, Md.).

NAFLD is the most common chronic liver disease in children. Large pediatric studies identifying single nucleotide polymorphisms (SNPs) associated with risk and histologic severity of NAFLD are limited. Study aims included investigating SNPs associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56d37e444b40faf93b77bd53d6aea2a
https://pubmed.ncbi.nlm.nih.gov/35560106

Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity

Autor: Janis Durelle, Ethan Z. Sy, Nidhi Goyal, Claude B. Sirlin, Jeffrey B. Schwimmer, Kathryn E. Harlow, Shahrokh Golshan, Michael S. Middleton, Elizabeth L. Yu, Jonathan Hooker, Jorge E. Angeles, Kimberly P. Newton, Mary Catherine Sawh

Publikováno v: Yu, Elizabeth L; Golshan, Shahrokh; Harlow, Kathryn E; Angeles, Jorge E; Durelle, Janis; Goyal, Nidhi P; et al.(2018). Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity.. The Journal of pediatrics. doi: 10.1016/j.jpeds.2018.11.021. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/72r619st

Objectives To determine the prevalence of nonalcoholic fatty liver disease (NAFLD) in children with obesity because current estimates range from 1.7% to 85%. A second objective was to evaluate the diagnostic accuracy of alanine aminotransferase (ALT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6336282f7909a102545194dc4566cbf3
https://doi.org/10.1016/j.jpeds.2018.11.021

Clinical Practice Approach to Nonalcoholic Fatty Liver Disease by Pediatric Gastroenterologists in the United States

Autor: Peter Lee, Stephanie H. Abrams, Lynette A. Gillis, Reham Abdou, Nidhi Goyal, Nirav K. Desai, Kathryn E. Harlow, John F. Pohl, Carol Potter, Warren L. Shapiro, Henry C. Lin, Jennifer C. Arin, Karen F. Murray, Shikha S. Sundaram, Jennifer Panganiban, Marianne Kavan, Elizabeth L. Yu, Sarah A. Faasse, Ajay Jain, Kattayoun Kordy, Timothy A. Hadley, Stavra A. Xanthakos, James A. Proudfoot, Jeffrey B. Schwimmer, Sabina Ali, Kimberly P. Newton, Megan W. Butler, Bryan Rudolph, Naim Alkhouri, Shivali Joshi

Publikováno v: Journal of pediatric gastroenterology and nutrition, vol 68, iss 2
J Pediatr Gastroenterol Nutr

OBJECTIVES: Nonalcoholic fatty liver disease (NAFLD) is common; however, no information is available on how pediatric gastroenterologists in the United States manage NAFLD. Therefore, study objectives were to: (1) understand how pediatric gastroenter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fec6cc95783200c1526fb4682608d9
https://escholarship.org/uc/item/4sc2z8k0

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease

Autor: Kathryn E. Harlow, Jonathan A. Africa, Alan Wells, Patricia H. Belt, Cynthia A. Behling, Ajay K. Jain, Jean P. Molleston, Kimberly P. Newton, Philip Rosenthal, Miriam B. Vos, Stavra A. Xanthakos, Joel E. Lavine, Jeffrey B. Schwimmer, Stephanie H. Abrams, Sarah Barlow, Ryan Himes, Rajesh Krisnamurthy, Leanel Maldonado, Rory Mahabir, April Carr, Kimberlee Bernstein, Kristin Bramlage, Kim Cecil, Stephanie DeVore, Rohit Kohli, Kathleen Lake, Daniel Podberesky, Alex Towbin, Gerald Behr, Jay H. Lefkowitch, Ali Mencin, Elena Reynoso, Adina Alazraki, Rebecca Cleeton, Maria Cordero, Albert Hernandez, Saul Karpen, Jessica Cruz Munos, Nicholas Raviele, Molly Bozic, Oscar W. Cummings, Ann Klipsch, Emily Ragozzino, Kumar Sandrasegaran, Girish Subbarao, Laura Walker, Kimberly Kafka, Ann Scheimann, Joy Ito, Mark H. Fishbein, Saeed Mohammad, Cynthia Rigsby, Lisa Sharda, Peter F. Whitington, Theresa Cattoor, Jose Derdoy, Janet Freebersyser, Debra King, Jinping Lai, Pat Osmack, Joan Siegner, Susan Stewart, Susan Torretta, Kristina Wriston, Susan S. Baker, Diana Lopez-Graham, Sonja Williams, Lixin Zhu, Hannah Awai, Craig Bross, Jennifer Collins, Janis Durelle, Michael Middleton, Melissa Paiz, Claude Sirlin, Patricia Ugalde-Nicalo, Mariana Dominguez Villarreal, Bradley Aouizerat, Jesse Courtier, Linda D. Ferrell, Natasha Feier, Ryan Gill, Camille Langlois, Emily Rothbaum Perito, Patrika Tsai, Kara Cooper, Simon Horslen, Evelyn Hsu, Karen Murray, Randolph Otto, Matthew Yeh, Melissa Young, Elizabeth M. Brunt, Kathryn Fowler, David E. Kleiner, Sherry Brown, Edward C. Doo, Jay H. Hoofnagle, Patricia R. Robuck, Averell Sherker, Rebecca Torrance, Jeanne M. Clark, Michele Donithan, Erin Hallinan, Milana Isaacson, Kevin P. May, Laura Miriel, Alice Sternberg, James Tonascia, Mark Van Natta, Laura Wilson, Katherine Yates

Publikováno v: The Journal of Pediatrics. 198:76-83.e2

OBJECTIVE:To determine the percentage of children with nonalcoholic fatty liver disease (NAFLD) in whom intervention for low-density lipoprotein cholesterol or triglycerides was indicated based on National Heart, Lung, and Blood Institute guidelines.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93414becfa69c72837d3a5dbc5977653
https://doi.org/10.1016/j.jpeds.2018.02.038