Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathryn C. Allaway"'
Autor:
Kathryn C Allaway, William Muñoz, Robin Tremblay, Mia Sherer, Jacob Herron, Bernardo Rudy, Robert Machold, Gordon Fishell
Publikováno v:
eLife, Vol 9 (2020)
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely. However, recent studies have r
Externí odkaz:
https://doaj.org/article/76d52b0e73f54be6840b1c899dd26c14
Autor:
Gabrielle Pouchelon, Josselyn Vergara, Justin McMahon, Bram L. Gorissen, Jessica D. Lin, Douglas Vormstein-Schneider, Jason L. Niehaus, Timothy J. Burbridge, Jason C. Wester, Mia Sherer, Marian Fernandez-Otero, Kathryn C. Allaway, Kenneth Pelkey, Ramesh Chittajallu, Chris J. McBain, Melina Fan, Jason S. Nasse, Gregg A. Wildenberg, Gordon Fishell, Jordane Dimidschstein
Publikováno v:
Cell reports methods. 2(6)
The ability to precisely control transgene expression is essential for basic research and clinical applications. Adeno-associated viruses (AAVs) are non-pathogenic and can be used to drive stable expression in virtually any tissue, cell type, or spec
Autor:
Douglas Vormstein-Schneider, John V. Reynolds, Zhanyan Fu, Xiaoqing Yuan, Qiangge Zhang, Jared B. Smith, Giuseppe A. Saldi, Vanessa Sanchez, Jitendra Sharma, Gates Schneider, Renata Batista-Brito, Josselyn Vergara, Kareem A. Zaghloul, Jessica Lin, Orrin Devinsky, Timothy Burbridge, Kathryn C. Allaway, Leena A. Ibrahim, Sofia Sakopoulos, Guoping Feng, Emilia Favuzzi, Jordane Dimidschstein, Bram L. Gorissen, Tom P. Franken, Baolin Guo, Gord Fishell, Mario A. Arias-Garcia, Shuhan Huang, Bernardo L. Sabatini, Ramesh Chittajallu, Olivia Stevenson, Kenneth A. Pelkey, Chris J. McBain, Ian Vogel, Qing Xu, Ehsan Sabri, Lihua Guo, Kevin J. M astro
Publikováno v:
Nature Neuroscience. 23:1629-1636
Recent success in identifying gene-regulatory elements in the context of recombinant adeno-associated virus vectors has enabled cell-type-restricted gene expression. However, within the cerebral cortex these tools are largely limited to broad classes
Autor:
Mia Sherer, William Muñoz, Robin Tremblay, Kathryn C. Allaway, Gord Fishell, Robert Machold, Jacob Herron, Bernardo Rudy
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely. However, recent studies have r
Autor:
Bernardo Rudy, Gord Fishell, William Muñoz, Robin Tremblay, Kathryn C. Allaway, Mia Sherer, Robert Machold, Jacob Herron
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely. However, recent studies have r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d966267654fd4126d40495204c704d3e
https://doi.org/10.1101/2020.10.08.331223
https://doi.org/10.1101/2020.10.08.331223
Autor:
Mariano I. Gabitto, Giuseppe A. Saldi, Rachel C. Bandler, Gord Fishell, Richard Bonneau, Orly Wapinski, Chen Yu Wang, Kathryn C. Allaway, Sherry Jingjing Wu
Publikováno v:
Nature
One of the hallmarks of the cerebral cortex is the extreme diversity of interneurons1–3. The two largest subtypes of cortical interneurons, parvalbumin- and somatostatin-positive cells, are morphologically and functionally distinct in adulthood but
Autor:
Nicholas Carriero, Richard Bonneau, Kathryn C. Allaway, Orly L. Wapinski, Mariano I. Gabitto, Gordon Fishell, Anders Rasmussen
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
ATAC-seq has become a leading technology for probing the chromatin landscape of single and aggregated cells. Distilling functional regions from ATAC-seq presents diverse analysis challenges. Methods commonly used to analyze chromatin accessibility da
Autor:
Xavier H. Jaglin, Rahul Satija, Christian Mayer, Robert Machold, Renata Batista Brito, Andrew Butler, Christoph Hafemeister, Rachel C. Bandler, Kathryn C. Allaway, Gord Fishell
Publikováno v:
Nature
Diverse subsets of cortical interneurons play a particularly important role in the stability of the neural circuits underlying cognitive and higher order brain functions, yet our understanding of how this diversity is generated is far from complete.
Autor:
Kathryn C. Allaway, Robert Machold
Publikováno v:
Developmental Biology. 421:1-7
Striatal cholinergic interneurons and basal forebrain cholinergic projection neurons, which together comprise the forebrain cholinergic system, regulate attention, memory, reward pathways, and motor activity through the neuromodulation of multiple br