Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kathryn Ana Bortolim Simão da Silva"'
Autor:
João B. Calixto, Lilian W. Rocha, Nara Lins Meira Quintão, Gislaine Francieli da Silva, Marianne N. Manjavachi, Maria M. Campos, Ana Flavia Paszcuk, Kathryn Ana Bortolim Simão da Silva, Allisson Freire Bento
Publikováno v:
Inflammopharmacology. 27:573-586
Tumour necrosis factor (TNF) and kinins have been associated with neuropathic pain-like behaviour in numerous animal models. However, the way that they interact to cause neuron sensitisation remains unclear. This study assessed the interaction of kin
Autor:
Gislaine Francieli da Silva, João B. Calixto, Ana Flavia Paszcuk, Lilian W. Rocha, Maria M. Campos, Marianne N. Manjavachi, Allisson Freire Bento, Nara Lins Meira Quintão, Kathryn Ana Bortolim Simão da Silva
Publikováno v:
Inflammopharmacology. 27:587-588
Autor:
Gabriela C. Segat, Kathryn Ana Bortolim Simão da Silva, Emerson Marcelo Motta, Maíra A. Bicca, L.F. Pianowski, Robson Costa, J B Calixto, Rafael C. Dutra
Publikováno v:
Neuroscience. 303:126-137
Evidences suggest protein kinase C epsilon (PKCε) activation is involved in both inflammatory and neuropathic pains. We have previously shown that tetracyclic triterpene euphol produces antinociception in different models of persistent pain, an acti
Autor:
Luiz Francisco Pianowski, Ana Flavia Paszcuk, Rafael C. Dutra, Allison Freire Bento, Kathryn Ana Bortolim Simão da Silva, Flavia Carla Meotti, J B Calixto, Rodrigo Marcon
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Persistent pains associated with inflammatory and neuropathic states are prevalent and debilitating diseases, which still remain without a safe and adequate treatment. Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological pro
Autor:
J B Calixto, Eduardo Luiz Santos da Silva, Flavia Carla Meotti, Kathryn Ana Bortolim Simão da Silva, Ana Flavia Paszcuk, Giselle F. Passos, Allison Freire Bento
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
In this study, we report that α,β-amyrin, a plant-derived pentacyclic triterpene, reduced persistent inflammatory and neuropathic hyperalgesia in mice by a direct activation of the CB(1) and CB(2) cannabinoid receptors (CB(1)R and CB(2)R). The oral
Autor:
L.F. Pianowski, RR Dutra, EM Motta, Kathryn Ana Bortolim Simão da Silva, AF Paszcuk, Rodrigo Marcon, João B. Calixto, Allisson Freire Bento, FC Meiotti
Publikováno v:
Planta Medica. 77
Autor:
Vanderlan da Silva Bolzani, Marianne N. Manjavachi, Marcos Pivatto, Ana Flavia Paszcuk, João B. Calixto, Kathryn Ana Bortolim Simão da Silva, Claudio Viegas
Publikováno v:
Neuropharmacology. 62(2)
Natural products have been revealed as relevant sources of therapeutic agents including those for the management of pain states. In this study, the anti-nociceptive and anti-inflammatory effects of (-)-cassine, isolated from Senna spectabilis were ev
Autor:
Filipe S. Duarte, Jarbas Mota Siqueira, Paulo César Leal, Rodrigo Medeiros, Kathryn Ana Bortolim Simão da Silva, Rui Daniel Prediger, Cláudia P. Figueiredo, David H. Cribbs, João B. Calixto, Giselle F. Passos
Publikováno v:
Alzheimer's & Dementia. 6
Autor:
Maria M. Campos, Rafael C. Dutra, João B. Calixto, Ana Flavia Paszcuk, Nara Lins Meira Quintão, Kathryn Ana Bortolim Simão da Silva
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24034 (2011)
PLoS ONE
PLoS ONE
Background Many studies have shown the antinociceptive effects of cannabinoid (CB) agonists in different models of pain. Herein, we have investigated their relevance in neuropathic pain induced by brachial plexus avulsion (BPA) in mice. Methodology/P