Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kathryn A. Swanson"'
Autor:
Kayla L. Nguyen, Ishaan J. Bhatt, Shruti Gupta, Nazaf Showkat, Kathryn A. Swanson, Roman Fischer, Roland E. Kontermann, Klaus Pfizenmaier, Valerie Bracchi-Ricard, John R. Bethea
Publikováno v:
Brain Research Bulletin, Vol 207, Iss , Pp 110885- (2024)
Multiple sclerosis (MS), a demyelinating autoimmune disease of the central nervous system (CNS), predominately affects females compared to males. Tumor necrosis factor (TNF), a pro-inflammatory cytokine, signaling through TNF receptor 1 contributes t
Externí odkaz:
https://doaj.org/article/667057d00d2a42bdb40ed215236bb75d
Autor:
Roland E. Kontermann, George F. Martinez, Valerie Bracchi-Ricard, Tanja Padutsch, Klaus Pfizenmaier, John R. Bethea, Elizabeth K Pruzinsky, Tania del Rivero, Roman Fischer, Michael J Rosalino, Kathryn A Swanson, Maksim Sendetski, Niky Delguercio
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tumor necrosis factor (TNF) is a cytokine that induces signaling via two receptors, TNFR1 and TNFR2. TNF signaling via TNFR1 contributes to development and maintenance of neuropathic pain. Here, we show that TNFR2 is essential for recove
Autor:
Roman Fischer, Kathryn A Swanson, Lesley Probert, Ulrich L. M. Eisel, John R. Bethea, Valentina Pegoretti
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
CNS inflammation is a major driver of MS pathology. Differential immune responses, including the adaptive and the innate immune system, are observed at various stages of MS and drive disease development and progression. Next to these immune-mediated
Autor:
Eugene Mironets, Thomas S. Truglio, Kathryn A Swanson, Micaela L. O’Reilly, Veronica J. Tom, Tatiana M. Saltos, John R. Bethea, Valerie Bracchi-Ricard, Roman Fischer
Publikováno v:
J Neurosci
Spinal cord injury (SCI) disrupts critical physiological systems, including the cardiovascular and immune system. Plasticity of spinal circuits below the injury results in abnormal, heightened sympathetic responses, such as extreme, sudden hypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8885a1da5cf6828a401aa4ec2c99bc13
https://europepmc.org/articles/PMC6948947/
https://europepmc.org/articles/PMC6948947/
Publikováno v:
Pain. 160(4)
Tumor necrosis factor (TNF) is a proinflammatory cytokine, which is involved in physiological and pathological processes and has been found to be crucial for pain development. In the current study, we were interested in the effects of blocking Tumor
Autor:
Valerie Bracchi-Ricard, Roman Fischer, Ishaan J. Bhatt, Kathryn A Swanson, John R. Bethea, Laura Oakley, Richard J. Smeyne, Kayla L. Murphy
Publikováno v:
Exp Neurol
Multiple sclerosis is an autoimmune disorder of the central nervous system (CNS) characterized by locomotor impairments, cognitive deficits, affective disorders, and chronic pain. Females are predominately affected by MS compared to males and develop
Autor:
Weihua Cai, Mark Lay, Yuan Xiang Tao, Xinying Guo, Justin Burdge, John R. Bethea, Jessica M Jones, Xinzhong Dong, Roman Fischer, Ishmail Abdus-Saboor, Wenqin Luo, Long Ding, Minghong Ma, Peter Dong, Nathan T. Fried, Kathryn A Swanson
Publikováno v:
Cell reports
SUMMARY Rodents are the main model systems for pain research, but determining their pain state is challenging. To develop an objective method to assess pain sensation in mice, we adopt high-speed videography to capture sub-second behavioral features
Autor:
Constance Tom Noguchi, Kathryn M. Swanson, Ji Won Park, Soumyadeep Dey, Barbora Piknova, Alan N. Schechter
Publikováno v:
Nitric oxide : biology and chemistry. 47
The nitric oxide synthase (NOS) family of enzymes form nitric oxide (NO) from arginine in the presence of oxygen. At reduced oxygen availability NO is also generated from nitrate in a two step process by bacterial and mammalian molybdopterin proteins
Publikováno v:
Free Radical Biology and Medicine. 76:S17-S18
Publikováno v:
Free Radical Biology and Medicine. 53:S185