Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kathryn A. Salvati"'
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102558- (2021)
Summary: STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, and epilepsy. While neural networks are known to operate at a critical state in the healthy brain, network behavior during pathological epilep
Externí odkaz:
https://doaj.org/article/1b3fd895552e4e51ab633cc03b8ad321
Autor:
Kathryn A Salvati, George MPR Souza, Adam C Lu, Matthew L Ritger, Patrice Guyenet, Stephen B Abbott, Mark P Beenhakker
Publikováno v:
eLife, Vol 11 (2022)
Hyperventilation reliably provokes seizures in patients diagnosed with absence epilepsy. Despite this predictable patient response, the mechanisms that enable hyperventilation to powerfully activate absence seizure-generating circuits remain entirely
Externí odkaz:
https://doaj.org/article/cc56f6959ce24050beadb2435bad5e11
Autor:
John S. Lazo, George S. Bloom, Elizabeth R. Sharlow, Anna J. Mendelson, Porterfield, Kathryn A. Salvati, Mark P. Beenhakker, Mingledorff G, Danielle C. Llaneza
Neurogenesis is a complex process encompassing neuronal progenitor cell expansion/proliferation and differentiation, followed by neuron maturation. In vivo models are most commonly used to study neurogenesis; however, human induced pluripotent stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0087eb002e7550fa3bd99d3f6ea96712
https://doi.org/10.1101/2021.08.17.456634
https://doi.org/10.1101/2021.08.17.456634
Autor:
Patrice G. Guyenet, Stephen B. G. Abbott, Mark P. Beenhakker, George M. P. R. Souza, Kathryn A. Salvati, Matthew Lonergan Ritger, Adam C Lu
Publikováno v:
eLife. 11
Hyperventilation reliably provokes seizures in patients diagnosed with absence epilepsy. Despite this predictable patient response, the mechanisms that enable hyperventilation to powerfully activate absence seizure-generating circuits remain entirely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd508df443736fee01cacba404bef55
https://pubmed.ncbi.nlm.nih.gov/34982032
https://pubmed.ncbi.nlm.nih.gov/34982032
Autor:
Mark P. Beenhakker, Casey D. Gailey, Eric J. Wang, Ashley J. Mason, Zheng Fu, Kathryn A. Salvati
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8875, p 8875 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
CILK1 (ciliogenesis associated kinase 1)/ICK (intestinal cell kinase) is a highly conserved protein kinase that regulates primary cilia structure and function. CILK1 mutations cause a wide spectrum of human diseases collectively called ciliopathies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374393361f1c4f49f4be5700c3756216
https://www.mdpi.com/1422-0067/22/16/8875
https://www.mdpi.com/1422-0067/22/16/8875
Autor:
Kathryn A, Salvati, Ashley J, Mason, Casey D, Gailey, Eric J, Wang, Zheng, Fu, Mark P, Beenhakker
Publikováno v:
International Journal of Molecular Sciences
CILK1 (ciliogenesis associated kinase 1)/ICK (intestinal cell kinase) is a highly conserved protein kinase that regulates primary cilia structure and function. CILK1 mutations cause a wide spectrum of human diseases collectively called ciliopathies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bf67b6467a03faa895fb5f8567cb92e
https://pubmed.ncbi.nlm.nih.gov/34445580
https://pubmed.ncbi.nlm.nih.gov/34445580
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102558-(2021)
iScience
iScience
Summary STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, and epilepsy. While neural networks are known to operate at a critical state in the healthy brain, network behavior during pathological epilept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8506e4fb95b65f3ced13a0e4489e9852
http://www.sciencedirect.com/science/article/pii/S2589004221005265
http://www.sciencedirect.com/science/article/pii/S2589004221005265
Autor:
Mark P. Beenhakker, Kathryn A. Salvati
Publikováno v:
J Neurosci
Epilepsy Currents
Epilepsy Currents
The epilepsy-linked gene SV2A, has a number of potential roles in the synaptic vesicle (SV) life cycle. However, how loss of SV2A function translates into presynaptic dysfunction and ultimately seizure activity is still undetermined. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616af812590736816264dfff5cf96016
https://pubmed.ncbi.nlm.nih.gov/32341095
https://pubmed.ncbi.nlm.nih.gov/32341095
Autor:
Kathryn A Salvati, Matthew L Ritger, Pasha A Davoudian, Finnegan O’Dell, Daniel R Wyskiel, George M P R Souza, Adam C Lu, Edward Perez-Reyes, Joshua C Drake, Zhen Yan, Mark P Beenhakker
Publikováno v:
Brain : a journal of neurology, vol 145, iss 7
Metabolism regulates neuronal activity and modulates the occurrence of epileptic seizures. Here, using two rodent models of absence epilepsy, we show that hypoglycaemia increases the occurrence of spike-wave seizures. We then show that selectively di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32274bd8a7383afcab88c1ad0638f881
https://pubmed.ncbi.nlm.nih.gov/35134125
https://pubmed.ncbi.nlm.nih.gov/35134125