Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathryn A. Hijazi"'
Autor:
Alexey L. Arkov, Frances T. Pagel, Song Q. Zhao, Wenbing Xu, Kathryn A. Hijazi, Emanuel J. Murgola
Publikováno v:
Biochemistry and Cell Biology. 73:925-931
To screen for ribosomal RNA mutants defective in peptide chain termination, we have been looking for rRNA mutants that exhibit different patterns of suppression of nonsense mutations and that do not suppress missense mutations at the same positions i
Autor:
B.H. Mims, D. Brechemier-Baey, P.M. Sörensen, Kathryn A. Hijazi, Emanuel J. Murgola, Frances T. Pagel, Richard H. Buckingham
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1050:259-262
The base sequence around nonsense codons affects the efficiency of nonsense codon suppression. Published data, comparing different nonsense sites in a mRNA, implicate the two bases downstream of the nonsense codon as major determinants of suppression
Publikováno v:
Journal of molecular biology. 267(5)
RNA sites that contain unpaired or mismatched nucleotides can be interaction sites for other macromolecules. C1054, a virtually universally conserved nucleotide in the 16 S (small subunit) ribosomal RNA of Escherichia coli, is part of a highly conser
Publikováno v:
Biochimie. 72(12)
A modified assay has been devised for the physiological reaction, indole-3-glycerol phosphate to Trp, of the enzyme tryptophan synthetase. The assay may be applied to crude bacterial extracts, and is based on the measurement of incorporation of radio
Publikováno v:
Biochimie. 71(6)
This paper describes a novel mechanism for reversion of nonsense mutations in the trpA gene of Escherichia coli. This mechanism, deletion of the nonsense codon, was discovered in the course of selecting for missense revertants of trpA(UGA211) and for
Publikováno v:
Journal of molecular biology. 175(1)
After our first observation of codon context effects in missense suppression (Murgola & Pagel, 1983), we measured the suppression of missense mutations at two positions in trpA in Escherichia coli. The suppressible codons in the trpA messenger RNA we
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 80(16)
In a previous publication, an unusual UGG-reading missense suppressor caused by insertion of an extra adenylate residue in the anticodon loop of an Escherichia coli glycine tRNA was described. In this study, we provide in vivo evidence that the addit
Autor:
Kathryn A. Hijazi, Emanuel J. Murgola
Publikováno v:
Moleculargeneral genetics : MGG. 191(1)
Previous studies have demonstrated many amino acid and codon substitutions at position 211 of the alpha chain of tryptophan synthetase of Escherichia coli. In order to extend our studies on suppressor tRNAs and, in general, on accuracy in the transla
Publikováno v:
Journal of Cellular Biochemistry; Feb1991 Supplement 15D, Vol. 47, p149-221, 73p
Publikováno v:
Molecular & General Genetics MGG; 1984, Vol. 193 Issue 1, p76-81, 6p