Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Kathryn A. Elliget"'
1
H-ras-transformed NRK-52E renal epithelial cells have altered growth, morphology, and cytoskeletal structure that correlates with renal cell carcinoma in vivo
Autor: Carolyn J. M. Best, P. C. Phelps, Ronald L. Merriman, George G. Boder, Lee R. Tanzer, Kathryn A. Elliget, Benjamin F. Trump
Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 35:205-214
We studied the effect of the ras oncogene on the growth kinetics, morphology, cytoskeletal structure, and tumorigenicity of the widely used NRK-52E rat kidney epithelial cell line and two H-ras oncogene-transformed cell lines, H/1.2-NRK-52E (H/1.2) a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c059f25d413127ded7cc451f35dd7702
https://doi.org/10.1007/s11626-999-0028-2
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2
Cytosolic Ca2+ Elevation and Calpain Inhibitors in HgCl2 Injury to Rat Kidney Proximal Tubule Epithelial Cells
Autor: Patricia C. Phelps, Kathryn A. Elliget, Benjamin F. Trump
Publikováno v: Pathobiology. 62:298-310
This study assessed HgCl2 injury to proximal tubule epithelial cells as it relates to the concentration of ionized cytosolic Ca2+ ([Ca2+]i) elevation and activation of calpains. Experiments in high and low extracellular Ca2+ concentration ([Ca2+]e) w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aaf2e0d3c1352b3c7203e163156267d3
https://doi.org/10.1159/000163923
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4
Nephrotoxicity in vitro: Role of ion deregulation in signal transduction following injury-Studies utilizing digital imaging fluorescence microscopy
Autor: P. C. Phelps, Benjamin F. Trump, Kathryn A. Elliget, Irene K. Berezesky, M.A. Smith
Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 4(4-5)
Over the years, many approaches have been utilized for studying in vitro toxicity in the kidney. These have included the use of isolated perfused kidneys, renal slices, isolated nephron explants and cultured tubular epithelium. Currently, in vitro sy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4797cfbd94646d296fa1003c1e6193
https://pubmed.ncbi.nlm.nih.gov/20702205
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5
Long-term culture of human esophageal explants and cells
Autor: James H. Resau, John R. Cottrell, Si min Zhu, Kathryn A. Elliget, Hsiang Kuang Lee, P. C. Phelps, Eric A. Hudson, Duane Smoot
Publikováno v: Cytotechnology. 3:61-73
Human esophageal epithelium obtained from intermediate autopsies (less than 12 h) was maintained as cell and explant cultures. In order to develop a serum-free, defined media culture model, several medias and additives were evaluated. The viability a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e904a11891553baa038ee21798e7e669
https://doi.org/10.1007/bf00365267
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6
Primary cultures of normal rat kidney proximal tubule epithelial cells for studies of renal cell injury
Autor: Benjamin F. Trump, Kathryn A. Elliget
Publikováno v: In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. (9)
Normal rat kidney proximal tubule epithelial cell cultures were obtained by collagenase digestion of cortex and studied for 10 days. To assess the purity of the seeding suspension, we histochemically demonstrated gamma-glutamyltranspeptidase in great
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae179f9068f69652a8010f769a76b060
https://pubmed.ncbi.nlm.nih.gov/1717431
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7
Relation between toxicity and carcinogenesis in the kidney: an heuristic hypothesis
Autor: Atsuhiko Maki, T. W. Jones, Kathryn A. Elliget, Benjamin F. Trump, Irene K. Berezesky, Mary W. Smith, P. C. Phelps
Publikováno v: Renal failure. 12(3)
Cellular toxicity and cellular carcinogenesis are closely linked. In the kidney, this relationship has been emphasized by the recent discovery of a number ofputatively non-mutagenic chemicals that result in acute and chronic toxicity and ultimately i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae28fa6574e24a697115e5661c847e3c
https://pubmed.ncbi.nlm.nih.gov/2287771
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9
Preparation of primary cultures of rat hepatocytes suitable for in vitro toxicity testing
Autor: Gerald J. Kolaja, Kathryn A. Elliget
Publikováno v: Journal of Tissue Culture Methods. 8:1-6
A procedure for preparing and culturing rat hepatocytes is described. The liver tissue is dissociated using collagenase and hyaluronidase. Individual cells are isolated by filtration through sieves followed by low speed centrifugation. The resulting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b4807542e1e854dda941c285cdaa25d
https://doi.org/10.1007/bf01834627
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10
Purification of neonatal rat cardiac cells by centrifugal elutriation
Autor: Diane K. Rosnick, Kathryn A. Elliget, Roger G. Ulrich
Publikováno v: Journal of Tissue Culture Methods. 11:217-221
A method utilizing centrifugal elutriation to obtain a highly purified (95 ± 2% after 3 d in culture) preparation of beating cardiac myocytes from enzyme-dissociated neonatal rat heart is described. An additional fraction enriched for nonmuscle cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99a0e6c5f0395ba17758b8990f78a858
https://doi.org/10.1007/bf01407317
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