Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Kathryn A. Chung"'
Autor:
Rosie Morris, Douglas N. Martini, Katrina Ramsey, Valerie E. Kelly, Katrijn Smulders, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated wi
Externí odkaz:
https://doaj.org/article/56b617566f02418bacfaf0ca87b711a1
Autor:
Rosie Morris, Douglas N. Martini, Valerie E. Kelly, Katrijn Smulders, Katrina Ramsey, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100201- (2023)
Background: Gait and balance impairments are among the most troublesome and heterogeneous in Parkinson’s disease (PD). This heterogeneity may, in part, reflect genetic variation. The apolipoprotein E (APOE) gene has three major allelic variants (ε
Externí odkaz:
https://doaj.org/article/3cac717a7a5542b3a906ea0c2ee206cc
Autor:
Hojoong M. Kim, Carter Nazor, Cyrus P. Zabetian, Joseph F. Quinn, Kathryn A. Chung, Amie L. Hiller, Shu-Ching Hu, James B. Leverenz, Thomas J. Montine, Karen L. Edwards, Brenna Cholerton
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 1, Iss , Pp 91-97 (2019)
Introduction: Cognitive impairment is a common complication of Parkinson's disease (PD) and identifying risk factors for progression to Parkinson's disease dementia (PDD) is important. However, little research has been done comparing the utility of c
Externí odkaz:
https://doaj.org/article/2d3a5cedd1d543278e74ba27618d825f
Autor:
Nathan Hwangbo, Xinyu Zhang, Daniel Raftery, Haiwei Gu, Shu-Ching Hu, Thomas J. Montine, Joseph F. Quinn, Kathryn A. Chung, Amie L. Hiller, Dongfang Wang, Qiang Fei, Lisa Bettcher, Cyrus P. Zabetian, Elaine R. Peskind, Ge Li, Daniel E. L. Promislow, Marie Y. Davis, Alexander Franks
Publikováno v:
Metabolites, Vol 12, Iss 4, p 277 (2022)
In recent years, metabolomics has been used as a powerful tool to better understand the physiology of neurodegenerative diseases and identify potential biomarkers for progression. We used targeted and untargeted aqueous, and lipidomic profiles of the
Externí odkaz:
https://doaj.org/article/12d1af88227d4f6dab2f61bf4e53a250
Autor:
Douglas N. Martini, Rosie Morris, Valerie E. Kelly, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, John Oakley, Kathleen Poston, Ignacio F. Mata, Karen L. Edwards, Jodi A. Lapidus, Thomas J. Grabowski, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Mobility and sensorimotor inhibition impairments are heterogeneous in Parkinson's disease (PD). Genetics may contribute to this heterogeneity since the apolipoprotein (APOE) ε4 allele and glucocerebrosidase (GBA) gene variants have been
Externí odkaz:
https://doaj.org/article/336eb63f38414cdc9467ccea733af154
Autor:
Joseph F. Quinn, Alexander Pantelyat, Lu Tian, Karen L. Edwards, Thomas J. Montine, Liana S. Rosenthal, Brenna Cholerton, Amie L. Hiller, Kathryn A. Chung, Cyrus P. Zabetian, Ted M. Dawson, Laurice Yang, Shu Ching Hu, Kathleen L. Poston
Publikováno v:
Journal of clinical and experimental neuropsychology, vol 43, iss 5
J Clin Exp Neuropsychol
J Clin Exp Neuropsychol
Introduction: Parkinson's disease (PD) is associated with a range of cognitive deficits. Few studies have carefully examined the subtle impacts of PD on cognition among patients who do not meet formal criteria for MCI or dementia. The aim of the curr
Autor:
Cyrus P. Zabetian, Jodi Lapidus, John C. Oakley, Tara M. Madhyastha, Thomas J. Montine, Katrina Ramsey, Brenna Cholerton, Rosie Morris, Thomas J. Grabowski, Douglas N. Martini, Fay B. Horak, Amie L. Hiller, Shu Ching Hu, Joseph F. Quinn, Karen L. Edwards, Kathryn A. Chung
Publikováno v:
J Gerontol A Biol Sci Med Sci
Background Reduced cortical sensorimotor inhibition is associated with mobility and cognitive impairments in people with Parkinson’s disease (PD) and older adults (OAs). However, there is a lack of clarity regarding the relationships among sensorim
Autor:
Kathryn A. Chung, Ronald F. Pfeiffer
Publikováno v:
Clinical Autonomic Research. 31:77-99
Interest in gastrointestinal dysfunction in Parkinson’s disease has blossomed over the past 30 years and has generated a wealth of investigation into this non-motor aspect of the disorder, research that has encompassed its pathophysiology, its clin
Autor:
Franks, Nathan Hwangbo, Xinyu Zhang, Daniel Raftery, Haiwei Gu, Shu-Ching Hu, Thomas J. Montine, Joseph F. Quinn, Kathryn A. Chung, Amie L. Hiller, Dongfang Wang, Qiang Fei, Lisa Bettcher, Cyrus P. Zabetian, Elaine R. Peskind, Ge Li, Daniel E. L. Promislow, Marie Y. Davis, Alexander
Publikováno v:
Metabolites; Volume 12; Issue 4; Pages: 277
In recent years, metabolomics has been used as a powerful tool to better understand the physiology of neurodegenerative diseases and identify potential biomarkers for progression. We used targeted and untargeted aqueous, and lipidomic profiles of the
Autor:
Kathleen L. Poston, Ignacio F. Mata, Joseph F. Quinn, Karen L. Edwards, Amie L. Hiller, Nima Aghaeepour, Cyrus P. Zabetian, Thanaphong Phongpreecha, Kathryn A. Chung, Shu Ching Hu, Lu Tian, Brenna Cholerton, Thomas J. Montine
Publikováno v:
npj Parkinson's Disease, Vol 6, Iss 1, Pp 1-10 (2020)
NPJ Parkinson's Disease
NPJ Parkinson's Disease
Cognitive impairment in Parkinson’s disease (PD) is pervasive with potentially devastating effects. Identification of those at risk for cognitive decline is vital to identify and implement appropriate interventions. Robust multivariate approaches,