Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kathryn A. Carbajal"'
Autor:
Katherine H. Schreiber, Sebastian I. Arriola Apelo, Deyang Yu, Jacqueline A. Brinkman, Michael C. Velarde, Faizan A. Syed, Chen-Yu Liao, Emma L. Baar, Kathryn A. Carbajal, Dawn S. Sherman, Denise Ortiz, Regina Brunauer, Shany E. Yang, Stelios T. Tzannis, Brian K. Kennedy, Dudley W. Lamming
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Rapamycin extends lifespan in model organisms by targeting mTORC1, but exerts off-target side effects via inhibition of mTORC2. Here, the authors report the identification of a selective mTORC1 inhibitor, and show that it inhibits mTORC1 activity bot
Externí odkaz:
https://doaj.org/article/62fe1b728b0148059e306c8857df6c69
Autor:
Leigh Ann Simmons, Jennifer E Phipps, Mackenzie Whipps, Paige Smith, Kathryn A Carbajal, Courtney Overstreet, Jennifer McLaughlin, Koen De Lombaert, Devon Noonan
Clinical trials worldwide were disrupted when the COVID-19 pandemic began in early 2020. Most intervention trials moved to some form of remote implementation due to restrictions on in-person research activities. Although the proportion of remote tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3065d68b9b1d0f344a1c45ff14baaf14
https://escholarship.org/uc/item/4g09f6sq
https://escholarship.org/uc/item/4g09f6sq
Autor:
Schaid, Michelle E. Kimple, Haley Wienkes, Austin Reuter, Darby C. Peter, Kathryn A. Carbajal, Rachel J. Fenske
The mechanisms that underlie the β-cell pathophysiology of Type 1 Diabetes (T1D) are not fully understood. Our group has defined the unique heterotrimeric G protein alpha-subunit, Gαz, as a key negative regulator of β-cell signal transduction path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a350f9cf18378e834e7b86d4415f3b2
https://doi.org/10.1101/2021.02.08.430304
https://doi.org/10.1101/2021.02.08.430304
Autor:
Mark Cadena, Quincy Eckert Harenda, Michelle E. Kimple, Harpreet K. Brar, Erin Laundre, Jaclyn A. Wisinski, Haley Wienkes, Rachel J. Fenske, Feyza Engin, Kathryn A. Carbajal, Jinjin Cai, Allison L. Brill, Timothy E. Graham, Michael D. Schaid, Nathan A. Truchan
Publikováno v:
Endocrinology. 158:1645-1658
The α-subunit of the heterotrimeric Gz protein, Gαz, promotes β-cell death and inhibits β-cell replication when pancreatic islets are challenged by stressors. Thus, we hypothesized that loss of Gαz protein would preserve functional β-cell mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e38097c30271c3b225bcbcfa7ad6d26
https://doi.org/10.1210/en.2016-1700
https://doi.org/10.1210/en.2016-1700
Autor:
Michelle E. Kimple, Kathryn A. Carbajal, Michael D. Schaid, Austin Reuter, Jaclyn A. Wisinski
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64eed66ad57aabfd71dd19d6ce08ca40
https://doi.org/10.1096/fasebj.2019.33.1_supplement.809.3
https://doi.org/10.1096/fasebj.2019.33.1_supplement.809.3
Autor:
Kathryn A. Carbajal, Darby C. Peter, Michelle E. Kimple, Rachel J. Fenske, Austin Reuter, Haley Wienkes
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b3dccb6b7c07c35bbb3a05a3c0c41ba
https://doi.org/10.1096/fasebj.2019.33.1_supplement.680.14
https://doi.org/10.1096/fasebj.2019.33.1_supplement.680.14
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8c9f72307c62d8a134ff55974e4d8d
https://doi.org/10.1096/fasebj.2019.33.1_supplement.514.16
https://doi.org/10.1096/fasebj.2019.33.1_supplement.514.16
Autor:
Grant M. Kelly, Kathryn A. Carbajal, Dudley W. Lamming, Michelle E. Kimple, Erin Guthery, Shannon J. Gallagher, Allison L. Brill, Joshua C. Neuman, Darby C. Peter, Cara L Green, Molly L. Wehner, Michael D. Schaid, Austin Reuter, Jeffrey M. Harrington
Publikováno v:
The Journal of Biological Chemistry
The inhibitory G protein alpha-subunit (Gαz) is an important modulator of beta-cell function. Full-body Gαz-null mice are protected from hyperglycemia and glucose intolerance after long-term high-fat diet (HFD) feeding. In this study, at a time poi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d299e7f361025fcb5f8c430f86202b
https://doi.org/10.1074/jbc.ra120.015585
https://doi.org/10.1074/jbc.ra120.015585
Autor:
Kathryn A. Carbajal, Darby C. Peter, Austin Reuter, Haley Wienkes, Michelle E. Kimple, Rachel J. Fenske
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce730a672ff6f4c2fd56f6ae8af64f4
https://doi.org/10.1096/fasebj.2020.34.s1.03523
https://doi.org/10.1096/fasebj.2020.34.s1.03523
Autor:
Molly L. Wehner, Jeffrey M. Harrington, Michael D. Schaid, Grant M. Kelly, Rachel J. Fenske, Austin Reuter, Erin Laundre, Dudley W. Lamming, Kathryn A. Carbajal, Michelle E. Kimple, Cara L Green
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::772b903880bb9c4e0340fc904d19d741
https://doi.org/10.1096/fasebj.2020.34.s1.04098
https://doi.org/10.1096/fasebj.2020.34.s1.04098