Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kathryn, Dennehy"'
Autor:
Christopher S. Wilcox, Noritaka Kawada, Paul Modlinger, Kinjal Patel, William J. Welch, Margarida Mendonca, Kathryn Dennehy, Shakil Aslam
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H2644-H2649
Angiotensin (ANG) II activating type 1 receptors (AT1Rs) enhances superoxide anion (O2•−) and arachidonate (AA) formation. AA is metabolized by cyclooxygenases (COXs) to PGH2, which is metabolized by thromboxane (Tx)A2synthase to TxA2or oxidized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501cbd6d1c29b68ae36fa2b7f585ff61
https://doi.org/10.1152/ajpheart.00748.2007
https://doi.org/10.1152/ajpheart.00748.2007
Autor:
A.M. Leone, Kathryn Dennehy, Pritmohinder S. Gill, James Leiper, Oscar Adler, Julie Raggio, Christopher S. Wilcox, Maristela L. Onozato, Tinatin Chabrashvili, Min Li, Margarida Mendonca, Akihiro Tojo, William J. Welch, Dan Wang, Paul Modlinger, Patrick Vallance
Publikováno v:
Circulation Research. 101:627-635
Asymmetric dimethylarginine (ADMA), which inhibits NO synthase, is inactivated by N G , N G -dimethylarginine dimethylaminohydrolase (DDAH). We tested whether DDAH-1 or -2 regulates serum ADMA (S ADMA ) and/or endothelium-derived relaxing factor (EDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0de41ec5fd493226f340d2556835725
https://doi.org/10.1161/circresaha.107.158915
https://doi.org/10.1161/circresaha.107.158915
Autor:
Christopher S. Wilcox, Yifan Chen, Stephanie Connors, James Mitchell, Kinjal Patel, William J. Welch, Jonathan Blau, Margaret M. Tarpey, Margarida Mendonca, Kathryn Dennehy, Murali Krishna
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 290:R37-R43
Tempol is an amphipathic radical nitroxide (N) that acutely reduces blood pressure (BP) and heart rate (HR) in the spontaneously hypertensive rat (SHR). We investigated the hypothesis that the response to nitroxides is determined by SOD mimetic activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8811fa565a5c6fbda0ef58490598331
https://doi.org/10.1152/ajpregu.00469.2005
https://doi.org/10.1152/ajpregu.00469.2005
Autor:
Alex Karber, Margarida Mendonca, Kathryn Dennehy, Kinjal Patel, Jonathan Blau, Yuen-Sum Lao, Pedro A. Jose, Christopher S. Wilcox, William J. Welch
Publikováno v:
Kidney International. 68(1):179-187
Antihypertensive response to prolonged tempol in the spontaneously hypertensive rat.IntroductionTempol is a permeant nitroxide superoxide dismutase (SOD) mimetic that lowers mean arterial pressure (MAP) in spontaneously hypertensive rats (SHRs). We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0629455026d034f14db477a98c65f34
Autor:
Dan, Wang, Pritmohinder S, Gill, Tinatin, Chabrashvili, Maristela L, Onozato, Julie, Raggio, Margarida, Mendonca, Kathryn, Dennehy, Min, Li, Paul, Modlinger, James, Leiper, Patrick, Vallance, Oscar, Adler, Anna, Leone, Akihiro, Tojo, William J, Welch, Christopher S, Wilcox
Publikováno v:
Circulation research. 101(6)
Asymmetric dimethylarginine (ADMA), which inhibits NO synthase, is inactivated by N(G),N(G)-dimethylarginine dimethylaminohydrolase (DDAH). We tested whether DDAH-1 or -2 regulates serum ADMA (S(ADMA)) and/or endothelium-derived relaxing factor (EDRF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c82f44113dd742383c6628bfba6ff698
https://pubmed.ncbi.nlm.nih.gov/17673667
https://pubmed.ncbi.nlm.nih.gov/17673667
Autor:
Christopher S. Wilcox, Robert Langenbach, Julie T. Kawada, Nathan Ivey, Glenn Solis, Enyu Imai, Rebecca Hamel, Stephanie Connors, William J. Welch, Kathryn Dennehy, Paul Modlinger, Noritaka Kawada
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 45(6)
We used cyclooxygenase-1 (COX-1)–deficient mice to test the hypothesis that COX-1 regulates blood pressure (BP) and renal hemodynamics. The awake time (AT) mean arterial pressures (MAPs) measured by telemetry were not different between COX-1 +/+ an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b54b3b37132462cb78ff379502e0197
https://pubmed.ncbi.nlm.nih.gov/15883230
https://pubmed.ncbi.nlm.nih.gov/15883230
Autor:
William J. Welch, Toshiki Moriyama, Paul Modlinger, Shakil Aslam, Christopher S. Wilcox, Julie T. Kawada, Kathryn Dennehy, Glenn Solis, Rebecca Hamel, Enyu Imai, Noritaka Kawada
Publikováno v:
American journal of physiology. Renal physiology. 287(4)
We investigated the hypothesis that thromboxane A2(TxA2)-prostaglandin H2receptors (TP-Rs) mediate the hemodynamic responses and increase in reactive oxygen species (ROS) to ANG II (400 ng·kg−1·min−1sc for 14 days) using TP-R knockout (TP −/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedef1b9e370a75fb25dde3a98ee5626
https://pubmed.ncbi.nlm.nih.gov/15213069
https://pubmed.ncbi.nlm.nih.gov/15213069
Autor:
Noritaka, Kawada, Kathryn, Dennehy, Glenn, Solis, Paul, Modlinger, Rebecca, Hamel, T, Kawada Julie, Shakil, Aslam, Toshiki, Moriyama, Enyu, Imai, J, Welch William, S, Wilcox Christopher
Publikováno v:
American Journal of Physiology - Renal Physiology; October 2004, Vol. 287 Issue: 4 pF753-9