Výsledky vyhledávání - "Kathryn, Chaloner"

Akademický článek

GB virus C infection is associated with altered lymphocyte subset distribution and reduced T cell activation and proliferation in HIV-infected individuals.

Autor: Jack T Stapleton, Kathryn Chaloner, Jeffrey A Martenson, Jingyang Zhang, Donna Klinzman, Jinhua Xiang, Wendy Sauter, Seema N Desai, Alan Landay

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e50563 (2012)

GBV-C infection is associated with prolonged survival and with reduced T cell activation in HIV-infected subjects not receiving combination antiretroviral therapy (cART). The relationship between GBV-C and T cell activation in HIV-infected subjects w

Externí odkaz: https://doaj.org/article/4eef5ae0bfed4ade802303eac021474c

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Akademický článek

Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.

Autor: Michael A Apicella, Deborah M B Post, Andrew C Fowler, Bradley D Jones, Jed A Rasmussen, Jason R Hunt, Sayaka Imagawa, Biswa Choudhury, Thomas J Inzana, Tamara M Maier, Dara W Frank, Thomas C Zahrt, Kathryn Chaloner, Michael P Jennings, Molly K McLendon, Bradford W Gibson

Publikováno v: PLoS ONE, Vol 5, Iss 7, p e11060 (2010)

Capsular polysaccharides are important factors in bacterial pathogenesis and have been the target of a number of successful vaccines. Francisella tularensis has been considered to express a capsular antigen but none has been isolated or characterized

Externí odkaz: https://doaj.org/article/d62367cdd61d4af9906aa9878c55f4dc

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Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Publikováno v: Diabetes Care

OBJECTIVE Impaired awareness of hypoglycemia (IAH) and severe hypoglycemic events (SHEs) cause substantial morbidity and mortality in patients with type 1 diabetes (T1D). Current therapies are effective in preventing SHEs in 50–80% of patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97186d5bb1b5f2333329d31f0b4e535a
https://doi.org/10.2337/dc15-1988

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A sequential classification rule based on multiple quantitative tests in the absence of a gold standard

Autor: Jingyang Zhang, Jack T. Stapleton, Kathryn Chaloner, Ying Zhang

Publikováno v: Statistics in Medicine. 35:1359-1372

In many medical applications, combining information from multiple biomarkers could yield a better diagnosis than any single one on its own. When there is a lack of a gold standard, an algorithm of classifying subjects into the case and non-case statu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34db41e83a3b4eded8322f709b22ec17
https://doi.org/10.1002/sim.6780

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Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis

Autor: Simon C. Kao, David A. Stoltz, Amit Diwakar, Kathryn Chaloner, Andrew S. Michalski, Rebecca A. Horan, Monelle M. Tamegnon, Ryan J. Adam, Anthony J. Fischer, David K. Meyerholz, Jan L. Launspach

Publikováno v: The Laryngoscope. 125:2398-2404

Objectives/Hypothesis Tracheal cartilage ring structural abnormalities have been reported in cystic fibrosis (CF) mice and pigs. Whether similar findings are present in humans with CF is unknown. We hypothesized that tracheal cartilage ring shape and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79b8a1a152f9f16b6e547e7c1e49738
https://doi.org/10.1002/lary.25255

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Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli

Autor: John A. Wemmie, George B. Richerson, Huiyu Gong, Jacob R. Kundert, Luisa Bernardinelli, Meredith G. Parsons, Margaret P. Price, Gordon F. Buchanan, Michael J. Welsh, Leah R. Reznikov, Martin D. Cassell, Kathryn Chaloner

Publikováno v: Genes, Brain and Behavior. 13:179-194

Acid-sensing ion channels (ASICs) generate H(+) -gated Na(+) currents that contribute to neuronal function and animal behavior. Like ASIC1, ASIC2 subunits are expressed in the brain and multimerize with ASIC1 to influence acid-evoked currents and fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::402b17ec37a84af025aa02bd6c92e486
https://doi.org/10.1111/gbb.12108

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Antibody repertoire development in fetal and neonatal piglets

Autor: Peter L. Nara, Xuizhu Sun, Joseph F. Urban, Kathryn Chaloner, John E. Butler, Kelly M. Lager, Nancy Wertz, Gregory J. Tobin, David L. Francis

Publikováno v: Molecular Immunology. 49:483-494

Usage of variable region gene segments during development of the antibody repertoire in mammals is unresolved in part because of the complexity of the locus in mice and humans and the difficulty of distinguishing intrinsic from extrinsic influences i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94f8bea8255b05f933ea34438a9c54e0
https://doi.org/10.1016/j.molimm.2011.09.018

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The little brown bat, M. lucifugus, displays a highly diverse VH, DH and JH repertoire but little evidence of somatic hypermutation

Autor: Thomas H. Kunz, Sara A. Bratsch, Kathryn Chaloner, Nancy Wertz, John E. Butler

Publikováno v: Developmental & Comparative Immunology. 35:421-430

Myotis lucifugus populations in Northeastern US are being decimated by a fungal disease. Since almost nothing is known about the immune system of bats, we are characterizing the immunoglobulin genes of bats. We show that M. lucifugus has a diverse V(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bdb3e4f5bdfa263a80631a7cc1681e
https://doi.org/10.1016/j.dci.2010.06.004

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