Synthesis, crystal structure, and protonation behaviour in solution of the recently-discovered drug metabolite, N1,N10-diacetyltriethylenetetramine

Autor: Tilo Söhnel, Kathrin Wichmann, Garth J. S. Cooper

Publikováno v: Journal of Molecular Structure. 1012:37-42

N 1 ,N 10 -diacetyltriethylenetetramine (DAT) is a recently-discovered major in vivo metabolite of triethylenetetramine (TETA), a highly-selective Cu II chelator currently under clinical development as a novel first-in-class therapeutic for the cardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92b9db7785226c420efe4de9c93ef021
https://doi.org/10.1016/j.molstruc.2011.12.020

Polyamine-based anion receptors: Extraction and structural studies

Autor: Leonard F. Lindoy, Martin Schröder, Kerstin Gloe, Bianca Antonioli, Karsten Gloe, Jason R. Price, Kathrin Wichmann, Tilo Söhnel, Marco Wenzel, Alexander J. Blake

Publikováno v: Coordination Chemistry Reviews. 250:2987-3003

In the discussion that follows some of the more recent progress in the area of anion binding by synthetic polyamine receptors is presented, with emphasis given to work undertaken by the authors’ groups. A continuing theme in these studies has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::003e6ec7854c00549953c9bd07636c0b
https://doi.org/10.1016/j.ccr.2006.07.010

Metal ion recognition. Interaction of a series of successively N-benzylated derivatives of 1,4,8,11-tetraazacyclotetradecane (cyclam) with selected transition and post-transition metal ions

Autor: Sandra Farquhar, Brendan R. Rumbel, Peter Turner, Karsten Gloe, Kathrin Wichmann, Ying Dong, Leonard F. Lindoy

Publikováno v: Dalton Transactions. :1558-1566

The interaction of a series of N-benzylated cyclam ligand derivatives incorporating from one to four N-benzyl groups with cobalt(II), zinc(II), cadmium(II), lead(II) and silver(I) nitrates is reported; the results are compared with those obtained in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54247a7a721032b4872d8ed5b391786e
https://doi.org/10.1039/b300002h

Macrocyclic ligand design. Structure-function relationships involving the interaction of pyridinyl-containing, oxygen-nitrogen donor macrocycles with selected transition and post transition metal ions on progressive N-benzylation of their secondary amines

Autor: Torsten Rambusch, Leonard F. Lindoy, Brian W. Skelton, Ronald R. Fenton, Marina Fainerman-Melnikova, Peter Turner, Allan H. White, Jason R. Price, Kathrin Wichmann, Karsten Gloe

Publikováno v: Dalton transactions (Cambridge, England : 2003). (21)

Structure-function relationships underlying the interaction of progressively N-benzylated N(4)O(2)-donor macrocycles with cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II), silver(I) and lead(II) have been probed using a range of techniques t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12b41c4dd545e54d0106d4cd2bd57e4
https://pubmed.ncbi.nlm.nih.gov/15510298

Towards promising oxoanion extractants: azacages and open-chain counterparts

Autor: Kathrin Wichmann, Karsten Gloe, Gudrun Goretzki, Kerstin Gloe, David Farrell, Raewyn M. Town, Ibolya Pál, Jane Nelson, Mark Nieuwenhuyzen, Vickie McKee, Holger Stephan

Publikováno v: Dalton Discussion 5 "Ligand Design for Functional Complexes", Noordwijkerhout, The Netherlands, 10.-12.04.2003
J. Chem. Soc., Dalton Trans. (2003) 1961-1968

The efficiency of a series of amino-azacryptands for encapsulation and extraction of the oxoanions pertechnetate and perrhenate from aqueous solution is investigated and compared with that of their open-chain counterparts. The aqueous formation const

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7e91e65f86f2df19be8f09545d5892
https://www.hzdr.de/publications/Publ-5432-2