Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kathrin Würth-Roderer"'
Autor:
Helen V. Thorbjørnsrud, Luca Bressan, Tamjidmaa Khatanbaatar, Manuel Carrer, Kathrin Würth-Roderer, Gabriele Cordara, Peter Kast, Michele Cascella, Ute Krengel
Publikováno v:
Biochemistry, 62 (3)
Unlike typical chorismate mutases, the enzyme from Mycobacterium tuberculosis (MtCM) has only low activity on its own. Remarkably, its catalytic efficiency kcat/Km can be boosted more than 100-fold by complex formation with a partner enzyme. Recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f865d8c5300632314aee51594b3476e4
Autor:
Christian Stocker, Tamjidmaa Khatanbaatar, Kathrin Würth-Roderer, Gabriele Cordara, Ute Krengel, Peter Kast
Chorismate mutase (CM) and cyclohexadienyl dehydratase (CDT) catalyze two subsequent reactions in the intracellular biosynthesis of phenylalanine. Surprisingly, exported CMs and CDTs exist in bacterial pathogens. Here, we report the discovery of nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b482612f2e0397883baae69950bc1dd7
https://doi.org/10.2139/ssrn.4388939
https://doi.org/10.2139/ssrn.4388939
Autor:
Susanne Mailand, Ute Krengel, Peter Kast, Kathrin Würth-Roderer, Helen Vikdal Thorbjørnsrud, Jūrate˙ Fahrig-Kamarauskait≑
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry, 295 (51)
'Journal of Biological Chemistry ', vol: 295, pages: 17514-17534 (2020)
Journal of Biological Chemistry, 295 (51)
'Journal of Biological Chemistry ', vol: 295, pages: 17514-17534 (2020)
Chorismate mutase (CM), an essential enzyme at the branch-point of the shikimate pathway, is required for the biosynthesis of phenylalanine and tyrosine in bacteria, archaea, plants, and fungi. MtCM, the CM from Mycobacterium tuberculosis, has less t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ae18d93d1acc06ba88ace5d51e113b
http://europepmc.org/articles/PMC7762937
http://europepmc.org/articles/PMC7762937
Autor:
Kathrin Würth-Roderer, Helen Vikdal Thorbjørnsrud, Joel B. Heim, Daniel Burschowsky, Ute Krengel, Jūratė Fahrig-Kamarauskaitė, Peter Kast
Publikováno v:
Biochemistry, 57 (5)
Corynebacterium glutamicum is widely used for the industrial production of amino acids, nucleotides, and vitamins. The shikimate pathway enzymes DAHP synthase (CgDS, Cg2391) and chorismate mutase (CgCM, Cgl0853) play a key role in the biosynthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71d2eaf5e1017a0dbcc3ceb3c0de246
https://pubmed.ncbi.nlm.nih.gov/29178787
https://pubmed.ncbi.nlm.nih.gov/29178787