Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kathrin V Schmidt"'
Autor:
Wolfgang Stremmel, Kathrin V Schmidt, Vera Schuhmann, Frank Kratzer, Sven F Garbade, Claus-Dieter Langhans, Gert Fricker, Jürgen G Okun
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170742 (2017)
Elevated serum trimethylamine-N-oxide (TMAO) was previously reported to be associated with an elevated risk for cardiovascular events. TMAO originates from the microbiota-dependent breakdown of food-derived phosphatidylcholine (PC) to trimethylamine
Externí odkaz:
https://doaj.org/article/0ba801a5be684f4eb5564a30cb958479
Autor:
Jürgen G. Okun, Sean Conway, Kathrin V. Schmidt, Jonas Schumacher, Xiaoyue Wang, Roldan de Guia, Annika Zota, Johanna Klement, Oksana Seibert, Achim Peters, Adriano Maida, Stephan Herzig, Adam J. Rose
Publikováno v:
Molecular Metabolism, Vol 41, Iss , Pp 101068- (2020)
Externí odkaz:
https://doaj.org/article/a2cf1663ae7346c6918f207c081fa7c3
Autor:
Annika Zota, Roldan M. de Guia, Jonas Schumacher, Johanna Klement, Achim Peters, Xiaoyue Wang, Stephan Herzig, Adam J. Rose, Sean Conway, Oksana Seibert, Jürgen G. Okun, Kathrin V. Schmidt, Adriano Maida
Publikováno v:
Molecular Metabolism, Vol 41, Iss, Pp 101068-(2020)
Molecular Metabolism
Molecular Metabolism
Autor:
Katherine Roberts-Thomson, Ludovico Maggi, Susanne Hille, Annika Zota, Yuqin Wu, Kathrin V. Schmidt, Michelle A. Keske, Yann W. Yap, Young H Lee, Thomas Sharkie, Andrea Y. Chan, Mathias Heikenwalder, Jürgen G. Okun, Andreas Jungmann, Ryan D. Russell, Stephan Herzig, Patricia M. Rusu, Oliver J. Müller, Matthias Blüher, Adam J. Rose, Jonas Schumacher
Publikováno v:
Nature metabolism. 3(3)
Both obesity and sarcopenia are frequently associated in ageing, and together may promote the progression of related conditions such as diabetes and frailty. However, little is known about the pathophysiological mechanisms underpinning this associati
Autor:
Annika Zota, Matthias Blüher, Ludovico Maggi, Susanne Hille, Oliver J. Müller, Yann W. Yap, Adam J. Rose, Young H Lee, Stephan Herzig, Kathrin V. Schmidt, Mathias Heikenwalder, Jürgen G. Okun, Andreas Jungmann, Andrea Y. Chan, Patricia M. Rusu, Jonas Schumacher, Thomas Sharkie
Both obesity and sarcopenia are frequently associated in ageing, and together may promote the progression of related conditions such as diabetes and frailty. However, little is known about the pathophysiological mechanisms underpinning this associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492b8e07f2d20d5871f511aa3f7ea592
https://doi.org/10.1101/2020.05.25.115709
https://doi.org/10.1101/2020.05.25.115709
Autor:
Bernhard Radlwimmer, Mario Hlevnjak, Wei Wang, Kathrin V. Schmidt, M. Kirchgäßner, A. E. Lykkesfeldt, Verena Thewes, Guido Sauter, Martje Tönjes, Stefanie Heck, Ulrich Deuschle, Magdalena Schlotter, Hans-Peter Sinn, P. Windisch, Nathaniel Melling, Jürgen G. Okun, Peter Lichter, S. Kaulfuss, Andreas Schneeweiss, Yonghe Wu, Marc Zapatka, Niclas Kneisel, Reinhard Büttner, Ronald Simon, Tobias Anzeneder, H. Hess-Stumpp, Petra Schroeter
Publikováno v:
Oncogene. 36:4124-4134
Antiestrogen-resistant and triple-negative breast tumors pose a serious clinical challenge because of limited treatment options. We assessed global gene expression changes in antiestrogen-sensitive compared with antiestrogen-resistant (two tamoxifen
Autor:
Annika Zota, Oksana Seibert, Şahika Cıngır, Nicola Vallon, Tjeerd P. Sijmonsma, Jessica Fuhrmeister, Kathrin V. Schmidt, Stephan Herzig, Adriano Maida, Matthias Blüher, Adam J. Rose, Katharina Niopek, Jürgen G. Okun, Roldan M. de Guia, Mauricio Berriel Diaz
Publikováno v:
EMBO Mol. Med. 8, 654-669 (2016)
EMBO Molecular Medicine
EMBO Molecular Medicine
Recent studies have demonstrated that repeated short-term nutrient withdrawal (i.e. fasting) has pleiotropic actions to promote organismal health and longevity. Despite this, the molecular physiological mechanisms by which fasting is protective again
Autor:
Achim Peters, Jürgen G. Okun, Oksana Seibert, Roldan M. de Guia, Xiaoyue Wang, Kathrin V. Schmidt, Annika Zota, Adriano Maida, Adam J. Rose, Jonas Schumacher, Johanna Klement, Stephan Herzig, Sean Conway
Publikováno v:
Molecular Metabolism, Vol 4, Iss 10, Pp 732-740 (2015)
Molecular Metabolism
Mol. Metab. 4, 732-740 (2015)
Molecular Metabolism
Mol. Metab. 4, 732-740 (2015)
Objective One of the major side effects of glucocorticoid (GC) treatment is lean tissue wasting, indicating a prominent role in systemic amino acid metabolism. In order to uncover a novel aspect of GCs and their intracellular-receptor, the glucocorti
Autor:
Rosario M. Piro, Anders Lindroth, Rainer König, Timothy A. Chan, Daniela Karra, Irene Weibrecht, Hendrik Witt, Susan M. Hutson, Adele K. Addington, Bernhard Radlwimmer, Yoon Jung Park, Sebastian Barbus, Kathrin V. Schmidt, Jürgen G. Okun, Magdalena Schlotter, Alfa H.C. Bai, Wei Wang, Ralf Kemkemer, Volker Hovestadt, Benito Campos, Claudio Gavino Rolli, Sevin Turcan, Christel Herold-Mende, Manfred Jugold, Jörg Felsberg, Guido Reifenberger, Dieter Lemke, Peter Lichter, Stefan M. Pfister, Martje Tönjes, Sabrina Pleier, William Edmund Hull, Christoph Plass, Dominik Sturm
Publikováno v:
Nature Medicine
Here we show that glioblastoma express high levels of branched-chain amino acid transaminase 1 (BCAT1), the enzyme that initiates the catabolism of branched-chain amino acids (BCAAs). Expression of BCAT1 was exclusive to tumors carrying wild-type iso
Autor:
Gert Fricker, Kathrin V. Schmidt, Sven F. Garbade, Vera Schuhmann, Wolfgang Stremmel, Jürgen G. Okun, Claus-Dieter Langhans, Frank Kratzer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0170742 (2017)
PLoS ONE, Vol 12, Iss 1, p e0170742 (2017)
Elevated serum trimethylamine-N-oxide (TMAO) was previously reported to be associated with an elevated risk for cardiovascular events. TMAO originates from the microbiota-dependent breakdown of food-derived phosphatidylcholine (PC) to trimethylamine