Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Kathrin U Jansen"'
Autor:
Naglaa Mohamed, Yekaterina Timofeyeva, Dorota Jamrozy, Eduardo Rojas, Li Hao, Natalie C Silmon de Monerri, Julio Hawkins, Guy Singh, Bing Cai, Paul Liberator, Shite Sebastian, Robert G K Donald, Ingrid L Scully, C Hal Jones, C Buddy Creech, Isaac Thomsen, Julian Parkhill, Sharon J Peacock, Kathrin U Jansen, Matthew T G Holden, Annaliesa S Anderson
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0208356 (2019)
Staphylococcus aureus capsular polysaccharides (CP) are important virulence factors under evaluation as vaccine antigens. Clinical S. aureus isolates have the biosynthetic capability to express either CP5 or CP8 and an understanding of the relationsh
Externí odkaz:
https://doaj.org/article/67964ae0bddb44bc9baf0778c2c7d442
Autor:
Bin Jia, Lisa K McNeil, Christopher D Dupont, Konstantinos Tsioris, Rachel M Barry, Ingrid L Scully, Adebola O Ogunniyi, Christopher Gonzalez, Michael W Pride, Todd M Gierahn, Paul A Liberator, Kathrin U Jansen, J Christopher Love
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183738 (2017)
The efficacy of protein-conjugated pneumococcal polysaccharide vaccines has been well characterized for children. The level of protection conferred by unconjugated polysaccharide vaccines remains less clear, particularly for elderly individuals who h
Externí odkaz:
https://doaj.org/article/f9a232275d3844819f11312d25da5b7f
Autor:
Eduardo Rojas, Johanna Hoyos, Neil J Oldfield, Philip Lee, Mike Flint, C Hal Jones, Dlawer A A Ala'Aldeen, Kathrin U Jansen, Annaliesa S Anderson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132140 (2015)
The reservoir for Neisseria meningitidis (Nm) is the human oropharynx. Implementation of Nm serogroup C (NmC) glycoconjugate vaccines directly reduced NmC carriage. Prophylactic vaccines are now available to prevent disease caused by the five major N
Externí odkaz:
https://doaj.org/article/36a9d7ded5454c5bac50ee98e296e884
Autor:
Wouter Rozemeijer, Pamela Fink, Eduardo Rojas, C Hal Jones, Danka Pavliakova, Peter Giardina, Ellen Murphy, Paul Liberator, Qin Jiang, Douglas Girgenti, Remco P H Peters, Paul H M Savelkoul, Kathrin U Jansen, Annaliesa S Anderson, Jan Kluytmans
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116945 (2015)
Staphylococcus aureus is a versatile pathogen of medical significance, using multiple virulence factors to cause disease. A prophylactic S. aureus 4-antigen (SA4Ag) vaccine comprising capsular polysaccharide (types 5 and 8) conjugates, clumping facto
Externí odkaz:
https://doaj.org/article/b3d3ac54d8554b799777fbb5dee5bac9
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
A key aspect of the pathogenesis of the Gram positive bacterium Staphylococcus aureus is its ability to rapidly adapt to the host environment during the course of an infection. To successfully establish infection, the organism deploys a variety of su
Externí odkaz:
https://doaj.org/article/6cafeaa4fb6a470d856e6490015db056
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77874 (2013)
Staphylococcus aureus is a successful human pathogen that has developed several approaches to evade the immune system, including resistance strategies to prevent oxidative killing by immune cells. One mechanism by which this evasion occurs is by prod
Externí odkaz:
https://doaj.org/article/572d78d3434a4dd195238bdfef613cb6
Autor:
Michael W. Simon, Regine Bataille, Nicole S. Caldwell, Bradford D. Gessner, Luis Jodar, Erik Lamberth, Yahong Peng, Daniel A. Scott, Lanyu Lei, Peter C. Giardina, William C. Gruber, Kathrin U. Jansen, Allison Thompson, Wendy Watson
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 2 (2023)
ABSTRACTUse of pneumococcal conjugate vaccines (PCVs) has led to substantial reductions in the global burden of pediatric pneumococcal disease. Expansion of serotype coverage has been achieved by increasing PCV valency, but this may carry the potenti
Externí odkaz:
https://doaj.org/article/eee4a903246c45198a86e37958cb0a5c
Autor:
Chaitanya Kurhade, Jing Zou, Hongjie Xia, Mingru Liu, Qi Yang, Mark Cutler, David Cooper, Alexander Muik, Ugur Sahin, Kathrin U. Jansen, Ping Ren, Xuping Xie, Kena A. Swanson, Pei-Yong Shi
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1828-1832 (2022)
Distinct SARS-CoV-2 Omicron sublineages have evolved showing increased fitness and immune evasion than the original Omicron variant BA.1. Here, we report the neutralization activity of sera from BNT162b2 vaccinated individuals or unimmunized Omicron
Externí odkaz:
https://doaj.org/article/daff56ad156a43d398c1caae173a8eba
Autor:
Chaitanya Kurhade, Jing Zou, Hongjie Xia, Hui Cai, Qi Yang, Mark Cutler, David Cooper, Alexander Muik, Kathrin U. Jansen, Xuping Xie, Kena A. Swanson, Pei‑Yong Shi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
It is essential to test the neutralization of approved vaccines against SARSCoV-2 Omicron sublineages. Kurhade et al. find that sera from people with three doses of BNT162b2 neutralize Omicron BA.1, BA.2, and BA.3 to a lesser extent than the original
Externí odkaz:
https://doaj.org/article/d14e142b43154ca1aba34a62462d7ea2
Autor:
Charu Sabharwal, Vani Sundaraiyer, Yahong Peng, Lisa Moyer, Todd J. Belanger, Bradford D. Gessner, Luis Jodar, Kathrin U. Jansen, William C. Gruber, Daniel A. Scott, Wendy Watson
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 6 (2022)
The aim of this post hoc analysis was to describe the immunogenicity of the 20-valent pneumococcal conjugate vaccine (PCV20) in adults with chronic medical conditions or smoking that place them at increased risk of developing pneumococcal disease. Da
Externí odkaz:
https://doaj.org/article/c1b7ed93b86145a38cb32c74e643741f