Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kathrin Schunck"'
Autor:
Judith Dönig, Hannah Mende, Jimena Davila Gallesio, Kristina Wagner, Paul Hotz, Kathrin Schunck, Tanja Piller, Soraya Hölper, Sara Uhan, Manuel Kaulich, Matthias Wirth, Ulrich Keller, Georg Tascher, Katherine E. Bohnsack, Stefan Müller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Ribosome biogenesis is a multi-step process, in which a network of trans-acting factors ensures the coordinated assembly of pre-ribosomal particles in order to generate functional ribosomes. Ribosome biogenesis is tightly coordinated with ce
Externí odkaz:
https://doaj.org/article/2edd2d3bfab1439685a793e49a34886e
Autor:
Markus Schick, Le Zhang, Sabine Maurer, Hans Carlo Maurer, Konstandina Isaakaidis, Lara Schneider, Upayan Patra, Kathrin Schunck, Elena Rohleder, Julia Hofstetter, Apoorva Baluapuri, Anna Katharina Scherger, Julia Slotta-Huspenina, Franziska Hettler, Julia Weber, Thomas Engleitner, Roman Maresch, Jolanta Slawska, Richard Lewis, Rouzanna Istvanffy, Stefan Habringer, Katja Steiger, Armin Baiker, Robert A. J. Oostendorp, Cornelius Miething, Hans-Peter Lenhof, Florian Bassermann, Björn Chapuy, Matthias Wirth, Elmar Wolf, Roland Rad, Stefan Müller, Ulrich Keller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
SUMOylation is a post-translational modification that has been shown to be altered in cancer. Here, the authors show that loss of the SUMO isopeptidase SENP6 leads to unrestricted SUMOylation and genomic instability promoting lymphomagenesis and gene
Externí odkaz:
https://doaj.org/article/ba5bc46837534430996429dd0c309256
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
The dynamic and reversible post-translational modification of proteins and protein complexes with the ubiquitin-related SUMO modifier regulates a wide variety of nuclear functions, such as transcription, replication and DNA repair. SUMO can be attach
Externí odkaz:
https://doaj.org/article/4a7a2b8da90c45c8b5912f81b5aac158
Autor:
Alexander Muckenhuber, Anna Katharina Scherger, Steve Langston, Günter Schneider, Zonera Hassan, Katja Steiger, Alexander Biederstädt, Markus Schick, Stefan Müller, Zahra Dantes, Christian Schneeweis, Andrea Coluccio, Maximilian Reichert, Felix Orben, Lara Schneider, Dieter Saur, Jolanta Slawska, Hans-Peter Lenhof, Matthias Wirth, Roland Rad, Kathrin Schunck, Gerrit Siegers, Wilko Weichert, Ulrich Keller, Yingfen Hong, Lisa M. Nilsson, Jonas Nilsson
Publikováno v:
Gut
ObjectivePancreatic ductal adenocarcinoma (PDAC) still carries a dismal prognosis with an overall 5-year survival rate of 9%. Conventional combination chemotherapies are a clear advance in the treatment of PDAC; however, subtypes of the disease exist