Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathrin Roderer"'
Autor:
Kathrin Roderer, Martin Neuenschwander, Giosiana Codoni, Severin Sasso, Marianne Gamper, Peter Kast
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116234 (2014)
The shikimate pathway enzyme chorismate mutase converts chorismate into prephenate, a precursor of Tyr and Phe. The intracellular chorismate mutase (MtCM) of Mycobacterium tuberculosis is poorly active on its own, but becomes >100-fold more efficient
Externí odkaz:
https://doaj.org/article/e9c2f6fb77be47b290ba366282779510
Autor:
Kathrin Roderer, Peter Kast
Publikováno v:
CHIMIA, Vol 63, Iss 6 (2009)
Directed evolution strategies are being applied ever more frequently to develop novel and improved enzymes for many applications, including those contributing to 'white biotechnology'. In addition to engineering new biocatalysts, evolutionary strateg
Externí odkaz:
https://doaj.org/article/9b02c41b958b48f78406e1a113f37d77
Autor:
Steffi Munack, Jurate Kamarauskaite, Peter Kast, Ute Krengel, Severin Sasso, Kathrin Roderer, Mats Ökvist, André van Eerde
Publikováno v:
J. Mol. Biol.
DAHP synthase and chorismate mutase catalyze key steps in the shikimate biosynthetic pathway en route to aromatic amino acids. In Mycobacterium tuberculosis, chorismate mutase (MtCM; Rv0948c), located at the branch point toward phenylalanine and tyro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f51e6e62f2177d485fa3d821e7efc3f
Autor:
Giosiana Codoni, Peter Kast, Kathrin Roderer, Severin Sasso, Mats Ökvist, Ute Krengel, Marianne Gamper
Publikováno v:
The EMBO Journal. 28:2128-2142
Chorismate mutase catalyzes a key step in the shikimate biosynthetic pathway towards phenylalanine and tyrosine. Curiously, the intracellular chorismate mutase of Mycobacterium tuberculosis (MtCM; Rv0948c) has poor activity and lacks prominent active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e2716327febc981225c5fff7e3abbf
https://doi.org/10.1038/emboj.2009.165
https://doi.org/10.1038/emboj.2009.165
Autor:
Ute Krengel, Lise-Lotte Gundersen, Mats Ökvist, Steffi Munack, André van Eerde, Peter Kast, Vincent Leroux, Kathrin Roderer
Publikováno v:
Chemistrybiodiversity. 9(11)
Tuberculosis (TB) is a devastating disease that claims millions of lives every year. Hindered access or non-compliance to medication, especially in developing countries, led to drug resistance, further aggravating the situation. With current standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad745110a2d30b380838edce766154d5
https://pubmed.ncbi.nlm.nih.gov/23161632
https://pubmed.ncbi.nlm.nih.gov/23161632
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 68:s27-s27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d074297d0195c9ab70951a5d8c2db276
https://doi.org/10.1107/s0108767312099485
https://doi.org/10.1107/s0108767312099485
Autor:
Peter Kast, Kathrin Roderer
Publikováno v:
CHIMIA, Vol 63, Iss 6 (2009)
Directed evolution strategies are being applied ever more frequently to develop novel and improved enzymes for many applications, including those contributing to 'white biotechnology'. In addition to engineering new biocatalysts, evolutionary strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec1b5100343d0f902ef34dff6d536a
https://doi.org/10.2533/chimia.2009.313
https://doi.org/10.2533/chimia.2009.313