Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Kathrin Kalies"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Epidermolysis bullosa acquisita (EBA) is a muco-cutaneous autoimmune disease characterized and caused by autoantibodies targeting type VII collagen (COL7). The treatment of EBA is notoriously difficult, with a median time to remission of 9 months. In
Externí odkaz:
https://doaj.org/article/41846c02a8354d299b2bbcda8da55834
Autor:
Saeedeh Ghorbanalipoor, Shirin Emtenani, Melissa Parker, Mayumi Kamaguchi, Colin Osterloh, Manuela Pigors, Natalie Gross, Stanislav Khil’chenko, Anika Kasprick, Sabrina Patzelt, Diana Wortmann, Ibrahim O. Ibrahim, Kentaro Izumi, Stephanie Goletz, Katharina Boch, Kathrin Kalies, Katja Bieber, Paul Smith, Enno Schmidt, Ralf J. Ludwig
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/cfbf68eeedc54b9a85c2edcd756776b3
Autor:
Markus Niebuhr, Farbod Bahreini, Anke Fähnrich, Christina Bomholt, Katja Bieber, Enno Schmidt, Saleh Ibrahim, Christoph M. Hammers, Kathrin Kalies
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autoimmune diseases develop over years - starting from a subclinical phenotype to clinically manifest autoimmune disease. The factors that drive this transition are ill-defined. To predict the turning point towards clinical disease and to intervene i
Externí odkaz:
https://doaj.org/article/fb7fbde9e3184d9bba14938530d02777
Autor:
Saeedeh Ghorbanalipoor, Shirin Emtenani, Melissa Parker, Mayumi Kamaguchi, Colin Osterloh, Manuela Pigors, Natalie Gross, Stanislav Khil’chenko, Anika Kasprick, Sabrina Patzelt, Diana Wortmann, Ibrahim O. Ibrahim, Kentaro Izumi, Stephanie Goletz, Katharina Boch, Kathrin Kalies, Katja Bieber, Paul Smith, Enno Schmidt, Ralf J. Ludwig
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic blistering at the skin and/or mucous membranes, accompanied by a varying degree of inflammation, is the clinical hallmark of pemphigoid diseases that impose a major medical burden. Pemphigoid diseases are caused by autoantibodies targeting st
Externí odkaz:
https://doaj.org/article/c4fc3f38cd5048a4b93212cdf1cf1518
Publikováno v:
Bio-Protocol, Vol 12, Iss 11 (2022)
During adaptive immune responses, germinal centers (GC) appear as transient microstructures, in which antigen-specific B and T cells interact with each other. Because only the antigen-activated B and T cells, such as Plasmablasts or follicular T help
Externí odkaz:
https://doaj.org/article/ae1643bc089b40b08b825dfcec52f80a
Autor:
Farbod Bahreini, Markus Niebuhr, Julia Belde, Katja Bieber, Juergen Westermann, Kathrin Kalies
Publikováno v:
Bio-Protocol, Vol 12, Iss 10 (2022)
Autoreactive T cells in autoantibody-mediated autoimmune diseases can be divided into two major subsets: (i) follicular T helper cells (Tfh) that provide T cell help in germinal centers (GC) and (ii) effector T (Teff) cells that immigrate into periph
Externí odkaz:
https://doaj.org/article/62c02e28810f430d9f773928dfaa7628
Autor:
Cornelia Tune, Julia Hahn, Stella E. Autenrieth, Martin Meinhardt, Rene Pagel, Andrea Schampel, Lisa-Kristin Schierloh, Kathrin Kalies, Juergen Westermann
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 16, Iss , Pp 100312- (2021)
It is well known that sleep promotes immune functions. In line with this, a variety of studies in animal models and humans have shown that sleep restriction following an antigen challenge dampens the immune response on several levels which leads to e
Externí odkaz:
https://doaj.org/article/7eb12f02553b48fe83269b5d29f85e4a
Autor:
Markus Niebuhr, Julia Belde, Anke Fähnrich, Arnauld Serge, Magali Irla, Christoph T Ellebrecht, Christoph M Hammers, Katja Bieber, Jürgen Westermann, Kathrin Kalies
Publikováno v:
eLife, Vol 10 (2021)
Follicular T helper cells (Tfh) are a specialized subset of CD4 effector T cells that are crucial for germinal center (GC) reactions and for selecting B cells to undergo affinity maturation. Despite this central role for humoral immunity, only few da
Externí odkaz:
https://doaj.org/article/5c629f812223404cac261caf6eb8a22c
Autor:
Cornelia Tune, Martin Meinhardt, Kathrin Kalies, Rene Pagel, Lisa-Kristin Schierloh, Julia Hahn, Stella E. Autenrieth, Christiane E. Koch, Henrik Oster, Andrea Schampel, Juergen Westermann
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 5, Iss , Pp 100082- (2020)
Sleep is known to improve immune function ranging from cell distribution in the naïve state to elevated antibody titers after an immune challenge. The underlying mechanisms still remain unclear, partially because most studies have focused on the ana
Externí odkaz:
https://doaj.org/article/f0359f7f9fce4e0da613a5a5c99f47dd
Autor:
Helge Müller-Fielitz, Marcus Stahr, Mareike Bernau, Marius Richter, Sebastian Abele, Victor Krajka, Anika Benzin, Jan Wenzel, Kathrin Kalies, Jens Mittag, Heike Heuer, Stefan Offermanns, Markus Schwaninger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The hypothalamic-pituitary-thyroid (HPT) axis regulates a wide range of physiological processes. Here the authors show that hypothalamic tanycytes play a role in the homeostatic regulation of the HPT axis; activation of TRH signaling in tanycytes ele
Externí odkaz:
https://doaj.org/article/c5cc71a5e3d64ec38fd693c1f9663f55