Fever of unknown origin in renal transplant patients with tacrolimus

Autor: Alexander R. Rosenkranz, Michael A. Rudnicki, Gert Mayer, Martin Auinger, Kathrin Hochegger, Walter Mark, Raimund Margreiter

Publikováno v: Clinical Transplantation. 23:575-579

The immunosuppressive agent tacrolimus is now widely used for the prevention of acute and chronic rejection in renal allograft recipients. We here report on three patients, who developed drug-induced fever due to tacrolimus one to five months after r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827dc1d01ab2f94dc4435bdba3545179
https://doi.org/10.1111/j.1399-0012.2008.00941.x

Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression

Autor: Nico van Rooijen, Milan Theurl, Guenter Weiss, Kathrin Hochegger, Klaus Schuemann, V. Nathan Subramaniam, Peter Obrist, Igor Theurl

Publikováno v: Journal of Molecular Medicine, 86(7), 825-835. Springer Verlag
Theurl, M, Theurl, I, Hochegger, K, Obrist, P, Subramaniam, N, van Rooijen, N, Schuemann, K & Weiss, G 2008, ' Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression ', Journal of Molecular Medicine, vol. 86, no. 7, pp. 825-835 . https://doi.org/10.1007/s00109-008-0346-y

Hepcidin, a small cationic liver derived peptide, is a master regulator of body iron homeostasis. Cytokines and iron availability have so far been identified as regulators of hepcidin expression. Herein, we investigated the functional role of Kupffer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf837f5a6f687fe81b726f17a0c6e69
https://doi.org/10.1007/s00109-008-0346-y

Impact of ENPP1 genotype on arterial calcification in patients with end-stage renal failure

Autor: Emanuel Zitt, Alexander R. Rosenkranz, Gudrun Feuchtner, Ivan Tancevski, Gert Mayer, Andreas Ritsch, Florian Kronenberg, Philipp Eller, Kathrin Hochegger, Josef R. Patsch

Publikováno v: Nephrology Dialysis Transplantation. 23:321-327

Background. Ectonucleotide pyrophosphatase/ phosphodiesterase-1 (ENPP1) generates inorganic pyrophosphate, a solute that serves as an essential physiological inhibitor of calcification. Inactivating mutations of ENPP1 are associated with generalized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5137cceeae1756641b9083e2d5a157c8
https://doi.org/10.1093/ndt/gfm566

p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury

Autor: Andrea Tagwerker, Kathrin Hochegger, Dorothea Heininger, Alexander R. Rosenkranz, Gert Mayer, Julia M. Huber, Christian Koppelstaetter

Publikováno v: American Journal of Physiology-Renal Physiology. 292:F762-F768

In many clinical settings, the duration of renal ischemia and therefore the outcome of acute renal failure cannot be determined adequately. Renal ischemia reperfusion injury is known to shorten telomeres and upregulate stress-induced genes, such as t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f574fb60f6f01f7e98be67c18d5c65
https://doi.org/10.1152/ajprenal.00084.2006

CD4+CD25+ Regulatory T Cells Inhibit Experimental Anti-Glomerular Basement Membrane Glomerulonephritis in Mice

Autor: Holger Rumpold, Eberhard Gunsilius, Kathrin Hochegger, Anna Maria Wolf, Guenther Gastl, Alexander R. Rosenkranz, Dominik Wolf, Gert Mayer, Herbert Tilg

Publikováno v: Journal of the American Society of Nephrology. 16:1360-1370

CD4 + CD25 + regulatory T cells (Treg) are of critical importance for the maintenance of tolerance. The kidney is frequently involved in autoimmune diseases, such as lupus erythematosus or glomerulonephritis (GN). Therefore, the therapeutic efficacy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc86beb3220dc8cdc87e1eed9835815c
https://doi.org/10.1681/asn.2004100837