Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Kathrin Herrmann"'
Autor:
Catharine E. Krebs, Kathrin Herrmann
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Laws and policies are in place around the world to promote the replacement and reduction of nonhuman animals in science. These principles are rooted not just in ethical considerations for animals, but also in scientific considerations regarding the l
Externí odkaz:
https://doaj.org/article/ddcaf7d5ab0145598e42e2b0ed2be34f
Autor:
Itzy E. Morales Pantoja, Lena Smirnova, Alysson R. Muotri, Karl J. Wahlin, Jeffrey Kahn, J. Lomax Boyd, David H. Gracias, Timothy D. Harris, Tzahi Cohen-Karni, Brian S. Caffo, Alexander S. Szalay, Fang Han, Donald J. Zack, Ralph Etienne-Cummings, Akwasi Akwaboah, July Carolina Romero, Dowlette-Mary Alam El Din, Jesse D. Plotkin, Barton L. Paulhamus, Erik C. Johnson, Frederic Gilbert, J. Lowry Curley, Ben Cappiello, Jens C. Schwamborn, Eric J. Hill, Paul Roach, Daniel Tornero, Caroline Krall, Rheinallt Parri, Fenna Sillé, Andre Levchenko, Rabih E. Jabbour, Brett J. Kagan, Cynthia A. Berlinicke, Qi Huang, Alexandra Maertens, Kathrin Herrmann, Katya Tsaioun, Raha Dastgheyb, Christa Whelan Habela, Joshua T. Vogelstein, Thomas Hartung
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of powe
Externí odkaz:
https://doaj.org/article/aebc0f0cd878418ebed9205a612b1932
Autor:
Elisabeth H. Ormandy, Daniel M. Weary, Katarina Cvek, Mark Fisher, Kathrin Herrmann, Pru Hobson-West, Michael McDonald, William Milsom, Margaret Rose, Andrew Rowan, Joanne Zurlo, Marina A.G. von Keyserlingk
Publikováno v:
Animals, Vol 9, Iss 9, p 622 (2019)
In November 2013, a group of international experts in animal research policy (n = 11) gathered in Vancouver, Canada, to discuss openness and accountability in animal research. The primary objective was to bring together participants from various juri
Externí odkaz:
https://doaj.org/article/d6a0b1e272174cd0b5fb0507353cf77f
Autor:
Gail F Davies, Beth J Greenhough, Pru Hobson-West, Robert G W Kirk, Ken Applebee, Laura C Bellingan, Manuel Berdoy, Henry Buller, Helen J Cassaday, Keith Davies, Daniela Diefenbacher, Tone Druglitrø, Maria Paula Escobar, Carrie Friese, Kathrin Herrmann, Amy Hinterberger, Wendy J Jarrett, Kimberley Jayne, Adam M Johnson, Elizabeth R Johnson, Timm Konold, Matthew C Leach, Sabina Leonelli, David I Lewis, Elliot J Lilley, Emma R Longridge, Carmen M McLeod, Mara Miele, Nicole C Nelson, Elisabeth H Ormandy, Helen Pallett, Lonneke Poort, Pandora Pound, Edmund Ramsden, Emma Roe, Helen Scalway, Astrid Schrader, Chris J Scotton, Cheryl L Scudamore, Jane A Smith, Lucy Whitfield, Sarah Wolfensohn
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158791 (2016)
Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving la
Externí odkaz:
https://doaj.org/article/5d4d2534dba34d3ea79fb6452d4540cb
Publikováno v:
Alternatives to Laboratory Animals. 51:102-135
The failure rate for the translation of drugs from animal testing to human treatments remains at over 92%, where it has been for the past few decades. The majority of these failures are due to unexpected toxicity — that is, safety issues revealed i
Autor:
Thomas Hartung, Lena Smirnova, Itzy E. Morales Pantoja, Akwasi Akwaboah, Dowlette-Mary Alam El Din, Cynthia A. Berlinicke, J. Lomax Boyd, Brian S. Caffo, Ben Cappiello, Tzahi Cohen-Karni, J. Lowry Curley, Ralph Etienne-Cummings, Raha Dastgheyb, David H. Gracias, Frederic Gilbert, Christa Whelan Habela, Fang Han, Timothy D. Harris, Kathrin Herrmann, Eric J. Hill, Qi Huang, Rabih E. Jabbour, Erik C. Johnson, Brett J. Kagan, Caroline Krall, Andre Levchenko, Paul Locke, Alexandra Maertens, Monica Metea, Alysson R. Muotri, Rheinallt Parri, Barton L. Paulhamus, Jesse D. Plotkin, Paul Roach, July Carolina Romero, Jens C. Schwamborn, Fenna Sillé, Alexander S. Szalay, Katya Tsaioun, Daniel Tornero, Joshua T. Vogelstein, Karl J. Wahlin, Donald J. Zack
Publikováno v:
Frontiers in Science. 1
We, the participants of the First Organoid Intelligence Workshop - "Forming an OI Community" (22-24 February 2022), call on the international scientific community to explore the potential of human brain-based organoid cell cultures to advance our und
Publikováno v:
ALTEX. :158-162
Autor:
Dirk Grimm, Josefine Sippel, Quang H Pham, Marinee Chuah, Martin Lenter, Christopher Borowski, Susanne Hille, Oliver J. Müller, Norbert Frey, Jihad El Andari, Jonas Weinmann, Warut Tulalamba, Anca Remes, Thorsten Lamla, Sabrina Weis, Anne-Kathrin Herrmann, Thierry VandenDriessche, Tanja Schönberger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Adeno-associated virus (AAV) forms the basis for several commercial gene therapy products and for countless gene transfer vectors derived from natural or synthetic viral isolates that are under intense preclinical evaluation. Here, we report a versat
Autor:
Manuela, Cassotta, Hugo, Geerts, Lise, Harbom, Tiago F, Outeiro, Iosif, Pediaditakis, Orly, Reiner, Stefan, Schildknecht, Jens C, Schwamborn, Jarrod, Bailey, Kathrin, Herrmann, Helena T, Hogberg
Publikováno v:
ALTEX.
Parkinson’s disease (PD) is a complex neurodegenerative condition with a multifactorial origin. To date, approaches to drug discovery for PD have resulted in symptomatic therapies for the motor manifestations and signs associated with neurodegenera