Novel protein biomarkers for pneumonia and acute exacerbations in COPD: a pilot study

Autor: Anna Lena Jung, Maria Han, Kathrin Griss, Wilhelm Bertrams, Christoph Nell, Timm Greulich, Andreas Klemmer, Hendrik Pott, Dominik Heider, Claus F. Vogelmeier, Stefan Hippenstiel, Norbert Suttorp, Bernd Schmeck

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

IntroductionCommunity-acquired pneumonia (CAP) and acute exacerbations of chronic obstructive pulmonary disease (AECOPD) result in high morbidity, mortality, and socio-economic burden. The usage of easily accessible biomarkers informing on disease en

Externí odkaz: https://doaj.org/article/19100ed459f44882b71674f7d9a3346d

Transcriptional analysis identifies potential biomarkers and molecular regulators in acute malaria infection

Autor: Bernd Schmeck, M Han, Stefan Hippenstiel, Claus Vogelmeier, Kathrin Griss, Kerstin Seidel, Wilhelm Bertrams, Jochen Wilhelm, Florian Finkernagel, Norbert Suttorp

Publikováno v: Life sciences. 270

Aims Malaria is a serious health threat in tropical countries. The causative parasite of Malaria tropica, the severe form, is the protozoan Plasmodium falciparum. In humans, it infects red blood cells, compromising blood flow and tissue perfusion. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d37040b6244b41bd1a01044dbfa94ae
https://pubmed.ncbi.nlm.nih.gov/33545200

Transcriptional Analysis identifies long non-coding RNAs as potential biomarkers in pneumonia and COPD exacerbation

Autor: Kerstin Seidel, Kathrin Griss, Claus Vogelmeier, J Vera-Gonzalez, Florian Finkernagel, Bernd Schmeck, Alexandra Sittka-Stark, M Han, Norbert Suttorp, Stefan Hippenstiel, Andreas Klemmer, Timm Greulich, Wilhelm Bertrams, Jochen Wilhelm

Publikováno v: 61. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V..

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7077fc2df4f544822c2fcd2da229a62
https://doi.org/10.1055/s-0039-3403105

Surface Proteome of Plasma Extracellular Vesicles as Biomarkers for Pneumonia and Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Autor: Rikke Bæk, Malene Jørgensen, Rembert Koczulla, Kristina Auf Dem Brinke, Wilhelm Bertrams, Stefan Hippenstiel, Nina Timmesfeld, Timm Greulich, Norbert Suttorp, Anna Lena Jung, M Han, Bernd Schmeck, Kathrin Griss

Publikováno v: Jung, A L, Møller Jørgensen, M, Bæk, R, Griss, K, Han, M, Auf Dem Brinke, K, Timmesfeld, N, Bertrams, W, Greulich, T, Koczulla, R, Hippenstiel, S, Suttorp, N & Schmeck, B 2020, ' Surface proteome of plasma extracellular vesicles as biomarkers for pneumonia and acute exacerbation of chronic obstructive pulmonary disease ', The Journal of Infectious Diseases, vol. 221, no. 2, pp. 325-335 . https://doi.org/10.1093/infdis/jiz460

Background Community-acquired pneumonia (CAP) and acute exacerbation of chronic obstructive pulmonary disease (AECOPD) represent a major burden of disease and death and their differential diagnosis is critical. A potential source of relevant accessib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbb8bc8dc087e198461c945c50c38f8
https://pubmed.ncbi.nlm.nih.gov/31617573

An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data

Autor: Wilhelm Bertrams, Martina Cantone, Martin Eberhardt, Pia Wentker, Julio Vera, Bernd Schmeck, Kathrin Griss, Florian S. Dreyer

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 198(5)

Macrophages (Mϕs) are key players in the coordination of the lifesaving or detrimental immune response against infections. The mechanistic understanding of the functional modulation of Mϕs by pathogens and pharmaceutical interventions at the signal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1734b5c5941bbd59f6a66039e546ed23
https://pubmed.ncbi.nlm.nih.gov/28137890