Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kathrin Gottlob"'
Autor:
Eugene S. Kandel, Maura O'Leary, Suzanne D. Conzen, Nissim Hay, Pratibha Khanduri, Kathrin Gottlob, Andrew J. Wagner
Publikováno v:
Molecular and Cellular Biology. 20:6008-6018
Analysis of amino-terminus mutants of c-Myc has allowed a systematic study of the interrelationship between Myc's ability to regulate transcription and its apoptotic, proliferative, and transforming functions. First, we have found that c-Myc-accelera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7319a674f0829c5197cce8a9a2dee20
https://doi.org/10.1128/mcb.20.16.6008-6018.2000
https://doi.org/10.1128/mcb.20.16.6008-6018.2000
Autor:
Irina Klaman, Peter J. Wild, Glen Kristiansen, Elke Ebner, Edgar Dahl, Christian Pilarsky, André Rosenthal, Klaus Hermann, Ruth Knuechel, Bernd Hinzmann, Arndt Hartmann, Matthias Dürst, Monika Klinkhammer-Schalke, Kathrin Gottlob, Hagen Blaszyk
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(13)
Purpose: The aim of the present study was to identify human genes that might prove useful in the diagnosis and therapy of primary breast cancer. Experimental Design: Twenty-four matched pairs of invasive ductal breast cancer and corresponding benign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4167d8c7f6aac73365e3ad96c88ba06
https://pubmed.ncbi.nlm.nih.gov/16818692
https://pubmed.ncbi.nlm.nih.gov/16818692
Autor:
Kathrin Gottlob, R. Brooks Robey, Jennifer E. Skeen, Nathan Majewski, Veronique Nogueira, Navdeep S. Chandel, Platina E. Coy, Prashanth T. Bhaskar, Craig B. Thompson, Nissim Hay
Publikováno v:
Molecular cell. 16(5)
The serine/threonine kinase Akt inhibits mitochondrial cytochrome c release and apoptosis induced by a variety of proapoptotic stimuli. The antiapoptotic activity of Akt is coupled, at least in part, to its effects on cellular metabolism. Here, we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83224bb1284c52215012bd1df4b3defa
https://pubmed.ncbi.nlm.nih.gov/15574336
https://pubmed.ncbi.nlm.nih.gov/15574336
Publikováno v:
The Journal of biological chemistry. 277(13)
Glucose (Glc) metabolism protects cells against oxidant injury. By virtue of their central position in both Glc uptake and utilization, hexokinases (HKs) are ideally suited to contribute to these effects. Compatible with this hypothesis, endogenous H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2398e99bd2681cf2308af8dfdcc9d377
https://pubmed.ncbi.nlm.nih.gov/11751868
https://pubmed.ncbi.nlm.nih.gov/11751868
Autor:
Wei Weng, Tanya Shiyanova, William S. Chen, Mei Ling Chen, Ryo Suzuki, Pei Zhang Xu, Kathrin Gottlob, Karen Sokol, Igor B. Roninson, Nissim Hay, Takashi Kadowaki, Kazuyuki Tobe
The serine/threonine kinase Akt has been implicated in the control of cell survival and metabolism. Here we report the disruption of the most ubiquitously expressed member of theakt family of genes, akt1, in the mouse. Akt1−/− mice are viable but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd737df382b1d13eca0d11b3b95547e4
https://europepmc.org/articles/PMC312770/
https://europepmc.org/articles/PMC312770/
Autor:
Kathrin Gottlob, Nathan Majewski, Scott Kennedy, Nissim Hay, R. Brooks Robey, Eugene S. Kandel
Publikováno v:
Genesdevelopment. 15(11)
The serine/threonine kinase Akt/PKB is a major downstream effector of growth factor–mediated cell survival. Activated Akt, like Bcl-2 and Bcl-xL, prevents closure of a PT pore component, the voltage-dependent anion channel (VDAC); intracellular aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3a318af108d1318fa833a944a53eb7
https://pubmed.ncbi.nlm.nih.gov/11390360
https://pubmed.ncbi.nlm.nih.gov/11390360