Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kathrin Gianmoena"'
Autor:
Ranjan Kumar Maji, Beate Czepukojc, Michael Scherer, Sascha Tierling, Cristina Cadenas, Kathrin Gianmoena, Nina Gasparoni, Karl Nordström, Gilles Gasparoni, Stephan Laggai, Xinyi Yang, Anupam Sinha, Peter Ebert, Maren Falk-Paulsen, Sarah Kinkley, Jessica Hoppstädter, Ho-Ryun Chung, Philip Rosenstiel, Jan G. Hengstler, Jörn Walter, Marcel H. Schulz, Sonja M. Kessler, Alexandra K. Kiemer
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Fatty liver disease or the accumulation of fat in the liver, has been reported to affect the global population. This comes with an increased risk for the development of fibrosis, cirrhosis, and hepatocellular carcinoma. Yet, little is known
Externí odkaz:
https://doaj.org/article/08abcdc296d74786a777114970ddef43
Autor:
Kathrin Gianmoena, Nina Gasparoni, Adelina Jashari, Philipp Gabrys, Katharina Grgas, Ahmed Ghallab, Karl Nordström, Gilles Gasparoni, Jörg Reinders, Karolina Edlund, Patricio Godoy, Alexander Schriewer, Heiko Hayen, Christian A. Hudert, Georg Damm, Daniel Seehofer, Thomas S. Weiss, Peter Boor, Hans-Joachim Anders, Manga Motrapu, Peter Jansen, Tobias S. Schiergens, Maren Falk-Paulsen, Philip Rosenstiel, Clivia Lisowski, Eduardo Salido, Rosemarie Marchan, Jörn Walter, Jan G. Hengstler, Cristina Cadenas
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109526- (2021)
Summary: Epigenetic modifications (e.g. DNA methylation) in NAFLD and their contribution to disease progression and extrahepatic complications are poorly explored. Here, we use an integrated epigenome and transcriptome analysis of mouse NAFLD hepatoc
Externí odkaz:
https://doaj.org/article/8d9cdcdc3d35492a92af90d5a6d5d7cb
Autor:
Sonja M. Kessler, Yvette Simon, Katja Gemperlein, Kathrin Gianmoena, Cristina Cadenas, Vincent Zimmer, Juliane Pokorny, Ahmad Barghash, Volkhard Helms, Nico van Rooijen, Rainer M. Bohle, Frank Lammert, Jan G. Hengstler, Rolf Mueller, Johannes Haybaeck, Alexandra K. Kiemer
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 5762-5773 (2014)
Non-alcoholic steatohepatitis (NASH) represents a risk factor for the development of hepatocellular carcinoma (HCC) and is characterized by quantitative and qualitative changes in hepatic lipids. Since elongation of fatty acids from C16 to C18 has re
Externí odkaz:
https://doaj.org/article/eead95e827204c9c839e6b1f5290d59a
Autor:
Cristina Cadenas, Kathrin Gianmoena, Nina Gasparoni, Adelina Jashari, Philipp Gabrys, Ahmed Ghallab, Katharina Grgas, Jörn Walter, Jan Hengstler
Publikováno v:
Zeitschrift für Gastroenterologie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7d1babe9d1aa3aab862eac82cf87ebf
https://doi.org/10.1055/s-0041-1740734
https://doi.org/10.1055/s-0041-1740734
Autor:
Gilles Gasparoni, Rosemarie Marchan, Heiko Hayen, Philipp Gabrys, Daniel Seehofer, Ahmed Ghallab, Thomas S. Weiss, Kathrin Gianmoena, Peter Boor, Katharina Grgas, Georg Damm, Tobias S. Schiergens, Eduardo Salido, Jörg Reinders, Patricio Godoy, Cristina Cadenas, Jörn Walter, Karolina Edlund, Clivia Lisowski, Nina Gasparoni, Alexander Schriewer, Karl Nordström, Christian A. Hudert, Philip Rosenstiel, Maren Falk-Paulsen, Jan G. Hengstler, Adelina Jashari, Manga Motrapu, Hans-Joachim Anders, Peter L.M. Jansen
Publikováno v:
Cell reports, 36(8):109526
Cell Reports, Vol 36, Iss 8, Pp 109526-(2021)
Cell Reports, 36(8):109526. Cell Press
Cell Reports, Vol 36, Iss 8, Pp 109526-(2021)
Cell Reports, 36(8):109526. Cell Press
Summary Epigenetic modifications (e.g. DNA methylation) in NAFLD and their contribution to disease progression and extrahepatic complications are poorly explored. Here, we use an integrated epigenome and transcriptome analysis of mouse NAFLD hepatocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f571b52cf8f5b02c6d64ba43ac054af0
https://www.sciencedirect.com/science/article/pii/S2211124721009578?via=ihub#app2
https://www.sciencedirect.com/science/article/pii/S2211124721009578?via=ihub#app2
Autor:
Kathrin Gianmoena, Juliane Pokorny, Frank Lammert, Sonja M. Kessler, Rolf Mueller, Yvette Simon, Johannes Haybaeck, Katja Gemperlein, Cristina Cadenas, Volkhard Helms, Rainer M. Bohle, Ahmad Barghash, Vincent Zimmer, Jan G. Hengstler, Alexandra K. Kiemer, Nico van Rooijen
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 5762-5773 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 4; Pages: 5762-5773
International Journal of Molecular Sciences, 15(4), 5762-5773. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Kessler, S M, Simon, Y, Gemperlein, K, Gianmoena, K, Cadenas, C, Zimmer, V, Pokorny, J, Barghash, A, Helms, V, van Rooijen, N, Bohle, R M, Lammert, F, Hengstler, J G, Mueller, R, Haybaeck, J & Kiemer, A K 2014, ' Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma ', International Journal of Molecular Sciences, vol. 15, no. 4, pp. 5762-5773 . https://doi.org/10.3390/ijms15045762
International Journal of Molecular Sciences; Volume 15; Issue 4; Pages: 5762-5773
International Journal of Molecular Sciences, 15(4), 5762-5773. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Kessler, S M, Simon, Y, Gemperlein, K, Gianmoena, K, Cadenas, C, Zimmer, V, Pokorny, J, Barghash, A, Helms, V, van Rooijen, N, Bohle, R M, Lammert, F, Hengstler, J G, Mueller, R, Haybaeck, J & Kiemer, A K 2014, ' Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma ', International Journal of Molecular Sciences, vol. 15, no. 4, pp. 5762-5773 . https://doi.org/10.3390/ijms15045762
Non-alcoholic steatohepatitis (NASH) represents a risk factor for the development of hepatocellular carcinoma (HCC) and is characterized by quantitative and qualitative changes in hepatic lipids. Since elongation of fatty acids from C16 to C18 has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f4e1c74615432c6c859998806ab618
Autor:
Saša Frank, Kathrin Gianmoena, Carsten Watzl, Alshaimaa Adawy, Jan G. Hengstler, Katharina Grgas, Joanna Stewart, Cheng Cheng Zhang, Rosemarie Marchan, Fredrik Pontén, Birte Hellwig, Heiko Hayen, Alexander Schriewer, Cristina Cadenas, Dennis Franckenstein, Jörg Rahnenführer, Maren Claus, Michaela S. Lesjak, Patrick Micke, Sonja Vosbeck, Annika Glotzbach, Sonja Thaler, Karolina Edlund, Katrin Madjar, Adil Mardinoglu, Marcus Schmidt, Heiko U. Käfferlein
Publikováno v:
International journal of cancer, 145(4):901-915
Cadenas, C, Vosbeck, S, Edlund, K, Grgas, K, Madjar, K, Hellwig, B, Adawy, A, Glotzbach, A, Stewart, J D, Lesjak, M S, Franckenstein, D, Claus, M, Hayen, H, Schriewer, A, Gianmoena, K, Thaler, S, Schmidt, M, Micke, P, Pontén, F, Mardinoglu, A, Zhang, C, Käfferlein, H U, Watzl, C, Frank, S, Rahnenführer, J, Marchan, R & Hengstler, J G 2019, ' LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer ', International Journal of Cancer, vol. 145, no. 4, pp. 901-915 . https://doi.org/10.1002/ijc.32138
International Journal of Cancer
Cadenas, C, Vosbeck, S, Edlund, K, Grgas, K, Madjar, K, Hellwig, B, Adawy, A, Glotzbach, A, Stewart, J D, Lesjak, M S, Franckenstein, D, Claus, M, Hayen, H, Schriewer, A, Gianmoena, K, Thaler, S, Schmidt, M, Micke, P, Pontén, F, Mardinoglu, A, Zhang, C, Käfferlein, H U, Watzl, C, Frank, S, Rahnenführer, J, Marchan, R & Hengstler, J G 2019, ' LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer ', International Journal of Cancer, vol. 145, no. 4, pp. 901-915 . https://doi.org/10.1002/ijc.32138
International Journal of Cancer
Endothelial lipase (LIPG) is a cell surface associated lipase that displays phospholipase A1 activity towards phosphatidylcholine present in high‐density lipoproteins (HDL). LIPG was recently reported to be expressed in breast cancer and to support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbe3d59641ddfcbd0139fa73f899671
https://eprints.soton.ac.uk/436970/
https://eprints.soton.ac.uk/436970/
Autor:
Karolina Edlund, Mikheil Gogiashvili, Jörg Rahnenführer, Kathrin Gianmoena, Rosemarie Marchan, Jan G. Hengstler, Alexander Brik, Jörg Lambert, Roland Hergenröder, Cristina Cadenas, Birte Hellwig, Jan T. Andersson, Katrin Madjar
Publikováno v:
Analytical and Bioanalytical Chemistry. 409:1591-1606
Metabolic perturbations resulting from excessive hepatic fat accumulation are poorly understood. Thus, in this study, leptin-deficient ob/ob mice, a mouse model of fatty liver disease, were used to investigate metabolic alterations in more detail. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62bb38b341c6f728540b0add5f63d987
https://doi.org/10.1007/s00216-016-0100-1
https://doi.org/10.1007/s00216-016-0100-1
Autor:
Cristina Cadenas, Wei Chen, Maibritt Mardahl, Karl Nordstroem, Stefan Wallner, Ria Baumgrass, Pawel Durek, Julia K. Polansky, Stefan Floess, Sven Olek, Sascha Tierling, Martin Karl, Boris A. Ratsch, Matthias Pink, Jörn Walter, Uta Syrbe, Alf Hamann, Kathrin Gianmoena
Publikováno v:
The Journal of Immunology. 197:3406-3414
E- and P-selectin ligands (E- and P-ligs) guide effector memory T cells into skin and inflamed regions, mediate the inflammatory recruitment of leukocytes, and contribute to the localization of hematopoietic precursor cells. A better understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50041fd5b359ac44cbd504e940c06f6
https://doi.org/10.4049/jimmunol.1502434
https://doi.org/10.4049/jimmunol.1502434
Autor:
Wolfgang Schmidt-Heck, Georg Damm, Seddik Hammad, Uta Dahmen, Steven Dooley, Rosemarie Marchan, Nils Blüthgen, Reinhard Guthke, Ahmed Ghallab, Thomas S. Weiss, Daniel Seehofer, Raymond Reif, G Campos, Rolf Gebhardt, Regina Stöber, Jan G. Hengstler, Umesh Chaudhari, Agata Widera, Karolina Edlund, Patricio Godoy, Agapios Sachinidis, Larissa Pütter, Kathrin Gianmoena, Olaf Dirsch, Ute Hofmann, Andreas K. Nussler, Kesavan Meganathan, Christoph Meyer, Cristina Cadenas, Jens M. Kelm, Wolfgang E. Thasler, René P. Zahedi
Publikováno v:
Archives of Toxicology
It is well known that isolation and cultivation of primary hepatocytes cause major gene expression alterations. In the present genome-wide, time-resolved study of cultivated human and mouse hepatocytes, we made the observation that expression changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06e246c871c92bffff56c0ec7e343cb
http://europepmc.org/articles/PMC5043005
http://europepmc.org/articles/PMC5043005