Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kathrin Freudenberger"'
Autor:
Kathrin Freudenberger
Publikováno v:
Current Issues in Sport Science, Vol 8, Iss 2 (2023)
Introduction Movement is the motor of young children’s overall development and must be recognized in all its facets and enabled and encouraged in various contexts. Kindergarten – as the first compulsory educational institution in Switzerland
Externí odkaz:
https://doaj.org/article/71920afc8ea84f3c97e6e40368d4f079
Publikováno v:
Kinder-und Jugendsportforschung in Deutschland – Bilanz und Perspektive ISBN: 9783658307752
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07f4b54dd1ca5b5907561de40b441eaa
https://doi.org/10.1007/978-3-658-30776-9_14
https://doi.org/10.1007/978-3-658-30776-9_14
Autor:
Anja Hoffmann, David D. Busath, Michaela Schmidtke, Dimitrios Kolokouris, Johanna Hutterer, Jun Wang, Kelly L. McGuire, Kathrin Freudenberger, Antonios Drakopoulos, Christina Tzitzoglaki, Günter Gauglitz, Chunlong Ma, Athina Konstantinidi, Antonios Kolocouris
Publikováno v:
ACS Medicinal Chemistry Letters. 9:198-203
[Image: see text] Recently, the binding kinetics of a ligand–target interaction, such as the residence time of a small molecule on its protein target, are seen as increasingly important for drug efficacy. Here, we investigate these concepts to expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723ac986327427b5ea6bfd2ece2cf80d
https://doi.org/10.1021/acsmedchemlett.7b00458
https://doi.org/10.1021/acsmedchemlett.7b00458
Autor:
Timothy A. Cross, Kathrin Freudenberger, Antonios Kolocouris, Anja Hoffmann, Ioannis Stylianakis, Ian Tietjen, Felix Kolarov, Anna K. Wright, David Fedida, Christina Tzitzoglaki, Günter Gauglitz, Michaela Schmidtke
Publikováno v:
J Med Chem
While aminoadamantanes are well-established inhibitors of the influenza A M2 proton channel, the mechanisms by which they are rendered ineffective against M2(S31N) are unclear. Solid state NMR, isothermal titration calorimetry, electrophysiology, ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bde8a912b66758bd58cd7aa7f928801
https://doi.org/10.1021/acs.jmedchem.6b01115
https://doi.org/10.1021/acs.jmedchem.6b01115
Autor:
Monika Fleischer, Andreas Horrer, Dieter P. Kern, Günter Gauglitz, Kathrin Freudenberger, Jonas Haas
Publikováno v:
Nanoscale. 9:17378-17386
We report on a compact and cost-effective integrated label-free biosensor configuration which is based on the refractive index sensitivity of the localized surface plasmon resonance (LSPR) of gold nanostructures. Aiming for compactification and minia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8269a25aaeb0dcd99011d83df2fbd356
https://doi.org/10.1039/c7nr04097k
https://doi.org/10.1039/c7nr04097k
Autor:
Antonios Kolocouris, Felix Kolarov, Kathrin Freudenberger, Paraskevi Gkeka, Zoe Cournia, Christos Liolios, Harris Ioannidis, Holger Gohlke, Christina Tzitzoglaki, Günter Gauglitz, Nadine Homeyer, Antonios Drakopoulos
Publikováno v:
Journal of Chemical Information and Modeling. 56:862-876
Adamantane derivatives, such as amantadine and rimantadine, have been reported to block the transmembrane domain (TM) of the M2 protein of influenza A virus (A/M2) but their clinical use has been discontinued due to evolved resistance in humans. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500930f123e6ae64ba87c1e66d4f1ccd
https://doi.org/10.1021/acs.jcim.6b00079
https://doi.org/10.1021/acs.jcim.6b00079
Publikováno v:
TrAC Trends in Analytical Chemistry. 79:257-268
The transplantation of a solid organ is always followed by a lifelong immunosuppressive therapy to guarantee the survival of the organ in the recipient. Immunosuppressive drugs have to be applied in order to preserve the graft and at last the patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b856f9e6afcc2024c3ba1876ab06bc6a
https://doi.org/10.1016/j.trac.2015.11.016
https://doi.org/10.1016/j.trac.2015.11.016
Publikováno v:
Bildungspotentiale des Fußballs ISBN: 9783658195014
Von dem globalen Phanomen Migration und seinen lokalen Auswirkungen ist auch der Sport in vielerlei Hinsicht betroffen. Sollen soziale Ungleichheiten uberwunden werden, liegt es nahe, Institutionalisierungsformen, Programme und Praxen im Hinblick auf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f811aa662e0038674b8f6f14fa644c85
https://doi.org/10.1007/978-3-658-19502-1_4
https://doi.org/10.1007/978-3-658-19502-1_4
Autor:
Gianluca Persichetti, Daniel Carney, G. Porro, Ambra Giannetti, Ana B. Descalzo, Francesco Baldini, Genni Testa, Heike Bittersohl, Marcel Berner, Sara Tombelli, Chiara Berrettoni, Kathrin Freudenberger, Cosimo Trono, Francesca Salis, Urs Hilbig, Immacolata Angelica Grimaldi, Günter Gauglitz, Holger Becker, Peter B. Luppa, Claudia Gärtner, Guillermo Orellana, Markus B. Schubert, Paulo P. Freitas, Mark T. O'Connell, Romeo Bernini
Publikováno v:
Optical Diagnostics and Sensing XVII: Toward Point-of-Care Diagnostics.
A novel therapeutic drug monitoring point of care testing (POCT) optical device for the detection of immunosuppressants in transplanted patients was designed and tested, with the body interface constituted by an intravascular microdialysis catheter (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91717bf168da1c766673d0981a9a6d9f
https://doi.org/10.1117/12.2255623
https://doi.org/10.1117/12.2255623
Autor:
Antonios Drakopoulos, Jun Wang, Antonios Kolocouris, Anja Hoffmann, Michaela Schmidtke, Guenter Gauglitz, Chulong Ma, Kathrin Freudenberger, Christina Tzitzoglaki, Yanmei Hu
Recent findings from solid state NMR (ssNMR) studies suggested that the (R)-enantiomer of rimantadine binds to the full M2 protein with higher affinity than the (S)-enantiomer. Intrigued by these findings, we applied functional assays, such as antivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ff63d942413d356dbec40ce2d63663
https://europepmc.org/articles/PMC5312807/
https://europepmc.org/articles/PMC5312807/