Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathrin E. Martz"'
Publikováno v:
Frontiers in Pharmacology, Vol 1 (2010)
Background:Equine dysautonomia or equine grass sickness (EGS), as it is more commonly known, is a usually fatal disease of equids of uncertain aetiology, although associated with grazing, that affects the autonomic and enteric nervous system. Lowered
Externí odkaz:
https://doaj.org/article/acd32acad69a4a7c825bced0632dd79c
Autor:
Daniel Rauh, Benjamin Baur, Márcia Inês Goettert, Stefan Laufer, Kirsten Storch, André Richters, Kathrin E. Martz
Publikováno v:
Journal of Medicinal Chemistry. 56:8561-8578
Five series of metabolically stable disubstituted dibenzo[b,e]oxepin-11(6H)-ones were synthesized and tested in a p38α enzyme assay for their inhibition of tumor necrosis factor-α (TNF-α) release in human whole blood. Compared to the monosubstitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca37bfa29c5bb75303533f0888d9c91
https://doi.org/10.1021/jm401276h
https://doi.org/10.1021/jm401276h
Autor:
Márcia Inês Goettert, Daniel Rauh, Verena Schattel, Kathrin E. Martz, Stefan Laufer, Svenja C. Mayer-Wrangowski, Benjamin Baur, Angelika Dorn
Publikováno v:
Journal of medicinal chemistry. 55(17)
The p38 MAP kinase is a key player in signaling pathways regulating the biosynthesis of inflammatory cytokines. Small molecule p38 inhibitors suppress the production of these cytokines. Therefore p38 is a promising drug target for novel anti-inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4909598d78a4f736479ae0c9dbe7d265
https://pubmed.ncbi.nlm.nih.gov/22897496
https://pubmed.ncbi.nlm.nih.gov/22897496