Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kathrin D Geiger"'
Autor:
Roberta Galli, Ortrud Uckermann, Elisabeth F Andresen, Kathrin D Geiger, Edmund Koch, Gabriele Schackert, Gerald Steiner, Matthias Kirsch
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110295 (2014)
Multiphoton imaging has evolved as an indispensable tool in cell biology and holds prospects for clinical applications. When addressing endogenous signals such as coherent anti-Stokes Raman scattering (CARS) or second harmonic generation, it requires
Externí odkaz:
https://doaj.org/article/e57c8b261e6d45df9360ba065758f6b7
Autor:
Ortrud Uckermann, Roberta Galli, Sandra Tamosaityte, Elke Leipnitz, Kathrin D Geiger, Gabriele Schackert, Edmund Koch, Gerald Steiner, Matthias Kirsch
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107115 (2014)
Coherent anti-Stokes Raman scattering (CARS) microscopy provides fine resolution imaging and displays morphochemical properties of unstained tissue. Here, we evaluated this technique to delineate and identify brain tumors.Different human tumors (glio
Externí odkaz:
https://doaj.org/article/828044b8cada45fda71b584a47e8cced
Autor:
Allison L Stelling, Deirdre Toher, Ortrud Uckermann, Jelena Tavkin, Elke Leipnitz, Julia Schweizer, Holger Cramm, Gerald Steiner, Kathrin D Geiger, Matthias Kirsch
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58332 (2013)
In this work, the infrared (IR) spectra of living neural cells in suspension, native brain tissue, and native brain tumor tissue were investigated. Methods were developed to overcome the strong IR signal of liquid water so that the signal from the ce
Externí odkaz:
https://doaj.org/article/6c914b4e37984c109138586fac3646a1
Autor:
Amin, Derouiche, Kathrin D, Geiger
Publikováno v:
International Journal of Molecular Sciences
Astrocytes are increasingly perceived as active partners in physiological brain function and behaviour. The structural correlations of the glia–synaptic interaction are the peripheral astrocyte processes (PAPs), where ezrin and radixin, the two ast
Autor:
Hella Luksch, Katja S. Brocke, Andrzej Stepulak, Chrysanthy Ikonomidou, Jenny Marzahn, Kathrin D. Geiger, Christian Staufner, Achim Temme, Gabriele Schackert
Publikováno v:
Scopus-Elsevier
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS). Experimental evidence indicates that glutamate receptor antagonists may limit tumor growth. This study explores expression of glutamate receptor subunit
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 65:87-96
The actin-binding protein ezrin is associated with cellular shape changes, motility, tumor invasion, and lymphocyte activation. We have earlier shown that ezrin immunoreactivity (IR) is faintly present in normal astrocytes but increased in malignant
Autor:
Jörg Kreuter, Sebastian C.J. Steiniger, Alexander S. Khalansky, Reiner Uhl, Zoya S Smirnova, I. N. Skidan, Svetlana Gelperina, Alexey I Bobruskin, Martin Kock, Sergey E Severin, Kathrin D. Geiger
Publikováno v:
International Journal of Cancer. 109:759-767
Glioblastomas belong to the most aggressive human cancers with short survival times. Due to the blood-brain barrier, they are mostly inaccessible to traditional chemotherapy. We have recently shown that doxorubicin bound to polysorbate-coated nanopar
Autor:
John C. Reed, Floyd E. Bloom, Deepak Gurushanthaiah, Gail Lewandowski, Nora Sarvetnick, Edward L. Howes, Kathrin D. Geiger
Publikováno v:
Proceedings of the National Academy of Sciences. 92:3411-3415
The mechanisms responsible for cytokine-mediated antiviral effects are not fully understood. We approached this problem by studying the outcome of intraocular herpes simplex (HSV) infection in transgenic mice that express interferon gamma in the phot
Publikováno v:
Journal of Virology. 68:5556-5567
Transgenic (rho gamma) mice provide a model for studying the influence of gamma interferon (IFN-gamma) produced in the eye on ocular and cerebral viral infection. To establish this model, we injected BALB/c- and C57BL/6-derived transgenic and nontran