Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Kathrin, Sutter"'
Autor:
Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Mike Hasenberg, Bernd Walkenfort, Martin Trippler, Jonas Schuhenn, Kathrin Sutter, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Hepatitis B virus (HBV)-transgenic mice exhibit competent innate immunity and are therefore an ideal model for considering intrinsic or cell-based mechanisms in HBV pathophysiology. A highly replicative model that has been little used, let a
Externí odkaz:
https://doaj.org/article/d8033cbdd44a4c2e8375ba24f2d4d013
Autor:
Philine Steinbach, Eva Pastille, Lara Kaumanns, Alexandra Adamczyk, Kathrin Sutter, Wiebke Hansen, Ulf Dittmer, Jan Buer, Astrid M Westendorf, Torben Knuschke
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011982 (2024)
Influenza A virus (IAV) can cause severe respiratory infection leading to significant global morbidity and mortality through seasonal epidemics. Likewise, the constantly increasing number of cancer diseases is a growing problem. Nevertheless, the und
Externí odkaz:
https://doaj.org/article/a63e2a8e22f64398969f9161ce87c646
Autor:
Zehra Karakoese, Vu-Thuy Khanh Le-Trilling, Jonas Schuhenn, Sandra Francois, Mengji Lu, Jia Liu, Mirko Trilling, Daniel Hoffmann, Ulf Dittmer, Kathrin Sutter
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTDuring viral infections, type I interferons (IFN) are induced and play a key role in counteracting initial viral spread. Twelve different human IFNα subtypes exist that bind the same receptor; however, they elicit unique host responses and d
Externí odkaz:
https://doaj.org/article/377a20afbe4547f6abdae03324ad4c6a
Autor:
Anna Malyshkina, Wibke Bayer, Philip Podschwadt, Lucas Otto, Zehra Karakoese, Kathrin Sutter, Kirsten Bruderek, Baoxiao Wang, Kerry J Lavender, Mario L Santiago, Pia Madeleine Leipe, Carina Elsner, Stefan Esser, Sven Brandau, Matthias Gunzer, Ulf Dittmer
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011725 (2023)
Antiretroviral therapy (ART) transformed HIV from a life-threatening disease to a chronic condition. However, eliminating the virus remains an elusive therapy goal. For several decades, Friend virus (FV) infection serves as a murine model to study re
Externí odkaz:
https://doaj.org/article/a81ed88024bb4e859ce8d252a4270370
Autor:
Jaana Westmeier, Annika Brochtrup, Krystallenia Paniskaki, Zehra Karakoese, Tanja Werner, Kathrin Sutter, Sebastian Dolff, Andreas Limmer, Daniela Mittermüller, Jia Liu, Xin Zheng, Tetiana Koval, Igor Kaidashev, Marc Moritz Berger, Frank Herbstreit, Thorsten Brenner, Oliver Witzke, Mirko Trilling, Mengji Lu, Dongliang Yang, Nina Babel, Timm Westhoff, Ulf Dittmer, Gennadiy Zelinskyy
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused millions of COVID-19 cases and deaths worldwide. Severity of pulmonary pathologies and poor prognosis were reported to be associated with the activation non-virus-specific bystander
Externí odkaz:
https://doaj.org/article/d3fe19df29384cfaa03d76a182446adf
Publikováno v:
Viruses, Vol 16, Iss 3, p 364 (2024)
Type I interferons (IFN), immediately triggered following most viral infections, play a pivotal role in direct antiviral immunity and act as a bridge between innate and adaptive immune responses. However, numerous viruses have evolved evasion strateg
Externí odkaz:
https://doaj.org/article/f8cd6651c266487883a1108555ba73f3
Autor:
Christina Wenzek, Philine Steinbach, Florian Wirsdörfer, Kathrin Sutter, Julia D. Boehme, Robert Geffers, Robert Klopfleisch, Dunja Bruder, Verena Jendrossek, Jan Buer, Astrid M. Westendorf, Torben Knuschke
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105540- (2022)
Summary: CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of CD47 on immune cells seemed to disturb
Externí odkaz:
https://doaj.org/article/13de89e0b0ca48f9bd746945964e9b6d
Autor:
Helene Sertznig, Fabian Roesmann, Alexander Wilhelm, Delia Heininger, Barbara Bleekmann, Carina Elsner, Mario Santiago, Jonas Schuhenn, Zehra Karakoese, Yvonne Benatzy, Ryan Snodgrass, Stefan Esser, Kathrin Sutter, Ulf Dittmer, Marek Widera
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Efficient HIV-1 replication depends on balanced levels of host cell components including cellular splicing factors as the family of serine/arginine-rich splicing factors (SRSF, 1–10). Type I interferons (IFN-I) play a crucial role in the innate imm
Externí odkaz:
https://doaj.org/article/7a4ac982719d42a183ae0f8d9778d433
Autor:
Yasmin Schmitz, Mara Schwerdtfeger, Jaana Westmeier, Elisabeth Littwitz-Salomon, Mira Alt, Leonie Brochhagen, Adalbert Krawczyk, Kathrin Sutter
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Type I interferons (IFNs) present the first line of defense against viral infections, providing antiviral, immunomodulatory and antiproliferative effects. The type I IFN family contains 12 IFNα subtypes and IFNβ, and although they share the same re
Externí odkaz:
https://doaj.org/article/84318269771642d2ac87447ec0a28595
Autor:
Xiaohong Xie, Zehra Karakoese, Dilhumare Ablikim, Julia Ickler, Jonas Schuhenn, Xiaoqing Zeng, Xuemei Feng, Xuecheng Yang, Ulf Dittmer, Dongliang Yang, Kathrin Sutter, Jia Liu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic hepatitis B virus (HBV) infection continues to be a major health problem worldwide and remains hard to be cured. Therapy with interferon (IFN) α is an important method for the clinical treatment of chronic hepatitis B. IFNα exhibits direct
Externí odkaz:
https://doaj.org/article/583572b6e7c64776b2fc72452eeba02e