Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kathleen Yates"'
Supplementary Data from CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Autor:
Kwok-Kin Wong, Nathanael S. Gray, David A. Barbie, Geoffrey I. Shapiro, Haribabu Arthanari, Norman E. Sharpless, W. Nicholas Haining, Jerome Ritz, Gordon J. Freeman, Sangeetha Palakurthi, Raphael Bueno, Genevieve M. Boland, Viswanath Gunda, Sareh Parangi, Jochen H. Lorch, William G. Richards, Jay C. Strum, Patrick J. Roberts, Eric Haines, Amanda J. Rode, Megan E. Cavanaugh, Ting Chen, Peng Gao, Hua Zhang, Yanxi Zhang, Annan Yang, Lauren E. Bufe, Max M. Quinn, Ashley A. Merlino, Patrick H. Lizotte, John E. Bisi, Jessica A. Sorrentino, Grit S. Herter-Sprie, Chensheng W. Zhou, Michaela Bowden, Cloud P. Paweletz, Elena Ivanova, Amir R. Aref, Hongye Liu, Wei Huang, Sandeep Chhabra, Kathleen Yates, Ruben Dries, Shuai Li, Russell W. Jenkins, Eric S. Wang, Jiehui Deng
Figure S1. Characterization of cells and CDK4/6 inhibitors; Figure S2. CDK6 phosphorylates serine residues of the regulatory domain of NFAT4 (NFATc3); Figure S3. Analysis of lung tumor immune infiltrates after CDK4/6 inhibition from KrasG12D (Kras),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a01c7e72b06ed917fff29065c873f6
https://doi.org/10.1158/2159-8290.22531849.v1
https://doi.org/10.1158/2159-8290.22531849.v1
Autor:
Kathleen McGuire, Christina Baumgartner, Carey Backus, Rebecca Mathew, Kelly Klinge, Joseph Klahn, Prasanthi Geda, Kyle Halliwill, Jacqueline Aguado, Liang Mu, Ryan Duggan, Cara Hrusch, Elliot Farney, Zhaoming Xiong, Marinka Bulic, Patricia Trusk, Loren Lasko, Hakimeh Ebrahimi-Nik, Kathleen Yates, Robert Manguso, Keith Hamel, Marcia Paddock, Jennifer Frost, Philip Kym
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Bryan Iorgulescu, Neil Ruthen, Ryuhjin Ahn, Eleni Panagioti, Prafulla Gokhale, Martha Neagu, Maria Speranza, Benjamin Eschle, Kara Soroko, Raziye Piranlioglu, Meenal Datta, Shanmugarajan Krishnan, Kathleen Yates, Gregory Baker, Rakesh Jain, Mario Suva, Donna Neuberg, Forest White, E. Chiocca, Gordon Freeman, Arlene Sharpe, Catherine Wu, David Reardon
Publikováno v:
Cancer Research. 83:2990-2990
The GL261-luc2 and CT2A-luc syngeneic tumor lines are frequently used as immunocompetent orthotopic mouse models of human glioblastoma (huGBM), but demonstrate distinct differences in response to immune checkpoint blockade. Whereas GL261-luc2 is read
Autor:
Prakash K Gupta, Jernej Godec, David Wolski, Emily Adland, Kathleen Yates, Kristen E Pauken, Cormac Cosgrove, Carola Ledderose, Wolfgang G Junger, Simon C Robson, E John Wherry, Galit Alter, Philip J R Goulder, Paul Klenerman, Arlene H Sharpe, Georg M Lauer, W Nicholas Haining
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005177 (2015)
Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit immunity to chronic viral infection. Defining novel markers of exhaustion is important both for identifying and potentially reversing T cell exhaustion. H
Externí odkaz:
https://doaj.org/article/a33577d938d04eef98014e4ae8a823b4
Autor:
Natalie B Collins, Rose Al Abosy, Brian Miller, Kevin Bi, Robert Manguso, Kathleen Yates, W. Nicholas Haining
Publikováno v:
The Journal of Immunology. 202:58.17-58.17
Oncogenes act in a cell-intrinsic way to promote tumorigenesis. Whether oncogenes also have a cell-extrinsic effect on suppressing the immune response to cancer is less well understood. Here we use an in vivo screen of known cancer-associated somatic
Autor:
Ian Reid, Linda Treliving, Alison Lowit, Malcolm Kay, Michael Forrester, Stephen Arcari, Philip Crockett, Andrew Moskowitz, Kathleen Yates
Publikováno v:
Lowit, A, Treliving, L, Arcari, S, Yates, K, Kay, M, Crockett, P, Forrester, M, Reid, I & Moskowitz, A 2010, ' Gender and the psychological effects of childhood sexual abuse: A replication of Gold, Lucenko, Elhai, Swingle, & Sellers (1999) ', Maltrattamento e Abuso all'Infanzia, vol. 12, no. 2, pp. 61-72 . https://doi.org/10.3280/MAL2010-002005
While childhood sexual abuse (CSA) has been linked to a wide range of subsequent psychological problems in women, relatively few studies have included male CSA survivors; those that have typically have been limited by small sample sizes and/or failin
Publikováno v:
British Journal of Psychotherapy. 18:68-88
Patients with borderline and other severe personality disorders take up a disproportionate amount of time from psychiatric, accident and emergency and community services. The Edinburgh Project was commissioned to examine the process and outcome of ti
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 979
Genome-wide gene expression analysis has become a very powerful routine tool for the study of distinct differentiation states. However, the examination of total populations of cells that contain high levels of heterogeneity, such as the total CD8(+)
Autor:
Pablo Penaloza-MacMaster, Daniel Barber, E. Wherry, Nicholas Provine, Jeffrey E. Teigler, Lily Parenteau, Stephen Blackmore, Erica Borducchi, Rafael Larocca, Kathleen Yates, Hao Shen, W. Haining, Rami Sommerstein, Daniel Pinschewer, Rafi Ahmed, Dan Barouch
Publikováno v:
The Journal of Immunology. 194:74.9-74.9
CD4 T cells promote memory immune responses, but it is unclear whether vaccine-induced CD4 T cells contribute to immune protection. We interrogated if virus-specific CD4 T cells would protect mice against infection with chronic lymphocytic choriomeni
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