Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathleen Wynants"'
Effect of Montelukast on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Volunteers
Autor:
Barry J. Gertz, Marleen Depré, Amanda Freeman, Sherry D. Holland, Kathleen Wynants, Paul J. De Schepper, René Verbesselt, Peggy H. Wong, Inge De Lepeleire, Jef Arnout, Anne Van Hecken
Publikováno v:
The Journal of Clinical Pharmacology. 39:495-500
Montelukast, a cysteinyl leukotriene receptor antagonist, is being developed for the treatment of asthma and related diseases. This study was designed to evaluate whether montelukast at clinically used dosage levels would interfere with the anticoagu
Autor:
Peggy H. Wong, Barry J. Gertz, Jef Arnout, Marleen Depré, Anne Van Hecken, Wesley Tanaka, David L. Ebel, Kathleen Wynants, Paul J. De Schepper, Aimee Dallob, Inge De Lepeleire, Agnes Buntinx, Jules I. Schwartz
Publikováno v:
Journal of clinical pharmacology. 40(10)
Steady-state inhibitory activity of rofecoxib (Vioxx) on COX-2 versus COX-1 was compared with that of commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) in 76 healthy volunteers randomized to placebo, rofecoxib 12.5 mg qd, rofecoxib 25 mg qd
Autor:
Jozef Arnout, M Depre, Alfons Verbruggen, H Vanbilloen, P Vanhove, P. J. De Schepper, A. Van Hecken, R Cariou, Kathleen Wynants
Publikováno v:
Drug metabolism and drug interactions. 14(3)
The effect of clopidogrel, a potent inhibitor of platelet aggregation, on naproxen-induced faecal blood loss was investigated in 30 healthy volunteers in a randomized, double-blind, placebo-controlled, two parallel treatment groups study. All subject