Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathleen Wojnoonski"'
Autor:
Jiyung Shin, Ming He, Yufei Liu, Silvana Paredes, Lidia Villanova, Katharine Brown, Xiaolei Qiu, Noushin Nabavi, Mary Mohrin, Kathleen Wojnoonski, Patrick Li, Hwei-Ling Cheng, Andrew J. Murphy, David M. Valenzuela, Hanzhi Luo, Pankaj Kapahi, Ronald Krauss, Raul Mostoslavsky, George D. Yancopoulos, Frederick W. Alt, Katrin F. Chua, Danica Chen
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 654-665 (2013)
Nonalcoholic fatty liver disease is the most common chronic liver disorder in developed countries. Its pathogenesis is poorly understood, and therapeutic options are limited. Here, we show that SIRT7, an NAD+-dependent H3K18Ac deacetylase, functions
Externí odkaz:
https://doaj.org/article/998f1e97082c46e383fcf42ca235d917
Autor:
Ronald M. Krauss, Lara M. Mangravite, Sally Chiu, Nathalie Bergeron, Robin S. Rawlings, Kathleen Wojnoonski
Publikováno v:
The Journal of Nutrition. 141:2180-2185
Previous studies have shown that multiple features of atherogenic dyslipidemia are improved by replacement of dietary carbohydrate with mixed sources of protein and that these lipid and lipoprotein changes are independent of dietary saturated fat con
Autor:
J. Casey Geaney, Sue Naim, Kathleen Wojnoonski, Ronald M. Krauss, David B. Karpf, Wang Xueyan, Brian K. Roberts, Yun-Jung Choi
Publikováno v:
Atherosclerosis. 220(2)
a b s t r a c t Objective: Determine the effects of treatment with a selective PPAR- agonist ± statin on plasma lipopro- tein subfractions in dyslipidemic individuals. Methods: Ion mobility analysis was used to measure plasma concentrations of subfr
Autor:
Achim A. Jungbluth, Elyn Riedel, Keith Vosseller, Kathleen Wojnoonski, James P. Allison, Chulho Kang, Kevin Larimore, Peter A. Savage
Publikováno v:
Science (New York, N.Y.). 319(5860)
Substantial evidence exists that many tumors can be specifically recognized by CD8 + T lymphocytes. The definition of antigens targeted by these cells is paramount for the development of effective immunotherapeutic strategies for treating human cance
Publikováno v:
Genomics. (6):841-845
In the past decade, the fundamental importance and therapeutic potential of costimulatory signals for lymphocyte activation have spurred a large amount of work in immunology, infection, cancer, autoimmune diseases, etc. However, the mechanisms behind
Autor:
Jiyung Shin, Yufei Liu, Ronald M. Krauss, Katharine Brown, Pankaj Kapahi, David M. Valenzuela, Katrin F. Chua, Kathleen Wojnoonski, Patrick Wai-Lun Li, Ming He, Frederick W. Alt, Andrew J. Murphy, Hanzhi Luo, Mary Mohrin, Danica Chen, Raul Mostoslavsky, Lidia Villanova, Silvana Paredes, Noushin Nabavi, George D. Yancopoulos, Xiaolei Qiu, Hwei-Ling Cheng
Publikováno v:
Cell Reports, Vol 5, Iss 5, p 1479 (2013)
Cell Reports, Vol 5, Iss 3, Pp 654-665 (2013)
Cell Reports, Vol 5, Iss 3, Pp 654-665 (2013)
Summary Nonalcoholic fatty liver disease is the most common chronic liver disorder in developed countries. Its pathogenesis is poorly understood, and therapeutic options are limited. Here, we show that SIRT7, an NAD + -dependent H3K18Ac deacetylase,
Publikováno v:
Immunity. (3):401-413
The reported affinity differences between CD28 and CTLA-4 binding to B7-1 and B7-2 may serve to selectively regulate CD28 and CTLA-4 function by differentially recruiting and/or stabilizing these molecules at the immunological synapse. Here we show t