Regulatory T and B cells in pediatric Henoch–Schönlein purpura: friends or foes?

Autor: Anne Filleron, Renaud Cezar, Marc Fila, Nastassja Protsenko, Kathleen Van Den Hende, Eric Jeziorski, Bob Occean, Thierry Chevallier, Pierre Corbeau, Tu Anh Tran

Publikováno v: Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)

Abstract Background and objectives Henoch–Schönlein purpura (HSP) is the most common immunoglobulin A-mediated systemic vasculitis in childhood. We studied immune dysregulation in HSP by analyzing regulatory T (Treg), T helper 3 (Th3), and regulat

Externí odkaz: https://doaj.org/article/2c724640b3364b8a8feea68c02a75092

miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes

Autor: Anne-Marie Madec, Sophie Rome, Lucien Marchand, Nicole Fabien, C. Thivolet, Audrey Jalabert, Kathleen Van den Hende, Emmanuelle Meugnier, Marc Nicolino

Publikováno v: Journal of diabetes research
Journal of diabetes research, Hindawi Publishing Coporation, 2016, 2016, pp.1-7. ⟨10.1155/2016/1869082⟩
Journal of diabetes research, Hindawi Publishing Coporation, 2016, 2016, pp.1-7
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2016 (2016)
Journal Of Diabetes Research, 1-8. (2016)
Journal of diabetes research, 2016, 2016, pp.1-7. ⟨10.1155/2016/1869082⟩

Background.The use of miRNAs as biomarkers for Type 1 Diabetes (T1D) risk is attractive as T1D is usually diagnosed in front of acute symptoms. As miR-375 is highly expressed in the endocrine pancreas, we postulated that its circulating level might r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3989a33441cff8f908ec5d7af694cf0d
https://doi.org/10.1155/2016/1869082