Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Kathleen Uhl"'
Autor:
Kathleen Uhl, Robert Lionberger
Publikováno v:
Clinical pharmacology and therapeutics. 105(2)
Autor:
Kathleen, Uhl, John R, Peters
Publikováno v:
American family physician. 97(11)
Publikováno v:
Clinical Pharmacology & Therapeutics. 91:153-157
Publikováno v:
Expert Review of Clinical Pharmacology. 4:453-466
The requirement to establish safety of drugs prior to marketing has been in place since 1938 by the US Food, Drug and Cosmetic Act and is by no means a new concept. The efficacy regulations were enacted in 1962 via the Kefauver-Harris Amendment and t
Autor:
Robert Kleiman, Jay W. Mason, Peter R. Kowey, J. Rick Turner, Kathleen Uhl, Mitchell W. Krucoff, Sherene S. Min, Christopher Newton-Cheh, John Finkle, Robert Pordy, Ivo Hynie, Alex Phipps, Adel Nada, Tara L. Dimino, Shari L. Targum, Colette Strnadova
Publikováno v:
American Heart Journal. 159:716-729
This white paper, prepared by members of the Cardiac Safety Research Consortium, discusses several important issues regarding the evaluation of ventricular arrhythmias in early clinical pharmacology trials and their potential consequences for later c
Publikováno v:
Clinical Pharmacology & Therapeutics, 86(4), 362-365. Nature Publishing Group
Approximately 3% of pregnant women take antidepressant medications. Information on the impact of antidepressants on short- and long-term maternal and offspring outcomes is highly desirable but neglected. The position that the dearth of treatment info
Publikováno v:
Clinical Pharmacology & Therapeutics. 83:192-195
Our nationwide bioinformatics infrastructure used to detect important sex differences associated with medical product use is antiquated. The Food and Drug Administration (FDA) has embarked on an ambitious bioinformatics modernization effort that will
Autor:
Dulce, Obias-Manno, Pamela E, Scott, Joseph, Kaczmarczyk, Margaret, Miller, Ellen, Pinnow, Lynda, Lee-Bishop, Michelle, Jones-London, Kennerly, Chapman, Deborah, Kallgren, Kathleen, Uhl
Publikováno v:
Journal of Women's Health. 16:807-817
In 1994, the Food and Drug Administration Office of Women's Health (FDA-OWH) was created to provide leadership and policy direction for the Agency regarding issues of women's health. Within its first year, the FDA-OWH established a science program fo
Publikováno v:
Pharmacoepidemiology and Drug Safety. 16:337-348
According to the March of Dimes, approximately 4% (1/28) of babies are born in the US each year with a birth defect. For the majority of birth defects the etiology is unknown, although chemicals, including drug exposures, probably account for less th
Publikováno v:
Obstetrics & Gynecology. 107:1120-1138
Over ten million women are either pregnant or lactating in the United States at any time. The risks of medication use for these women are unique. In addition to normal physiologic changes that alter the pharmacokinetics of drugs, there is the concern