Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kathleen Schostack"'
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
XLS file, 33K, Summary of RG7212 monotherapy and combination antitumor efficacy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0c5a629ee9bc5fed14a6ed7fd44e46
https://doi.org/10.1158/1078-0432.22448573.v1
https://doi.org/10.1158/1078-0432.22448573.v1
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
PDF file, 306K, RG7212 antitumor efficacy and characterization of tumor models used to assess RG7212 antitumor efficacy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2fcb229203249546d5c937e19f2292
https://doi.org/10.1158/1078-0432.22448591
https://doi.org/10.1158/1078-0432.22448591
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
PDF file, 771K, TWEAK promotes proliferation and survival signaling with minimal effect on cell viability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb42dde293f8d35c357e36d48188a019
https://doi.org/10.1158/1078-0432.22448582
https://doi.org/10.1158/1078-0432.22448582
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
PDF file, 132K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af5282726384c7c102eeb1081c033b3
https://doi.org/10.1158/1078-0432.22448579
https://doi.org/10.1158/1078-0432.22448579
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
Purpose: To explore the role of TWEAK in tumor growth and antitumor immune response and the activity and mechanism of RG7212, an antagonistic anti-TWEAK antibody, in tumor models.Experimental Design: TWEAK-induced signaling and gene expression were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c65786e9a54259bdc5aff3792cf08a0
https://doi.org/10.1158/1078-0432.c.6521432
https://doi.org/10.1158/1078-0432.c.6521432
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
XLS file, 193K, Sorted Affymetrix gene array data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136d2718cab2c031aaa70ba473ce60aa
https://doi.org/10.1158/1078-0432.22448570.v1
https://doi.org/10.1158/1078-0432.22448570.v1
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
PDF file, 29K, Lead antibodies have identical binding properties and neutralizing activities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395b97f93120c836ca1bcd8e3d258654
https://doi.org/10.1158/1078-0432.22448576
https://doi.org/10.1158/1078-0432.22448576
Autor:
Mary Simcox, Hy Levitsky, Mark DeMario, Suzana Vega-Harring, David Geho, Saumya Pant, Jian-Ping Tang, Windy Berkofsky-Fessler, Jim Rosinski, Kathryn Packman, Xiaoqian Wang, Denise Biondi, Theresa Truitt, Tai-An Lin, Holly Hilton, Kathleen Schostack, Tom Nevins, Melissa Smith, Hua Zhong, Leopoldo Luistro, Xuefeng Yin
PDF file, 176K, Assessment of baseline gene expression in RG7212 responders and non-responders in qPCR array.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f2d9906faef13e0beb9151c9da134b
https://doi.org/10.1158/1078-0432.22448585.v1
https://doi.org/10.1158/1078-0432.22448585.v1
Autor:
Fei Su, Gideon Bollag, David Heimbrook, Mary Ellen Simcox, Kathleen Schostack, Joseph F. Grippo, Richard Lee, Sylvia Zhao, Stanley Kolis, Raman Iyer, Zenaida Go, Kathryn Packman, Kenneth Kolinsky, Brian Higgins, Hong Yang
The BRAFV600E mutation is common in several human cancers, especially melanoma. RG7204 (PLX4032) is a small-molecule inhibitor of BRAFV600E kinase activity that is in phase II and phase III clinical testing. Here, we report a preclinical characteriza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de9b3ef352a4f9b3dcb4d341d3d7b67c
https://doi.org/10.1158/0008-5472.c.6500097.v1
https://doi.org/10.1158/0008-5472.c.6500097.v1
Autor:
Fei Su, Gideon Bollag, Brian Lestini, David Heimbrook, Scott Kopetz, Mary Ellen Simcox, Kathleen Schostack, Richard J. Lee, William D. Bradley, Kathryn Packman, Kenneth Kolinsky, Brian Higgins, Hong Yang
PDF file - 61K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1bc4d4a0aab37d059eea236081eb6d
https://doi.org/10.1158/0008-5472.22392525.v1
https://doi.org/10.1158/0008-5472.22392525.v1