Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kathleen Saavedra"'
Autor:
Pamela Seron, Daniela Gómez-Pérez, Edgardo Opazo-Díaz, Maria Jose Oliveros, Maria Francisca Contreras, Alejandra Salinas, Omar Andrade-Mayorga, Gabriel Nasri Marzuca-Nassr, Kathleen Saavedra, Cinthya Espejo, Sergio Muñoz, Fernando Lanas, Sherry L. Grace
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionComprehensive, hybrid cardiac rehabilitation (CR) models have been scantly investigated in heart failure (HF) populations, particularly in low-resource settings. CO-CREATION-HF aims to evaluate the effectiveness of such a model compared t
Externí odkaz:
https://doaj.org/article/945f0cd6c7f847dfb8a8be45727834e6
Autor:
Fernando Lanas, Nicolás Saavedra, Kathleen Saavedra, Montserrat Hevia, Pamela Seron, Luis A. Salazar
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundTemuco is a city in Southern Chile with elevated levels of air pollution (AP), mainly due to using wood as combustion throughout the cold season. The study aimed to assess the differences in cardiometabolic risk factors, estimated cardiovas
Externí odkaz:
https://doaj.org/article/7afc8b05e0514c63991fb3168b825c22
Autor:
Gabriel A. Rojas, Nicolás Saavedra, Cristian Morales, Kathleen Saavedra, Fernando Lanas, Luis A. Salazar
Publikováno v:
Toxics, Vol 11, Iss 10, p 844 (2023)
Exposure to polycyclic aromatic hydrocarbons (PAHs) present in air pollution increases cardiovascular risk. On the contrary, physical exercise is a widely used therapeutic approach to mitigate cardiovascular risk, but its efficacy in an environment o
Externí odkaz:
https://doaj.org/article/66d446daf37041e8964c8b8e4132baae
Autor:
Cristian Morales, Gabriel Rojas, Camilo Rebolledo, Marcelo Rojas-Herrera, Raúl Arias-Carrasco, Sara Cuadros-Orellana, Vinicius Maracaja-Coutinho, Kathleen Saavedra, Pamela Leal, Fernando Lanas, Luis A. Salazar, Nicolás Saavedra
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionIn recent years, several studies have evidenced the importance of the microbiome to host physiology as metabolism regulator, along with its potential role in triggering various diseases. In this study, we analyzed the gut microbiota in hy
Externí odkaz:
https://doaj.org/article/d091bb7edd4c48e3b20bad139911a86f
Autor:
Pía Loren, Nicolás Saavedra, Kathleen Saavedra, Nadine De Godoy Torso, Marília Berlofa Visacri, Patricia Moriel, Luis A. Salazar
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cisplatin (DDP) is a well-known anticancer drug used for the treatment of numerous human cancers in solid organs, including bladder, breast, cervical, head and neck squamous cell, ovarian, among others. Its most important mode of action is the DNA-pl
Externí odkaz:
https://doaj.org/article/8fa2c4a7244f48899e04a8168013ffcb
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Several studies show that statin therapy improves endothelial function by cholesterol-independent mechanisms called “pleiotropic effects.” These are due to the inhibition of the RhoA/ROCK kinase pathway, its inhibition being an attractive atherop
Externí odkaz:
https://doaj.org/article/869803bd076541b9a9aa02ca2da6a669
Autor:
Pía Loren, Yuliannis Lugones, Nicolás Saavedra, Kathleen Saavedra, Isis Páez, Nelia Rodriguez, Patricia Moriel, Luis A. Salazar
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1206 (2022)
Cisplatin (cis-diamminedichloroplatinum (II), DDP) is an antineoplastic agent widely used in the treatment of solid tumors because of its extensive cytotoxic activity. However, the main limiting side effect of DDP use is nephrotoxicity, a rapid deter
Externí odkaz:
https://doaj.org/article/a31020eba7b7417db045dc2af4ce4834
Autor:
Gabriel A. Rojas, Nicolás Saavedra, Kathleen Saavedra, Montserrat Hevia, Cristian Morales, Fernando Lanas, Luis A. Salazar
Publikováno v:
Toxics, Vol 10, Iss 9, p 497 (2022)
The particulate matter present in air pollution is a complex mixture of solid and liquid particles that vary in size, origin, and composition, among which are polycyclic aromatic hydrocarbons (PAHs). Although exposure to PAHs has become an important
Externí odkaz:
https://doaj.org/article/78c2748a083a4350b495a467ccc0eda1
Autor:
Jesús Herrera-Bravo, Jorge F. Beltrán, Nolberto Huard, Kathleen Saavedra, Nicolás Saavedra, Marysol Alvear, Fernando Lanas, Luis A. Salazar
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1239 (2022)
Grape pomace is a source of anthocyanins, which can prevent cardiovascular diseases due to their antioxidant properties. Anthocyanin activity is associated with the ability to regulate oxidative stress through the transcription factor Nrf2. Thus, the
Externí odkaz:
https://doaj.org/article/1b13f72b6e374e0abfce6c9f7ccefb8d
Autor:
Carmen Gloria Ubilla, Yalena Prado, Jeremy Angulo, Ignacio Obreque, Isis Paez, Nicolás Saavedra, Kathleen Saavedra, Tomás Zambrano, Luis A. Salazar
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Evidence accumulated so far indicates that circulating levels of microRNAs (miRNAs) are associated with several pathologies. Therefore, differential expression of extracellular miRNAs exhibits promising potential for screening and diagnosis purposes.
Externí odkaz:
https://doaj.org/article/c9f8c3b5acd54efcbb87e454a28a165b