Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathleen S. Hannon"'
Publikováno v:
Journal of Bone and Mineral Research. 2:449-456
To determine whether the nonsteroidal antiestrogen tamoxifen behaves as either an agonist or antagonist of estrogen on bone, the effects of ovariectomy, 17 beta-estradiol, and tamoxifen were compared on radial growth at the tibial diaphysis in young
Publikováno v:
Journal of Bone and Mineral Research. 4:557-563
The effects of castration on bone histomorphometry and mineral homeostasis were compared in male and female rats. Measurements were performed 4 weeks after sham operation or gonadectomy. Orchiectomy produced increases in serum calcium and decreases i
Publikováno v:
Calcified tissue international. 59(4)
Leukemia inhibitory factor (LIF) is a single-chain polypeptide that previously was shown in mice to produce hypercalcemia and influence skeletal growth and turnover. We performed dose-response studies to determine if LIF alters the serum calcium or h
Autor:
Virginia S. Greene, Daniel P. Desimone, Russell T. Turner, Kathleen S. Hannon, Norman H. Bell
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 8(5)
The effects of prostaglandin E2 (PGE2) given in controlled-release pellets or by daily sc injection for 21 days on mineral homeostasis and bone histomorphometry were compared in 7-week-old female rats. Sham operation and ovariectomy were performed at
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 6(4)
This report describes histomorphometric evidence for an important role of androgens in maintaining cancellous bone balance at a remodeling site in vivo. Rats were orchiectomized (ORX) at 7 weeks of age and received either androgens or vehicle 1 week
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 8(4)
The physiological role of gonadal androgens in regulating bone metabolism is not established. To determine if androgens antagonize the changes in cortical bone after gonadectomy, we treated orchiectomized (ORX) rats with testosterone (T) and 5 alpha-
Publikováno v:
The American journal of physiology. 258(4 Pt 1)
The effects of dehydroepiandrosterone (DHA) on cortical bone at the tibial diaphysis and cancellous bone at the tibial metaphysis were determined in intact and ovariectomized rats. Total plasma DHA was reduced at 10 and 16 wk after ovariectomy. Intac
Publikováno v:
Alcoholism: Clinical and Experimental Research. 12:159-162
The effect of chronic alcohol consumption on the skeleton was Investigated in rats. The treated group received ethanol administered as 38% of caloric intake in a liquid diet (Sustacal) for 10 months. The control rats were pair weighted to the ethanol
Publikováno v:
Endocrinology. 122:1146-1150
The effects of the nonsteroidal antiestrogen tamoxifen were determined on trabecular bone mass in the proximal tibial metaphysis of intact and ovariectomized rats. Rats were ovariectomized at the beginning of the study. On day 7 of the study, 5-mg sl
Publikováno v:
Calcified tissue international. 43(6)
The effects of a 3-week treatment with the nonsteroidal "antiestrogen" tamoxifen were determined on cortical and trabecular bone mass of the tibiae of growing male rats that had undergone unilateral sciatic neurotomy (USN). USN resulted in decreases