Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kathleen S. Ensbey"'
Autor:
Simone A. Minnie, Olivia G. Waltner, Kathleen S. Ensbey, Stuart D. Olver, Alika D. Collinge, David P. Sester, Christine R. Schmidt, Samuel R.W. Legg, Shuichiro Takahashi, Nicole S. Nemychenkov, Tomoko Sekiguchi, Gregory Driessens, Ping Zhang, Motoko Koyama, Andrew Spencer, Leona A. Holmberg, Scott N. Furlan, Antiopi Varelias, Geoffrey R. Hill
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Autologous stem cell transplantation (ASCT) with subsequent lenalidomide maintenance is standard consolidation therapy for multiple myeloma, and a subset of patients achieve durable progression-free survival that is suggestive of long-term immune con
Externí odkaz:
https://doaj.org/article/2c28e30dc5f340428643e7a426bb204f
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background The traditional concept that heritability occurs exclusively from the transfer of germline-restricted genetics is being challenged by the increasing accumulation of evidence confirming the existence of experience-dependent transge
Externí odkaz:
https://doaj.org/article/b3b5e4d16edf40ef888e6eefe7baed43
Autor:
Takayuki Inoue, Motoko Koyama, Katsuji Kaida, Kazuhiro Ikegame, Kathleen S. Ensbey, Luke Samson, Shuichiro Takahashi, Ping Zhang, Simone A. Minnie, Satoshi Maruyama, Shinichi Ishii, Takashi Daimon, Takahiro Fukuda, Hirohisa Nakamae, Takahide Ara, Yumiko Maruyama, Ken Ishiyama, Tatsuo Ichinohe, Yoshiko Atsuta, Bruce R. Blazar, Scott N. Furlan, Hiroyasu Ogawa, Geoffrey R. Hill
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
Patients with acute leukemia who are unable to achieve complete remission prior to allogeneic hematopoietic stem cell transplantation (SCT) have dismal outcomes, with relapse rates well in excess of 60%. Haplo-identical SCT (haplo-SCT) may allow enha
Externí odkaz:
https://doaj.org/article/97b29e5bedf04c2183e944ba8e74b318
Autor:
Carolin Offenhäuser, Fares Al-Ejeh, Simon Puttick, Kathleen S. Ensbey, Zara C. Bruce, Paul R. Jamieson, Fiona M. Smith, Brett W. Stringer, Benjamin Carrington, Adrian V. Fuchs, Craig A. Bell, Rosalind Jeffree, Stephen Rose, Kristofer J. Thurecht, Andrew W. Boyd, Bryan W. Day
Publikováno v:
Cancers, Vol 10, Iss 12, p 519 (2018)
The EphA3 receptor has recently emerged as a functional tumour-specific therapeutic target in glioblastoma (GBM). EphA3 is significantly elevated in recurrent disease, is most highly expressed on glioma stem cells (GSCs), and has a functional role in
Externí odkaz:
https://doaj.org/article/4381e17df5544784962ddeec1252f9ad
Autor:
Perry F. Bartlett, Terrance G. Johns, Thomas Robertson, David Johnson, David Kadrian, Wendy Findlay, Peter Lucas, Scott Campbell, Gert Tollesson, Craig Winter, Suzanne Allan, Po Inglis, Zara C. Bruce, Kathleen S. Ensbey, Paul R. Jamieson, Rosalind L. Jeffree, John Wilson, Brett W. Stringer, Bryan W. Day, Geoffrey W. Osborne, Andrew W. Boyd
Publikováno v:
Cancers, Vol 5, Iss 2, Pp 357-371 (2013)
Brain cancer research has been hampered by a paucity of viable clinical tissue of sufficient quality and quantity for experimental research. This has driven researchers to rely heavily on long term cultured cells which no longer represent the cancers
Externí odkaz:
https://doaj.org/article/71598f0356054400891319baceffce3d
Autor:
Simon Puttick, Brett W. Stringer, Bryan W. Day, Zara C. Bruce, Kathleen S. Ensbey, Karine Mardon, Gary J. Cowin, Kristofer J. Thurecht, Andrew K. Whittaker, Michael Fay, Andrew W. Boyd, Stephen Rose
Publikováno v:
Molecular Imaging, Vol 14 (2015)
Noninvasive imaging is a critical technology for diagnosis, classification, and subsequent treatment planning for patients with glioblastoma. It has been shown that the EphA2 receptor tyrosine kinase (RTK) is overexpressed in a number of tumors, incl
Externí odkaz:
https://doaj.org/article/9b08dea40a214b6db04d3446e2bf5b38
Autor:
Martin F. Lavin, David G. Walker, Kathleen S. Ensbey, Amanda W. Kijas, Sergei Kozlov, Angus Harding, Bryan W. Day, Tara L. Roberts, Yi Chieh Lim
PDF file, 159K, Long-term growth of neurosphere cultures following IR treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b29bd24dfe8e199dac6a1be5e1b7a7d
https://doi.org/10.1158/1535-7163.22497978.v1
https://doi.org/10.1158/1535-7163.22497978.v1
Autor:
Martin F. Lavin, David G. Walker, Kathleen S. Ensbey, Amanda W. Kijas, Sergei Kozlov, Angus Harding, Bryan W. Day, Tara L. Roberts, Yi Chieh Lim
PDF file, 340K, Rad51 foci formation to measure homologous recombination repair in glioma initiaitng cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03200bfdb8698b3a02f4d80c823bc010
https://doi.org/10.1158/1535-7163.22497975.v1
https://doi.org/10.1158/1535-7163.22497975.v1
Autor:
Martin F. Lavin, David G. Walker, Kathleen S. Ensbey, Amanda W. Kijas, Sergei Kozlov, Angus Harding, Bryan W. Day, Tara L. Roberts, Yi Chieh Lim
PDF file, 478K, Long-term proliferation and tumourigenicity in glioma initiating cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3bb6c1cda86787409d1c9f9fa551c5
https://doi.org/10.1158/1535-7163.22497987
https://doi.org/10.1158/1535-7163.22497987
Autor:
Martin F. Lavin, David G. Walker, Kathleen S. Ensbey, Amanda W. Kijas, Sergei Kozlov, Angus Harding, Bryan W. Day, Tara L. Roberts, Yi Chieh Lim
Glioblastoma multiforme (GBM) is the most common form of brain tumor with a poor prognosis and resistance to radiotherapy. Recent evidence suggests that glioma-initiating cells play a central role in radioresistance through DNA damage checkpoint acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090b79caeed53fd2bd0cf9577e3c44d3
https://doi.org/10.1158/1535-7163.c.6535761
https://doi.org/10.1158/1535-7163.c.6535761