Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathleen Raye"'
Autor:
Kathleen Raye, Daniel T. W. Chu, Jacob J. Plattner, Akiyo Claiborne, L. Seif, Qun Li, Bryan S. Macri
Publikováno v:
Tetrahedron Letters. 36:8391-8394
Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from et
Autor:
Daniel T. W. Chu, Bryan S. Macri, L. Seif, Jacob J. Plattner, Qun Li, Kathleen Raye, Akiyo Claiborne
Publikováno v:
ChemInform. 27
Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from et
Autor:
Deanne Crowell, Michael D. Tufano, Kennan C. Marsh, Kristine B. Berst, Jacob J. Plattner, Lisa A. Hasvold, Daniel T. W. Chu, Qun Li, Angela M. Nilius, Linus L. Shen, Weibo Wang, Kathleen Raye, Akiyo K. Claiborne, Jeff Alder, Robert K. Flamm
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(15)
The 8-position side chain of 2-pyridones is believed to be involved in the binding with bacterial DNA gyrase to form the ternary complex, making them very important for the activity of 2-pyridones. A series of 2-pyridones having fluoro-substituted am
Autor:
Qun Li, Daniel T. W. Chu, Akiyo Claiborne, Curt S. Cooper, Cheuk M. Lee, Kathleen Raye, Kristine B. Berst, Pamela Donner, Weibo Wang, Lisa Hasvold, Anthony Fung, Zhenkun Ma, Michael Tufano, Robert Flamm, Linus L. Shen, John Baranowski, Angela Nilius, Jeff Alder, Jonathan Meulbroek, Kennan Marsh, DeAnne Crowell, Yuhua Hui, Louis Seif, Laura M. Melcher, Rodger Henry, Steven Spanton, Ramin Faghih, Larry L. Klein, S. Ken Tanaka, Jacob J. Plattner
Publikováno v:
Journal of medicinal chemistry. 39(16)
Two novel series of 2-pyridones were synthesized by transposition of the nitrogen of 4-quinolones to the bridgehead position. This subtle interchange of the nitrogen atom with a carbon atom yielded two novel heterocyclic nuclei, pyrido[1,2-alpha]pyri
Autor:
Lisa A. Hasvold, Jacob J. Plattner, William Arnold, Thomas J. Sowin, Qun Li, Akiyo Claiborne, Laura Melcher, Daniel T. W. Chu, Weibo Wang, Anthony K. L. Fung, Hormoz Mazdiyasni, Linda Lijewski, Xiaolin Zhang, Kathleen Raye
Publikováno v:
HETEROCYCLES. 51:1345