Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kathleen Ran"'
Autor:
Jing Yang, Wei Yin, Richard Van, Keyi Yin, Peng Wang, Chao Zheng, Biyue Zhu, Kathleen Ran, Can Zhang, Mohanraja Kumar, Yihan Shao, Chongzhao Ran
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Detection of amyloid beta deposits is often performed with fluorescent compounds that bind plaques. Here the authors develop turn-on chemiluminescent probes that bind amyloid beta plaques in vivo, and amplify the signal via chemiluminescence resonanc
Externí odkaz:
https://doaj.org/article/1b0e2d17a1284d778ce3f42a0c81effe
Publikováno v:
Molecules, Vol 25, Iss 4, p 863 (2020)
CRANAD-28, a difluoroboron curcumin analogue, has been demonstrated in earlier reports to successfully label amyloid beta (Aβ) plaques for imaging both ex vivo and in vivo. CRANAD-28’s imaging brightness, ability to penetrate the blood brain barri
Externí odkaz:
https://doaj.org/article/388c388ff4a642829c7ee406cd382aeb
Autor:
Nair, Sumil K., Xie, Michael E., Anita Kalluri, Kathleen Ran, Collin Kilgore, Halbert-Elliott, Kyra, Judy Huang, Michael Lim, Bettegowda, Chetan, Risheng Xu
Publikováno v:
Journal of Neurosurgery; Apr2024, Vol. 140 Issue 4, p1155-1159, 5p
Autor:
Sumil K. Nair, Michael E. Xie, Kathleen Ran, Anita Kalluri, Collin Kilgore, Judy Huang, Michael Lim, Chetan Bettegowda, Risheng Xu
Publikováno v:
World Neurosurgery. 173:e542-e547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14271cf9b4804cf983813615b99bf307
https://doi.org/10.1016/j.wneu.2023.02.090
https://doi.org/10.1016/j.wneu.2023.02.090
Autor:
Biyue Zhu, Jing Yang, Richard Van, Fan Yang, Yue Yu, Astra Yu, Kathleen Ran, Keyi Yin, Yingxia Liang, Xunuo Shen, Wei Yin, Se Hoon Choi, Ying Lu, Changning Wang, Yihan Shao, Liang Shi, Rudolph E. Tanzi, Can Zhang, Yan Cheng, Zhirong Zhang, Chongzhao Ran
Publikováno v:
Chemical science. 13(27)
Small molecules and antibodies are normally considered separately in drug discovery, except in the case of covalent conjugates. We unexpectedly discovered several small molecules that could inhibit or enhance antibody-epitope interactions which opens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bacc3f39af61a006a9d7608bb9853f
https://pubmed.ncbi.nlm.nih.gov/35919434
https://pubmed.ncbi.nlm.nih.gov/35919434
Autor:
Pernille Bronken Eidesen, Anne Krag Brysting, Kathleen Rani Hagen, Simen Salomonsen Hjelle, Aloïs Revéret, Ingrid Vesterdal Tjessem, Martin Čertner, Jorge Gago, Mie Prik Arnberg, Johanna Behrisch, Katrín Björnsdóttir, Viktorie Brožová, Angeline J.H.M. Bruls, Kathrin Driehaus, Janna Einöder, Ragnhild Gya, Valentina Handle, Niki Meinert Hansen, Maria Huntsaar, Anne Hølmkjær Jacobsen, Kayden Kendrick, Christine Mikalsen, Eike Müller, Sondre Kaastad Sørsdal, Jóhannes Bjarki Urbancic Tómasson, Inger Kristine Volden
Publikováno v:
Arctic Science (2024)
The ecological and evolutionary consequences of ploidy-driven trait variation, particularly for autopolyploids, remain poorly understood. Saxifraga oppositifolia L. (purple saxifrage), is a highly successful arctic-alpine plant species with significa
Externí odkaz:
https://doaj.org/article/3c7923920e7b472ebbe2021f5626816b
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3653165074eee491469572b91833dd
https://doi.org/10.1002/alz.041185
https://doi.org/10.1002/alz.041185
Autor:
Chao Zheng, Wei Yin, Mohanraja Kumar, Jing Yang, Keyi Yin, Peng Wang, Can Zhang, Chongzhao Ran, Biyue Zhu, Kathleen Ran, Yihan Shao, Richard Van
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Turn-on fluorescence imaging is routinely studied; however, turn-on chemiluminescence has been rarely explored for in vivo imaging. Herein, we report the design and validation of chemiluminescence probe ADLumin-1 as a turn-on probe for amyloid beta (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e948428b650aba296d3941887d920639
https://doi.org/10.1038/s41467-020-17783-4
https://doi.org/10.1038/s41467-020-17783-4
Autor:
Chao Zheng, Jing Yang, Richard Van, Keyi Yin, Wei Yin, Biyue Zhu, Kathleen Ran, Peng Wang, Can Zhang, Yihan Shao, Chongzhao Ran
Fluorescence and chemiluminescence imaging are the most widely applied optical emissive imagingmethods in biomedical research. “Smart” (turn-on) fluorescence imaging has been routinely used for invitro, cellular, and in vivo imaging; however, sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9a47ecfc07c06d3ef65691eeba055d
https://doi.org/10.26434/chemrxiv.12142578.v1
https://doi.org/10.26434/chemrxiv.12142578.v1
Autor:
Biyue Zhu, Jing Yang, Keyi Yin, Se Hoon Choi, Zhirong Zhang, Wei Yin, Nolan Shen, Kathleen Ran, Yihan Shao, Chongzhao Ran, Rudolph E. Tanzi, Ying Lu, Changning Wang, Can Zhang, Yan Cheng, Yingxia Liang, Richard Van
The interaction between an antibody and its epitope has been daily utilized in various biological studies; however it has been rarely explored whether small molecules can alter the interaction. We discovered that small molecules could alter/edit surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2cc6ad54b34ffffde05ad1028fcb65
https://doi.org/10.1101/838896
https://doi.org/10.1101/838896