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pro vyhledávání: '"Kathleen R. Whitten"'
Autor:
Marlene L. Cohen, Kathleen R. Whitten, Jerry W. Misner, Marzoni Gifford P, William L. Garbrecht
Publikováno v:
Journal of Medicinal Chemistry. 33:652-656
A series of (8 beta)-6-methylergoline amide derivatives was synthesized with various alkyl substituents in the N1-position in order to evaluate their effectiveness in blocking vascular 5HT2 receptors. The influence of both the N1 substituent and amid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124f46d93da8a39c6b9823d48fd344c2
https://doi.org/10.1021/jm00164a029
https://doi.org/10.1021/jm00164a029
Publikováno v:
Journal of medicinal chemistry. 31(2)
A series of (8 beta)-6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid cycloalkyl esters were prepared and examined for blockade of vascular 5HT2 receptors. The antagonist in this series that had the highest 5HT2 receptor affinity was (8 beta)-6-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a6f221ef47c6716d6c62b92ee4c4c6
https://pubmed.ncbi.nlm.nih.gov/3339614
https://pubmed.ncbi.nlm.nih.gov/3339614