Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kathleen R Allinson"'
Autor:
Simon Tual-Chalot, Marwa Mahmoud, Kathleen R Allinson, Rachael E Redgrave, Zhenhua Zhai, S Paul Oh, Marcus Fruttiger, Helen M Arthur
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98646 (2014)
Rare inherited cardiovascular diseases are frequently caused by mutations in genes that are essential for the formation and/or function of the cardiovasculature. Hereditary Haemorrhagic Telangiectasia is a familial disease of this type. The majority
Externí odkaz:
https://doaj.org/article/5d52fe5818944569bdd0265c10f358a5
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39336 (2012)
TGFβ signalling in endothelial cells is important for angiogenesis in early embryonic development, but little is known about its role in early postnatal life. To address this we used a tamoxifen inducible Cre-LoxP strategy in neonatal mice to deplet
Externí odkaz:
https://doaj.org/article/c8dfbef68226485da1dd33f33d6890de
Autor:
Sophie Howarth, Georgina Sneddon, Kathleen R Allinson, Salman Razvi, Anna L Mitchell, Simon H S Pearce
Publikováno v:
European Journal of Endocrinology. 188
Autoimmune Addison's disease (AAD) arises from a complex interplay between multiple genetic susceptibility polymorphisms and environmental factors. The first genome wide association study (GWAS) with patients from Scandinavian Addison's registries ha
Publikováno v:
PLoS ONE, Vol 7, Iss 9 (2012)
Externí odkaz:
https://doaj.org/article/2a8e62aaa7ef4ab1bc32e643cbda5c59
Autor:
Lorna C Gilligan, Angela E Taylor, Catherine Napier, Earn H Gan, Wiebke Arlt, Simon H. S. Pearce, Anna L. Mitchell, Kathleen R. Allinson
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context The natural history of adrenal function in autoimmune Addison disease once diagnosed and treated has not been systematically studied, but several case reports of recovery from established adrenal failure suggest it may not be uniform. Objecti
Publikováno v:
Endocrine Abstracts.
Autor:
Ishita Bhatnagar, Salman Razvi, Katy Campbell, Laura C Lane, Simon H. S. Pearce, Tim Cheetham, Anna L. Mitchell, Heather J. Cordell, Lorna Ingoe, Kathleen R. Allinson
Publikováno v:
Clinical endocrinology. 90(1)
OBJECTIVE B lymphocyte activating factor (BAFF), a member of the tumour necrosis factor superfamily, is essential for B cell activation, differentiation and survival. Elevated circulating BAFF levels have been found in patients with several autoimmun
Publikováno v:
Endocrine Abstracts.
Autor:
Kathleen R. Allinson, Robert H. Anderson, Andrew Robson, Helen M. Arthur, Deborah J. Henderson
Publikováno v:
Developmental Dynamics. 239:2435-2442
TGFβ signalling is required for normal cardiac development. To investigate which cell types are involved, we used mice carrying a floxed Type II TGFβ receptor (Tgfbr2fl) allele and Cre-lox genetics to deplete this receptor in different regions of t
Publikováno v:
Journal of visualized experiments : JoVE. (77)
Angiogenesis is the complex process of new blood vessel formation defined by the sprouting of new blood vessels from a pre-existing vessel network. Angiogenesis plays a key role not only in normal development of organs and tissues, but also in many d