Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathleen N. Klinzing"'
Autor:
Wezley C. Griffin, David R. McKinzey, Kathleen N. Klinzing, Rithvik Baratam, Achini Eliyapura, Michael A. Trakselis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The MCM8/9 helicase has been implicated in DNA recombination processes with mutations in these genes causative for infertility and cancer. Here, the authors show that MCM8/9 aids normal fork progression and also stabilizes persistently stalled forks,
Externí odkaz:
https://doaj.org/article/b065c20a999744f3b6317e6f71efc98a
Autor:
Wezley C. Griffin, David R. McKinzey, Kathleen N. Klinzing, Rithvik Baratam, Michael A. Trakselis
The minichromosome maintenance (MCM) 8/9 helicase is a AAA+ complex involved in DNA replication-associated repair. Despite high sequence homology to the MCM2-7 helicase, an active role for MCM8/9 has remained elusive. We interrogated fork progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946417fc44df69538c31400d8c22ef89
https://doi.org/10.1101/2021.12.08.471807
https://doi.org/10.1101/2021.12.08.471807
Autor:
Wezley C. Griffin, David R. McKinzey, Kathleen N. Klinzing, Rithvik Baratam, Achini Eliyapura, Michael A. Trakselis
Publikováno v:
Nature communications. 13(1)
The minichromosome maintenance (MCM) 8/9 helicase is a AAA+ complex involved in DNA replication-associated repair. Despite high sequence homology to the MCM2-7 helicase, a precise cellular role for MCM8/9 has remained elusive. We have interrogated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a360368b7f0db3593f7487adff5c7cfd
https://pubmed.ncbi.nlm.nih.gov/36042199
https://pubmed.ncbi.nlm.nih.gov/36042199
Autor:
Michael A. Trakselis, Shivasankari Gomanthinayagam, David R. McKinzey, Elizabeth P. Jeffries, Kathleen N. Klinzing, Wezley C Griffin, Aleksandar Rajkovic
Publikováno v:
The Journal of Biological Chemistry
The MCM8/9 complex is implicated in aiding fork progression and facilitating homologous recombination (HR) in response to several DNA damage agents. MCM9 itself is an outlier within the MCM family containing a long C-terminal extension (CTE) comprisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4d8b4ba7cf75b63f88c53a1b22a8fa
https://doi.org/10.1016/j.jbc.2021.100355
https://doi.org/10.1016/j.jbc.2021.100355
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca99ad951f0305c8d02a25bcff948d2
https://doi.org/10.1096/fasebj.2020.34.s1.07234
https://doi.org/10.1096/fasebj.2020.34.s1.07234