Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathleen Mortell"'
Autor:
Janice M. Friis, Charlotte Wu, Sara E. Morin, Joaquim Trias, Bore Raju, Wade J. Adams, Ford Charles W, Ronda D. Schaadt, Stuart Lam, Joe Palandra, Dinesh V. Patel, Joseph Zhou, Maria Courtney, Mikhail F. Gordeev, Sara Lopez, Gary E. Zurenko, C J Hackbarth, Upinder Singh, Robert C. Gadwood, Zhengyu Yuan, Kathleen Mortell
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4209-4212
Combinatorial libraries of N-acylated 5-(S)-aminomethyloxazolidinone derivatives of S-oxide and S,S-dioxide tetrahydro-4(2H)-thiopyranyl and thiomorpholine phenyloxazolidinone series have been synthesized on a solid phase and evaluated for antimicrob
Autor:
Teodozyj Kolasa, Kathleen Mortell, Renje Chang, Jorge D. Brioni, Meena V. Patel, Marc A. Terranova, Brenda Martino, Masaki Nakane, Robert B. Moreland, Odile F. El Kouhen, Andrew O. Stewart, Marian T. Namovic, Pramila Bhatia, Mark A. Matulenko, Diana L. Donnelly-Roberts, Peter R. Hollingsworth, Marie E. Uchic, Loan N. Miller, Kennan C. Marsh, Gin C. Hsieh, Rodger F. Henry, Ahmed A. Hakeem, Jill M. Wetter
Publikováno v:
Journal of medicinal chemistry. 49(17)
A new series of dopamine D4 receptor agonists, 1-aryl-3-(4-pyridinepiperazin-1-yl)propanone oximes, was designed through the modification of known dopamine D4 receptor agonist PD 168077. Replacement of the amide group with a methylene-oxime moiety pr
Autor:
Dinesh V. Patel, Richard C. White, Zhengyu Yuan, Charlotte Wu, Kathleen Mortell, Marcela Gomez, Wen Wang, Joaquim Trias, Hardwin O'dowd, Bore Raju, Sampath-Kumar Anandan, Hongwu Gao, C J Hackbarth
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(14)
Negamycin 1 is a bactericidal antibiotic with activity against Gram-negative bacteria, and served as a template in an antibiotic discovery program. An orthogonally protected β-amino acid derivative 3a was synthesized and used in parallel synthesis o